Cytotoxic T lymphocytes (CTL) control several viral infections in animals based on deletion and reconstitution experiments with CTL clones and use of CD8 genetically deficient (knock-out) mice.
It has been almost 20 years since the discovery by Kohler and Milstein of the technology to produce monoclonal antibodies (MAbs), a discovery that promised revolutionary changes in research, clinical diagnosis and human therapy.
With one new volume each year, this series keeps scientistsand advanced students informed of the latest developmentsand results in all areas of botany.
Understanding neutralization is particularly relevant to an appreciation of the interaction between a virus and its antibody-synthesizing host since it is likely that viruses and the antibody system have evolved in response to reciprocally imposed selective pressures.
Although upstaged by the tragic appearance of the human immunodeficiency virus, herpes simplex viruses (HSV) types 1 and 2 continue to be major human pathogens against which we lack acceptable vaccines or other means of immunological control.
In the past 5 years there has been an enormous increase of evidence that the ion channels activated by mechanical force are common to a wide variety of cell types.
Pioneering work on hepatitis B virus and hepatitis delta virus, and the discovery of hepatitis B-like virus in animals during the 1970's has been followed, over the past ten years, by an explosion of interest in how these viruses replicate, maintain chronic infections, and cause liver disease and hepatocellular carcinoma.
The present volume contains 17 lectures of the 41 st Mosbach Colloquium of the Gesellschaft fiir Biologische Chemie, held from April 5-7, 1990 on the topic "e;The Molecular Basis of Bacterial Metabolism"e;.
An integrated retrovirus effectively becomes part of the cellular genome, but with the difference that the virus to a large extent retains control over its own expression through nontranslated sequences in the long terminal repeat (L TR).
The eighth workshop in this series on Mechanisms in B-Cell Neoplasia 1990 was held in Wilson Hall at the National Institutes of Health, Bethesda, Maryland on March 28-30.
Inorganic Nitrogen in Plants and Microorganisms summarizes new experimental data, ideas and conclusions on the whole metabolic spectrum: - transport through the cell membranes, - the distribution within plant organs, - nitrate and nitrite reduction with their complicated genetic and physiological regulation, - the assimilation of ammonium and dinitrogen.
Genital Papillomavirus Infections provides a state of the art survey on the clinical aspects, diagnosis, treatment, and prevention of genital papillomavirus infections, written by experts in the respective fields.
The purpose of this volume is to highlight some current areas of poxvirus research which are likely to be particularly fruitful in the upcoming few years.
All relevant ecological aspects of plankton, especially seasonal changes in the species composition, the role of competition for limiting resources in species replacements, the role of parasitism, predation and competition in seasonal succession are treated in detail considering phytoplankton, zooplankton and bacteroplankton.
A massive phytoplankton bloom, locally termed "e;brown tide"e;, suddenly appeared in Long Island marine bays in 1985, colored the water a dark brown, decimated eelgrass beds and caused catastrophic starvation and recruitment failure of commercially important bay scallop populations.
Candida, which was discovered more than a century ago as a causative organism of oral thrush, is now thought to potentially infect almost every tissue of the human body.
A synthesis of current knowledge on retrovirology, cov- ering the literature and the relevance of this rapidly advancing area to HIV and AIDS research.
Individual cell and particle analysis in aquatic sciences isinvolved in many aspects of oceanography and limnology,including optical physics of particles, phytoplanktonphysiology and ecology, marine and aquatic microbiology andfood web interactions.
Algal systematists, geologists and evolutionary biologists provide a synthesis of the evolutionary biogeography of red, brown, and green algae of the North Atlantic Ocean also considering their relationships with species and genera in the Arctic and Pacific Oceans as well as other subtropical and tropical seas.
Named for the enlarged, inclusion-bearing cells characteristic of infection by these viruses, cytomegaloviruses present a significant challenge to both microbiologist and immunologist.
It is surprising, and even disappointing, that there have been very few meetings and published volumes resulting from these meetings that focus attention upon all of the groups of DNA tumor viruses.
Despite the many advances made during the last decade in various aspects of fungal biochemistry, there have been very few volumes devoted to the sub- ject in recent years.
Many bacteria, such as certain Neisseria and Haemophilus or Escherichia coli, are able to withstand the bactericidal activity of complement and phagocytes.
