The goal of the characterization and discovery of G protein-coupled receptors, arguably the most important class of signaling molecules in humans and other vertebrates, has spawned numerous vital methodologies.
Over the past twenty years, the development of chromatin immunoprecipitation, or ChIP, assays has immensely enhanced the biological significance of the multifaceted DNA-binding proteins.
Lymphomas are lymphoid malignancies derived from B or T lymphocytes, and their study has been and still is paradigmatic for many aspects of cancer research.
The post-genomic revolution is witnessing the generation of petabytes of data annually, with deep implications ranging across evolutionary theory, developmental biology, agriculture, and disease processes.
Affecting over a hundred million individuals worldwide, retinal diseases are among the leading causes of irreversible visual impairment and blindness, and appropriate study models, especially animal models, are essential to furthering our understanding of the etiology, pathology, and progression of these endemic diseases.
From basic performing of sequence alignment through a proficiency at understanding how most industry-standard alignment algorithms achieve their results, Multiple Sequence Alignment Methods describes numerous algorithms and their nuances in chapters written by the experts who developed these algorithms.
As a model organism, zebrafish (Danio rerio) offer an opportunity to perform steadfast scientific investigations in a robust and high-throughput manner.
Central to the synthesis of proteins, the performance of catalysis, and many other physiological processes, the aberrant expression of which can be linked to human diseases including cancers, RNA has proven to be key target for therapeutics as well as a tool for therapy.
Nervous system development evolves from the well-orchestrated processes of neural induction, cell proliferation, differentiation, cell migration, survival, and synapse formation.
From the beginning of the OMICs biology era, science has been pursuing the reduction of the complex "e;genome-wide"e; assays in order to understand the essential biology that lies beneath it.
After the generation of genome sequence data from a wide variety of plants, databases are filled with sequence information of genes with no known biological function, and while bioinformatics tools can help analyze genome sequences and predict gene structures, experimental approaches to discover gene functions need to be widely implemented.
The application of optical methods for investigating neocortical circuit dynamics has greatly expanded in recent years, providing novel insights into the fascinating world of brain function.
The new genetic revolution is fuelled by Deep Sequencing (or Next Generation Sequencing) apparatuses which, in essence, read billions of nucleotides per reaction.
Gene therapy offers many conceptual advantages to treat muscle diseases, especially various forms of muscular dystrophies; however, it faces a number of unique challenges, including the need to deliver a therapeutic vector to all muscles throughout the body.
Progress in functional proteomics has been limited for a long time, partially caused by limitations in assay sensitivity and sample capacity; however, protein microarrays have the ability to overcome these limitations so that a highly parallel analysis of hundreds of proteins in thousands of samples is attainable.
Relying upon extensive global and multidisciplinary research, this book analyzes the perils of market-driven scenarios and peeps into the possibilities responsible for the failure of traditional approaches.
The book represents a multidisciplinary approach to understanding soil-landscape-vegetation relationships and, specifically, the ecophysiology of plant communities developing on sandy soils of very low fertility that are subject to seasonal flooding.
This book summarizes the recent research development concerning olive oil wastewater management: characterization, environmental impact, recovery and treatment.
Cognitive mathematics provides insights into how mathematics works inside the brain and how it is interconnected with other faculties through so-called blending and other associative processes.
This volume provides comprehensive overviews of each terrestrial cetartiodactyl species' biology including palaeontology, physiology, genetics, reproduction and development, ecology, habitat and diet.
This laboratory manual, published in cooperation with the International Society for Transgenic Technology (ISTT), provides almost all current methods that can be applied to the creation and analysis of genetically modified animals.
Channels and transporters are multi-functional proteins that mediate substrate transport and signal transmission and simultaneously act as regulators for other proteins and biosensors for environmental materials.
This book approaches biofuels from a new biotechnological perspective with the aim of equipping researchers with a thorough, up-to-date understanding of biofuel research and related technologies.
Very Short Introductions: Brilliant, Sharp, Inspiring In this exploration of the concept of the gene, Jonathan Slack looks at the discovery, nature, and role of genes in both evolution and development.
Unleashing the Potentials of Blockchain Technology for Healthcare Industries discusses blockchain and its adaptation in healthcare industries to provide a secured framework to safeguard healthcare data, both patient and hospital data.
A deeply personal master class on how to read a natural landscape and unravel the clues to its unique ecological history Structured as a series of interactive field walks through ten New England ecosystems, this book challenges readers to see the world through the eyes of a trained naturalist.
Developing Sustainable and Health Promoting Cereals and Pseudocereals: Conventional and Molecular Breeding reviews the most recent developments in the fields of cereal and pseudocereal breeding, with particular emphasis on the latest biotechnological techniques likely to lead to breakthrough changes in plant breeding.
If you think baby brain is bad for you, think again - because neuroscientist Dr Sarah McKay (author of The Women's Brain Book) has looked at studies and talked to experts from all over the world and the proof is in: giving birth is one of the best things to ever happen to a woman's brain.
The essential insider's guide for ecologists at all career stages-now completely updated and expandedMost books and courses in ecology focus on facts and concepts but do little to explain the process of research.
Viruses do not behave as other microbes; their life cycles require infecting healthy cells, commandeering their cellular apparatus, replicating and then killing the host cell.
