Hedgehog-GLI Signaling in Human Disease represents the first compilation of up-to-date reviews by top-level scientists in this important field of research.
Fertilization provides in-depth reviews of individual research topics, while emphasizing key concepts and the significance of findings within other fields.
Redox Signaling in Wound Healing in Elderly Populations: Theoretical Basis, Part 1 deals with wounds in different types and locations (diabetic, ischemic, post-operational) in subcellular and macro dimensions, examine their relationship with aging aim to target deteriorating redox signaling cascades, and will also focus on promising therapeutic approaches.
In Moving Beyond Self-Interest, psychologists, neuroscientists, economists, and political scientists discuss and extend cutting-edge developments in the science of caring for and helping others.
Methods in Cell Biology Volume 155 provides an update on the step-by-step "e;how-to"e; methods to study mitochondrial structure, function and biogenesis contained in the first two editions.
Our understanding of the genetic and developmental mechanisms underlying scoliosis is rapidly evolving, this timely second edition of The Genetics and Development of Scoliosis is to provide researchers, clinicians, and students with the most current views in this field.
Adoptive Cell Transfer, Volume 370 in the International Review of Cell and Molecular Biology series highlights advances in the field, with this new volume presenting interesting chapters written by an international board of authors who expound on topics such as the Impact of tumor microenvironment on Adoptive Cell Transfer activity, Dendritic Cell Transfer, CAR-T Cell dysfunction and exhaustion, NK Cell-based cancer immunotherapy, Enabling CAR-T cells for solid tumors: rage against the suppressive tumor microenvironment, Improving Adoptive T-Cell therapy with cytokines administration, and What will (and should) be improved in Immunotherapy with CAR?
A subgroup of homeobox genes, which play an important role in the developmental processes of a variety of multicellular organisms, Hox genes have been shown to play a critical role in vertebrate pattern formation.
Advances in Stem Cells and Their Niches addresses stem cells during development, homeostasis, and disease/injury of the respective organs, presenting new developments in the field, including new data on disease and clinical applications.
This book introduces readers to the biology of leukemia stem cells (LSCs) and emphasizes the necessity and importance of targeting LSCs in the treatment of hematopoietic malignancies.
This book provides an overview on the organization andfunction of the microtubule cytoskeleton, which is essential to many cellularprocesses and profoundly linked to a range of human diseases.
This addition to the Springer Brief in Stem Cells series focuses on aspects related to the specific mechanisms that ensure and control pluripotency and cell commitment in domestic animal species.
Planarians, a class of flatworm, are extraordinary: they possess the remarkable ability to regenerate lost body parts, including complete regeneration of the nervous system.
This book provides a comprehensive update on the latest information and knowledge which emerged from translational and basic science research endeavors, targeting the regeneration of salivary glands.
In this volume, the contributing authors from top labs involved in stem cell theranostics share the latest advances in the field of stem cell research.
Research in recent years has increasingly shifted away from purely academic research, and into applied aspects of the discipline, including climate change research, conservation, and sustainable development.
This volume contains the proceedings of the NATO ARW on 'Biological Pattern Formation' held at Merton College, University of Oxford, on 27-31 August, 1992.
"Parecía merecer la pena probar hasta qué punto el principio de la evolución vertía luz en algunos de los problemas más complejos de la historia natural del hombre.
MCB: CAR T Cells: Development, Characterization and Applications, Volume 167 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including High-efficiency of genetic modification using CRISPR/Cpf1 system for engineered CAR T-cell therapy, Determination of the Biodistribution of Chimeric Antigen Receptor-Modified T Cells against CD19 in NSG Mice, Generation of CAR-T cells using lentiviral vectors, Generation of CAR T-cells using y-retroviral vector, Flow cytometry detection and quantification of CAR T cells into solid tumors, Evaluation of CAR-T Cell Cytotoxicity: Real-Time Impedance-Based Analysis, and much more.
Introduces Groundbreaking Approaches for Assessing Lectin Function Lectins and their ligands are under quite a heavy microscope due to their potential applications to pharmacology, immunology, cancer therapy, and agriculture.
Neural Crest and Placodes provides in-depth coverage of the topic, including information on their critical role in vertebrate development, evolution, and the way defects in their development underlie a wide range of congenital disorders.
The science of change from cells to cultureCells to Civilizations is the first unified account of how life transforms itself-from the production of bacteria to the emergence of complex civilizations.
Most textbooks and atlases of human anatomy chronicle only a few cases of muscle variations in the "e;normal"e; human population, or of muscle anomalies within congenital malformations.
This detailed new edition aims to provide a range of methods and protocols for studying vascular morphogenesis in vivo and in vitro to reflect up-to-date advances in the field.
This contributed volume covers all fundamental principles for researchers and professionals interested in the field of Biomaterials and Tissue Engineering, an interdisciplinary field of research with contributions from biomedical scientists, engineers, and physicians.
This textbook presents essential and accessible information about human embryology including practical information on human health issues and recent advances in human reproductive technology.
Blast is an important foliar disease that infects the majority of cereal crops like rice, finger millet, pearl millet, foxtail millet and wheat, and thus resulting in a huge economic impact.
Circadian Rhythms in Health and Disease, Volume 393 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.