Analytical chemistry

Surface plasmon resonance (SPR) plays a dominant role in real-time interaction sensing of biomolecular binding events and with the biosensor field expanding more applications are being found.

As a practical reference guide for designing and performing experiments, this book focuses on the five most common classes of contrast agents for MRI namely gadolinium complexes, chemical exchange saturation transfer agents, iron oxide nanoparticles, manganese complexes and fluorine contrast agents.

Biophysical techniques are used in many key stages of the drug discovery process including in screening for new receptor ligands, in characterising drug mechanisms, and in validating data from biochemical and cellular assays.

Electrochemistry is the study of chemical reactions with an exchange of electrons, and of the chemical phenomena that are caused by the action of applied currents and voltages.

Developments in optical spectroscopy have taken new directions in recent decades, with the focus shifting from understanding small gas phase molecules towards applications in materials and biological systems.

Analytical Applications of Ionic Liquids reviews the current research in analytic chemistry, covering subjects as diverse as separation science, chromatography, spectroscopy and analytical electrochemistry.

'The book is a useful contribution in the field of HPLC, and may represent a valuable tool for chromatography practitioners in different fields, as well as teachers and instructors.

Surface enhanced Raman scattering (SERS) might be one of the most impressive effects to demonstrate the power of plasmonic approaches in spectroscopy and became one of the 'triggers' for the rapidly emerging field of plasmonics.

There is a growing need for high-throughput separations in food and environmental research that are able to cope with the analysis of a large number of compounds in very complex matrices.

High-pressure materials research has been revolutionized in the past few years due to technological breakthroughs in the diamond anvil cell (DAC), shock wave compression and molecular dynamic simulation (MD) methods.

Calixarenes in Action is unique among books devoted to this interesting class of synthetic macrocycles.

Environmental analysis techniques have advanced due to the use of nanotechnologies in improving the detection sensitivity and miniaturization of the devices in analytical procedures.

Providing the first comprehensive book on the current state of hyperpolarized Xenon-129 NMR and MRI, this book is guaranteed to appeal to a wide range of scientists interested in this growing field.

Providing a definitive reference source on novel methods in NMR acquisition and processing, this book will highlight similarities and differences between emerging approaches and focus on identifying which methods are best suited for different applications.

There has been a recent surge in hardware developments with respect to mobile NMR and MRI systems, from which novel applications are starting to emerge.

Ambient ionization has emerged as one of the hottest and fastest growing topics in mass spectrometry enabling sample analysis with minimal sample preparation.

In the rapidly growing field of metabolomics, a comprehensive book describing the state of the art in the application of NMR spectroscopy will be a key title for practitioners.

The complexity and heterogeneity of biological systems has posed an immense challenge in recent years.

As a component of post-genome science, the field of proteomics has assumed great prominence in recent years.

The field of proteomics has developed rapidly over the past decade nurturing the need for a detailed introduction to the various informatics topics that underpin the main liquid chromatography tandem mass spectrometry (LC-MS/MS) protocols used for protein identification and quantitation.

Since its commercial introduction in 2004, UHPLC (Ultra-High Performance Liquid Chromatography) has begun to replace conventional HPLC in academia and industry and interest in this technique continues to grow.

The use of Compound-specific Stable Isotope Analysis (CSIA) is increasing in many areas of science and technology for source allocation, authentication, and characterization of transformation reactions.

Environmental forensics is emerging and evolving into a recognized scientific discipline with numerous applications, especially regarding chlorinated solvents.

The emerging field of lipidomics has been made possible because of advances in mass spectrometry, and in particular tandem mass spectrometry of lipid ions generated by electrospray ionization.

Over the last 150 years, the Public Analyst profession has hidden its light under a bushel, with the notable exception of Fredrick Accum, one of the first Public Analysts who published the names and addresses of food adulterers, this group of chemists has quietly protected the public from food fraud and adulteration.

Computer-Assisted Structure Elucidation (CASE) systems are a combination of software algorithms and tools to support and enable chemists and spectroscopists engaged in the process of molecular structure elucidation via the analysis of spectroscopic data.

During the last two decades, the use of NMR spectroscopy for the characterization and analysis of food materials has flourished, and this trend continues to increase today.

The different physical properties displayed by low molar mass organic materials and polymers are a result of their molecular organisation.

New techniques, improved understanding and changes in regulations relating to environmental analysis means that students, technicians and lecturers alike need an up-to-date guide to practical environmental analysis.

The first edition of this book was a first book for atomic spectroscopists to present the basic principles of experimental designs, optimization and multivariate regression.

This publication is based on peer-reviewed manuscripts from the 2014 International Network of Environmental Forensics (INEF) Conference held at St John's College, Cambridge.

The pace of revolution in analytical chemistry in the field of Geosciences has been dramatic over recent decades and includes fundamental developments that have become common place in many related and unrelated disciplines.

The ultra-bright femtosecond X-ray pulses provided by X-ray free electron lasers (XFELs) open up opportunities to study the structure and dynamics of a wide variety of systems beyond what is possible with synchrotron sources.

Guiding chromatographers working in regulated industries and helping them to validate their chromatography data systems to meet data integrity, business and regulatory needs.

This publication includes peer-reviewed manuscripts from the 2013 International Network of Environmental Forensics (INEF) Conference held at Pennsylvania State College, USA.

Spin relaxation parameters, although difficult to interpret, are attracting interest in NMR as these parameters are capable of yielding both structural and dynamic information.

There has been significant expansion and development in clinical laboratory sciences and, in particular, metrological concepts, definitions and terms since the previous edition of this book was published in 1995.

Peroxynitrite is a powerful oxidiser which can damage a wide array of molecules within cells, including DNA and proteins, leading to apoptosis, inflammation or cancer.

Consumer and environmental protection depend on the careful regulation of all classes of chemicals.

The ability to monitor analytes within physiological, environmental, and industrial scenarios is of prime importance in many scenarios.

With development of implants and in vivo detection devices comes the complication of the interaction between the materials used in the devices and biological fluids.

Nanocharacterisation provides an overview of the main characterisation techniques that are currently used to study nanostructured materials.

The coupling of mass spectrometry or nuclear magnetic resonance to chromatography has broadened the possibilities for determining organic reaction mechanisms.

The complexity and heterogeneity of biological systems has posed an immense challenge in recent years.

As a component of post-genome science, the field of proteomics has assumed great prominence in recent years.

The coupling of mass spectrometry or nuclear magnetic resonance to chromatography has broadened the possibilities for determining organic reaction mechanisms.

Electrochemical methods of chemical analysis have been widely used for many years, most especially the trusty pH electrode and conductivity meter, but also in the mass-manufactured glucose test strips which place electrochemical measurements into the hands of non-scientists.

Covering the latest developments in themes related to water disinfection by-products, this book brings the reader right up to date.

Incidents in the past have made scientists aware of the need for accurate methods of radionuclide analyses in order to estimate the risk to the public from released radioactivity.

Magnetic Resonance has become an established technique to improve the understanding of food systems.