Neurosciences

In the last decade, neuropsychology has grown from a small subspecialty to a major component in the practice of clinical and medical psychology.

The purpose of this series is to provide an overview of recent research de- velopments in the field of alcoholism so that interested professionals and researchers may keep abreast of this complex, multidisciplinary work.

Over the last several decades, the remarkable success of science and medical technology has allowed many children with chronic illness and handicapping conditions to live longer and healthier lives.

In this book we present a conceptually integrated approach to disorders of mood.

"e;Continuities and Discontinuities in Development"e; was the theme for the Second Biennial DPRG Retreat, a three-day meeting held at Estes Park, Colorado, in June 1982.

This volume is the eighth in the Research Advances Series and the fifth published by Plenum Press.

A central problem in neurobiology concerns mechanisms that generate the pro- found diversity and specificity of the nervous system.

The mammalian central nervous system is a remarkable structure which has attracted many new investigators, as evidenced by the dramatic increase in scientific publications dealing with neurobiology.

If the reader will excuse a brief anecdote from my own intellectual history, I would like to use it as an introduction to this book.

The abuse of alcohol presents a major health problem throughout the world.

Basic Issues in Rehabilitation of the Brain Damaged Definitions Because of the vagueness surrounding the term brain damage, it is nec- essary at the outset to define the population to which this book may have some application.

This volume represents the Proceedings of the Second Inter- national Symposium on Skin Senses held on the campus of Florida State University, Tallahassee, Florida.

It is only relatively recently that neurochemists and neurobiologists have shown appreciable interest in the class of macromolecules now generally re- ferred to as complex carbohydrates, although gangliosides were, of course, first identified and studied in brain.

As a follow up to Volume 7, contributors continue to explore the latest developments in developmental psychology.

A fundamental problem in neuroscience is the elucidation of the cellular and molecular mechanisms underlying the development and function of the nervous system.

InJuly 1982 the first Dartmouth workshop on the corpus callosum took place.

The first two "e;Brain Heart Conferences"e; in Jerusalem in 1978 and 1983 were based upon the common interests of clinically orientated neurologists and cardiologists in the problems of centr'al autonomic control and autonomic disturbances of the cardiovascular system.

There was once an old Chinese man working on a hill with a boy.

This symposium entitled Calcium, Neuronal Function and Transmitter Re- lease, was in the framework of the regional meeting of the International Union of Physiological Sciences, that took place in Jerusalem between August 26-31, 1984.

This is the second volume to be based on a series of symposia being held periodically on the neurobiology of conditioning.

Proceedings of a conference of experts on cocaine addiction, this early volume documents the devastating effects of crack, then a new cocaine preparation, and its extraordinary addicting properties.

In the summer of 1984, both of us were working with Professor Yechiel Becker in the Laboratory for Molecular Virology at the Hebrew University-Hadassah Medical center in Jerusalem.

The advances in neuroimaging are occurring at a we wish to accomplish by bringing out a series of dizzying pace.

This third volume of the Advances in Clinical Neuropsy- chology series returns to the style of the first volume in that it contains contributions representing a diversity of areas.

One landmark in the long history of biological studies on the "e;slime mold"e; Physarum polycephalum was the introduction of chemi- cally defined growth conditions for the plasmodial phase of this organism in the laboratory of Harold P.

Volume 5 of Cerebral Cortex completes the sequence of three volumes on the individual functional areas of the cerebral cortex by covering the somatosensory and motor areas.

It is less than 80 years since John Newport Langley first proposed the role of "e;receptive substances"e; as the site of drug action from his obser- vations on the effects of nicotine and curare at the myoneural junction.

The last decade has generated a multitude of studies using in vitro model systems to explore growth and differentiation of the nervous system.

Nicotine is the major factor in the continuation of the smoking habit among humans.

In spite of progress in biomedical research, we know little about the causes, prevention, and treatment of the numerous mental and neurological disorders that afflict up to 15% of all individuals.

The variety of viewpoints expressed in this book illustrate the many contro- versies surrounding MDMA [1].

Experimentalists tend to revel in the complexity and multidimensionality of biological processes.

This book is based on contributions presented at the symposion "e;The Primary Afferent Neuron: A survey oj recent morpho:functional aspects.

The idea for this book developed during the course of several discussions among the editors while we were working together as staff scientists in the laboratories of the Clinical Neuro- science Branch of the National Institute of Mental Health.

This book is devoted to the description of agenesis of the corpus callosum, a congenital malformation of midline structures in the brain that may be regarded as a natural model of the "e;split-brain.

'Emphasis on new issues and emerging concepts insures that the information presented is still timely.

The sense of smell and the olfactory system have been a subject of intrinsic interest for millenia.

The idea for the present volume grew from discussions that the four of us had among ourselves and with our colleagues at recent scientific meetings.

"e;Psychopharmacology of the Aging Nervous System"e; was selected as the topic for Volume 20 of the Handbook of PsychopharmacoloffY.

The most striking fact revealed by investigations of insect neurohormones is that insects are as well supplied with neurohormones as mammals, since neurohor- mones regulate not only the functioning of the endocrine glands, prothoracic gland, and corpora allata, but also most physiological processes.

Neuropsychology has presented a particularly formidable array of devel- opments during recent years.

In June 1987, neurobiologists, immunologists, molecular biologists, virologists and neurologists from several countries met in Vancouver to discuss recent advances of relevance to multiple sclerosis.

This volume contains the proceedings of a conference held at the National Institutes of Health in Bethesda on March 21-23.

Soon after neurosurgery had advanced past the stage of that older neurosurgeons will consider their cra- removing lesions on the surface of the brain, it became niotomies quite adequate for the relief of many neu- apparent that subcortical diseased tissue could not be rological disorders that Professor Kandel shows so excised safely by the usual surgical techniques because clearly to be amenable to stereotactic intervention, of the risk of damaging overlying normal structures.