Using this concise yet complete introduction to all aspects of biological membranes and their responses to toxicants, the reader will understand the role of cell membranes in controlling uptake, distribution, extrusion and excretion of toxic xenobiotics.
Help your child power up their reading skills and learn all about a teacher s day with this fun-filled non-fiction reader carefully levelled to help children progress.
This book offers a comprehensive exploration of brain tumors, beginning with a foundational understanding of their pathophysiology and extending through the latest advancements in diagnosis and treatment.
"e;Real-life"e; crime dramas on television intrigue us with the details of postmortem examinations leading to the arrest of murder suspectsbut how do forensic pathologists, the doctors who investigate unnatural deaths and chilling crime scenes, actually bring criminals to justice?
Mechanobiology-the study of the effects of mechanical environments on the biological processes of cells-has evolved from traditional biomechanics via the incorporation of strong elements of molecular and cell biology.
Detecting Signals at the Single Molecule Level: Pioneering Achievements in MicroscopyRecent advances have led to such remarkable improvements in fluorescence lifetime imaging microscopy's (FLIM) capacity for contrast and sensitivity that researchers can now employ it to detect signals at the single molecule level.
A Focused, State-of-the-Art Overview of This Evolving FieldPresents Various Techniques for GlycoinformaticsThe development and use of informatics tools and databases for glycobiology and glycomics research have increased considerably in recent years.
The basal ganglia are involved in complex brain functions, from voluntary movement control to learning and reward processing, and they are implicated in numerous neurological and psychiatric disorders.
Although the amount of research on copper amine oxidases has grown rapidly and substantially in the past decade, the field unfortunately suffers from lack of cohesion and significant confusion surrounds aspects as simple as confirmation of enzyme identities.
With chapter contributions from more than 30 metal biology experts, Cellular and Molecular Biology of Metals explains the role of key divalent metal ions involved in the molecular and cellular biology of various target cell populations.
Presents the Therapeutic Potential for Caspase Inhibitors: Present and FutureCaspases represent one of the most specific protease families described to date.
The recognition of oxidative stress as a major factor in health, aging, and disease has led to a surge in research aimed at uncovering effective countermeasures in the form of antioxidants.
Characterized by obesity, insulin resistance, dyslipidemia, and hypertension, metabolic syndrome is associated with the risks of type 2 diabetes mellitus and cardiovascular disease.
In situ hybridization is a technique that allows for the visualization of specific DNA and RNA sequences in individual cells, and is an especially important method for studying nucleic acids in heterogeneous cell populations.
The dangers and drawbacks inherent in radioactivity-based methods along with a demonstrated and dramatic increase in sensitivity have precipitated a major shift towards luminescence measurements and visualization techniques.
Immunologists as well investigators in other disciplines may often use protocols involving the isolation, cultures and characterization of different types of leukocytes.
Poly (ADP-ribose) polymerase (PARP), also termed poly (ADP-ribose) synthetase (PARS) is a nuclear enzyme with a wide range of functions, including regulation of DNA repair, cell differentiation, and gene expression.
As the first detailed overview of the subject, Tight Junctions brought together diverse perspectives from leading investigators to provide a multidisciplinary overview of the field.
Prion-related diseases, known as transmissible spongiform encephalopathies (TSEs), are infectious, fatal neurodegenerative disorders for which there is no cure, treatment, nor even a means for early diagnosis.
A step-by-step guide to commonly used procedures, Methods in Cellular Immunology addresses both human and murine models, in addition to such topics as PCR and apoptosis.
The Japanese Ministry of Health, Labor and Welfare, officially recognizing that various risk factors for disease are present in our environment, has proposed the concept of lifestyle-related diseases.
While adenosine triphosphate (ATP) is described as the universal currency of energy in all living organisms at the cellular level, the actual power lies in its phosphate tail.
New Findings Revolutionize Concepts of Gene FunctionEndogenous small RNAs have been found in various organisms, including humans, mice, flies, worms, fungi, and bacteria.
The ability of molecular and cellular imaging to track the survival, migration, and differentiation of cells in vivo as well as monitor particular gene expression in living subjects is rapidly moving from the research laboratory into daily clinical settings.
Soft condensed matter physics, which emerged as a distinct branch of physics in the 1990s, studies complex fluids: liquids in which structures with length scale between the molecular and the macroscopic exist.
Since the first Handbook of Cell-Penetrating Peptides was prepared in 2001, the wealth of new information on the use of these peptides as transport systems has in fact served to confound the field.
ATP's powerful impact on the heart and blood vessels was first described in 1929, but it was not until the 1970s that ATP was proposed as the 'purinergic' neurotransmitter in autonomic nerves.
Since the discovery of Glutathione S-Transferase (GST) or Glutathione transferase, studies have probed important questions about its pharmacological and physiological significance.
Top Investigators Explore the Complexities of Angiogenesis Cancer ResearchThe targeting of tumor angiogenesis has evolved into one of the most widely pursued therapeutic strategies.
