Medicinal chemistry

This book describes the emergence and recent advances in the design and development of rhodium complexes as therapeutic agents.

This book reviews recent breakthroughs in anti-cancer drug discovery.

This book gathers the outcomes of several scientific events that were organized and conducted by the Institute of Scientific Communications (Volgograd, Russia) and the leading universities of the Volgograd region.

The book delves into the intricate realm of pharmacokinetics and pharmacodynamics as they apply to modern advancements in drug delivery systems.

The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes.

There have been major advancements in the pharmacologic treatment of eye diseases over the past decade.

The book presents a succinct summary of methods for the synthesis and biological activities of various different-sized bioactive heterocycles using different green chemistry synthetic methodologies, like microwave, ultrasonic, water mediated, ionic liquids, etc.

This book focuses on the principles, methods, and interpretation involved in establishing the safety, risk, and hazard assessment of small molecules.

Computer-Aided Drug Design (CADD) is a comprehensive guide designed for both beginners and experienced users in CADD.

This volume reviews the application of biochemical and molecular pathologies, which are based on conventional pathomorphology, toxicology, and DNA analysis technologies, not only to autopsies but also to the field of clinical medicine in general.

This book constitutes a key reference on the use of algae in the biopharmaceuticals production field; providing an updated outlook on the achievements accomplished thus far and transmitting a prospective view for this biotechnological application.

This book delves into the vital role of plants and their bioactive compounds in human health, emphasizing their medicinal and nutritional significance.

In the past decade, our understanding of the biochemistry, molecular biology, and neuropathology of the glutamate transporters and receptors has exploded.

This book illustrates numerous statistical practices that are commonly used by medical researchers, but which have severe flaws that may not be obvious.

Since the fortuitous discovery of its anticonvulsant activIty in 1962, valproate has established itself worldwide as a major antiepileptic drug against several types of epileptic seizures.

This book provides a detailed summary of the therapeutic benefits of natural extracts from medicinal plants, mushrooms, algae, fungi and sponges and their role in the prevention and treatment of obesity and diabetes, offering readers a solid introduction to obesity and diabetes as well as current treatment models.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

This book illustrates, in a comprehensive manner, the most current areas of importance to Safety Pharmacology, a burgeoning unique pharmacological discipline with important ties to academia, industry and regulatory authorities.

Translational medicine addresses the gap between research and the clinical application of new discoveries.

This book focuses on the different compounds (polyphenols, sterols, alkaloids terpenes) that arise from the secondary metabolism of plants and fungi and their importance for research and industry.

Disease-relevant intracellular protein-protein interactions occurring at defined cellular sites possess great potential as drug targets.

This book provides a compact and straightforward overview of the main concepts and applications of Pharmaceutical Biotechnology.

In this book, the author provides expert analysis on naturally occurring iridoids, their chemistry and their distribution in plants and insects.

Biological systems inherently possess much ambiguity or uncertainty.

This book provides a fundamental understanding of immunopathology and immunopathologic processes, with particular attention to nonclinical toxicology studies.

This book illustrates, in a comprehensive manner, the most crucial principles involved in pharmacology and allied sciences.

This book covers strategies to improve cell permeability, intestinal permeability, and metabolic stability, which are the typical liabilities associated with cyclic peptides, to enhance protein-protein recognition, and to build upon nature's cyclic peptides and macrocycles.

The concept of focal controlled drug delivery has been applied for treating illnesses that are localized to a certain tissue or organ.

This book provides a detailed summary of the therapeutic benefits of natural extracts from medicinal plants, mushrooms, algae, fungi and sponges and their role in the prevention and treatment of obesity and diabetes, offering readers a solid introduction to obesity and diabetes as well as current treatment models.

This volume comprises three reviews.

In spite of the enticing promises of the post-genomic era, the pharmaceutical world is in a state of disarray.

Through this monograph, the pharmaceutical chemist gets familiar with the possibilities electroanalytical methods offer for validated analyses of drug compounds and pharmaceuticals.

This volume provides readers with the basic principles and fundamentals of extrusion technology and a detailed description of the practical applications of a variety of extrusion processes, including various pharma grade extruders.

The book presents a multi-disciplinary approach to understanding mechanisms regulating the formation of mineral in vertebrate skeletal and dental tissues.

This book provides a comprehensive review of the literature available on satureja covering the ethnomedicine, micromorphology, the main secondary metabolites in its various species, as well it's important biological and pharmacological activities and the underlying mechanism of action for some of its medicinal properties.

Endophytes have unique characteristics to propagate inside host plants and aide the host by providing additional defense against environmental stresses and phytopathogens.

The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes - "e;Mechanisms and Models of Drug Interactions"e; and "e;Antimicrobial Drug Interactions"e;.

With the prospect of revolutionizing specific technologies, this book highlights the most exciting and impactful current research in the fields of cellulose-based superabsorbent hydrogels with their smart applications.

Since the first application of dendrimers in catalysis in the mid 1990s, this field has advanced rapidly.

There is a growing interest in unmet needs for the development of a new discipline in drug discovery and in university education on polypharmacology.

This book provides a comprehensive overview of the multifaceted field of protease in the cellular environment and focuses on the recently elucidated functions of complex proteolytic systems in physiology and pathophysiology.

This book presents a multidisciplinary assessment of the state of science in the use of systemic delivery technologies to deliver anti-aging therapeutics now under development.

This book provides a concise overview of recent advances in Pharmacokinetics (PK) and Pharmacodynamics (PD).

This textbook provides a comprehensive overview of the currently used concepts, approaches and technologies in the discovery and development of new treatments for the full spectrum of disorders of the central nervous system.

This book, now in an extensively revised second edition, describes the crucial role of zinc signaling in biological processes on a molecular and physiological basis.