Although embryonic stem cells currently enjoy the public limelight and show great pr- ise for cell based medical therapies, it is the adult stem cells which are responsible for the body's natural ability to fght disease, heal and recover, or fail and succumb to various maladies.
Interest in a specialized microenvironment or "e;niche"e; regulating hemopoietic stem cell function has been steadily growing since the idea was first proposed by Ray Schofield over three decades ago.
In Epiblast Stem Cells: Methods and Protocols, expect researchers in the field provide a detailed collection of techniques and protocols useful to the study of the biology of the pluripotent epiblast.
During the last decade, an increased interest in somatic stem cells has led to a flurry of research on one of the most accessible tissues of the body: skin.
This volume looks at the latest technologies and methods--combined with new genetic tools available in animal models--used in this constantly evolving field.
Micropropagation is a reliable technology applied commercially worldwide for large-scale plant multiplication, germplasm conservation, pathogen elimination, genetic manipulations and supply of selected plants.
This is an introductory textbook for the study of human evolution, and covers all major topics of human origins taught under paleoanthropology, anthropology, archaeology, and evolutionary biology courses.
The book provides a comprehensive overview of classic and modern approaches of centrosome research, including new aspects of centrosome functions focusing on primary cilia and their implications in numerous diseases.
This volume presents the latest techniques used to study germ cell tumors (GCTs), including histopathology; in vitro and in vivo techniques for investigating GCT biology; novel methods for detecting minimal residual diseases; and sequencing considerations as they apply to GCTs.
Charles Darwin desempeñó un papel crucial a la hora de convertir la herencia en una cuestión científica y, sin embargo, fracasó estrepitosamente a la hora de responderla.
This book covers a broad range of therapeutic applications of nanomaterials that are used for regenerative medicine applications, including neural regeneration, cartilage regeneration, wound healing, dental regeneration and implants, and immunomodulation.
This book presents state-of-the-art pre-clinical models and clinical applications of stem-cell-based therapies applied to different lung diseases, with a special focus on the translation of bench data into clinical studies.
This volume covers the current knowledge base on the role of signaling and environmental pathways that control the normal development of germline stem cells, meiotic progression of oocytes, events of oocyte maturation and fertilization, and the birth of an embryo.
This book provides a comprehensive overview of topics describing the earliest steps of fertilization, from egg activation and fertilization to the activation of the zygotic genome, in various studied vertebrate model systems.
This book is the first comprehensive volume on the genetics and genomics of pineapple and provides an overview of the current state of pineapple research.
This book discusses the latest developments in plant-mediated fabrication of metal and metal-oxide nanoparticles, and their characterization by using a variety of modern techniques.
This book focuses on the plant cytoskeleton and its various cross-talks with other cellular components leading to its role in plant growth and development.
This book is aimed to summarise the key aspects of the role of circulating tumour cells (CTCs) in breast cancer, with special attention to their contribution to tumour progression and establishment of metastatic disease.
Mushrooms are fleshy fungi with a high prospective for the production of secondary metabolites including extracellular enzymes with high agricultural and biotechnological significance.
This book reveals the benefits of describing and modeling trees as the combined surface areas of their stems, and provides a concise overview of the fundamental grounds for adopting such an approach.
Plant growth and development is closely dependent on the plant environment, including the wide-spread presence of organic and inorganic xenobiotics and pollutants.