This book is about the recent advances in the structural and functional characterization of receptors that influence intracellular signalling events through interaction with intracellular GTP-binding proteins (G proteins).
In 1994, when the International Cell Death Society was founded, programmed cell death and apoptosis had just recently been recognized as major factors in medicine, important in diseases such as cancer, neurodegenerative diseases, autoimmune diseases, and developmental anomalies.
The book entitled "e;Lactate Dehydrogenase (LDH): Biochemistry, Functions and Clinical Significance"e; provides a broad and authoritative review of the lactate dehydrogenase enzyme, including its isoforms, catalytic functions, distribution in various tissues, involvement in cancer cell metabolism and tumorigenesis, involvement in the plasmodium enzyme, various small molecule inhibitors of hLDHA and pfLDH, and clinical significance.
Droplets of Life: Membrane-Less Organelles, Biomolecular Condensates, and Biological Liquid-Liquid Phase Separation provides foundational information on the biophysics, biogenesis, structure, functions, and roles of membrane-less organelles.
Drosophila Cells in Culture, Second Edition, includes comprehensive coverage of cell lines, methods for creating cell lines, methods for genome engineering, and the use of cell lines for genome wide rNAi screens.
Celiac Disease, Volume 179 in the Methods in Cell Biology series is composed of extensive protocols about novel and widely used techniques for celiac disease research.
This book comprises a collection of chapters describing topics from traditional radiation cytogenetic analysis methods to the modern fluorescence based-analysis and high throughput automatic analysis methods.
This updated monograph deals with methanogenic endosymbionts of anaerobic protists, in particular ciliates and termite flagellates, and with methanogens in the gastrointestinal tracts of vertebrates and arthropods.
The cytoskeleton is comprised of a variety of specialized proteins, and is a dynamic structure that is involved in the majority of key cellular events.
From the discovery of Pdx1, the first "e;master gene"e; of pancreatic development, to the most recent findings on the role of microRNAs in beta cell homeostasis, the last fifteen years have seen an unprecedented advance in our understanding of the precise development and organization of the many different cell types that make up the pancreas.
Advances in Applied Microbiology, Volume 127 continues the comprehensive reach of this widely read and authoritative review source in microbiology where users will find invaluable references and information on a variety of areas relating to the topics of microbiology.
The rapid developments in immunology in recent immunomodulatory drugs can be distinguished years have dramatically expanded our knowledge of from their beneficial therapeutic effects.
This publication is unique among a number of books on cyanobacteria because it focuses on the bioenergetics of these widespread organisms which are the evolutionary prerequisite for the development of all higher forms of life on our "e;blue"e; planet.
SPIDERS AND OTHER ARTHROPODS: Elementary- to middle-school readers will explore amazing facts about arthropods in this 32-page nonfiction science book, which takes children on a journey with some of the most exciting (and dangerous?
Molecular Biology: Structure and Dynamics of Genomes and Proteomes second edition illustrates the essential principles behind the transmission and expression of genetic information at the level of DNA, RNA, and proteins.
A major update of a best-selling textbook that introduces students to the key experimental and analytical techniques underpinning life science research.
This unique resource-the first book of its kind exclusively devoted to the subject-offers timely coverage of the cells, mechanisms, and proteins involved in allergic inflammation, emphasizing the latest advances in local cell recruitment.
This volume expands on the previous edition with a more extensive look at molecular motors and their roles in muscle contractions, vesicle transport, flagellar beating, chromosome segregation, and DNA replication and repair.
In view of rapidly growing research in the deregulation of proteases and their impact in human health and diseases, this book will highlight existing and emerging research in this exciting area.
This book details advances in research regarding cilia, mucus, and mucociliary clearance, examining changes in mucus expression and goblet cell metaplasia, and assessing the ability of the mucociliary system to respond to abnormalities.
This detailed volume explores experimental strategies and protocols for the expression, assembly, characterization, and exploitation of transmembrane -barrel proteins.
The role of the cytokine macrophage migration inhibitory factor (MIF) in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well-established.
This detailed book explores the interactions between different types of cells and immune cells, focusing on how their functionality is affected by immunosenescence.
Sertoli Cell Biology, Second Edition summarizes the progress since the last edition and emphasizes the new information available on Sertoli/germ cell interactions.