Medicinal chemistry

Based on a fundamental understanding of the interaction between bacteria and materials, this timely volume emphasizes the latest research in the antimicrobial interfacial design and provides an invaluable blueprint for improving antimicrobial performance on devices and products.

This volume offers the most comprehensive coverage on fetal programming.

The author has summarized a decade of teaching combinatorial chemistry into this timely brief.

This book reviews the current state of ocular drug therapy and future therapeutic opportunities for a wide variety of conditions, including Age-related Macular Degeneration, Diabetic Retinopathy and Macular Edema, Glaucoma, and Inherited Retinal Diseases.

This book review series presents current trends in modern biotechnology.

The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds.

Medicinal chemistry is both science and art.

Proteins are exposed to various interfacial stresses during drug product development.

This volume assembles and integrates the wealth of diverse information that is now accumulating in this burgeoning field.

This volume provides a comprehensive overview of the hazards inherent in herbal medicinal products, with systematic coverage of major toxicities.

The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules.

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This volume consists of four chapters that cover a structurally diverse range of naturally occurring compounds.

A reference is needed that addresses the recent progress in aspects of PK/PD methods and developments of nanoparticles for novel drug delivery systems.

Medicinal chemistry is both science and art.

Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology.

Medicinal chemistry is both science and art.

This brief traces the story of one of our most common medicines - aspirin.

This book describes current understandings and recent progress into a varied group of natural products.

This book presents the proceedings of the 39th annual Midwest Biopharmaceutical Statistics Workshop (MBSW), held in Muncie, Indiana on May 16-18, 2016.

The book HSP70 in Human Diseases and Disorders provides the most comprehensive review on contemporary knowledge on the role of HSP70 family - one of the most studied HSP - in human diseases and disorders.

This volume builds upon the successful book Lanthanide Luminescence published in the Springer Series on Fluorescence in 2011.

Although the Bioequivalence (BE) requirements in many global jurisdictions have much in common, differences in certain approaches and requirements such as definitions and terms, choice of comparator (reference) product, acceptance criteria, fasted and fed studies, single and multi-dose studies, biowaivers and products not intended for absorption into the systemic circulation (locally acting medicines and dosage forms), amongst others, provide food for thought that standardisation should be a high priority objective in order to result in a harmonized international process for the market approval of products using BE.

This book explains theoretical and technological aspects of amorphous drug formulations.

This book addresses the therapeutic strategies to target mitochondrial metabolism in diseases where the function of that organelle is compromised, and it discusses the effective strategies used to create mitochondrial-targeted agents that can become commercially available drug delivery platforms.

The proposed book is envisioned for the nascent and entry-level researchers who are interested to work in the field of drug delivery and its applications specifically for macrophage targeting.

This volume discusses hazardous environmental micropollutants, their impacts on human health, and possible means to mitigate their associated risks.

Medicinal chemistry is both science and art.

The series "e;Clinical Approach and Procedures in Cosmetic Dermatology"e; intends to be a practical guide in Cosmetic Dermatology.

This is the first comprehensive reference compilation on the substance class of glucosinolates.

The eye is a computerized system that has been designed for self-defense, and these defense mechanisms create challenges in administration of medications to the eye.

This major reference work is a one-shot knowledge base on electroporation and the use of pulsed electric fields of high intensity and their use in biology, medicine, biotechnology, and food and environmental technologies.

This completely revised and updated second edition showcases the considerable progress that has taken place in this field since 2008.

This is the first of three volumes in the "e;Ion Channels & Transporters in Tumor Biology"e; collection, which discusses the function of ion transport proteins in cellular and systemic homeostasis.

The first book in the newly created book series, Computer-Aided Drug Discovery and Design, focuses on the computational aspects of early drug discovery, drug target identification, and validation.

Absorption, Distribution, Metabolism and Excretion (ADME) processes and their relationship with the design of dosage forms and the success of pharmacotherapy form the basis of this upper level undergraduate/graduate textbook.

This book deals with the recent advances in DNA-Encoded Library (DEL) technology that has emerged as an alternative to high throughput screening (HTS) over the last decade and has been heralded as a "e;disruptive"e; technology for drug discovery.

This book provides a comprehensive overview of the biosimilar regulatory framework, the development process and clinical aspects for development of biosimilars.

This book explores how nuclear magnetic resonance (NMR) spectroscopy may be used for spatial structural elucidation of novel compounds from fungal and synthetic sources.

This book summarizes the fast-growing and current knowledge about selenium interaction with cancer, diabetes, neuro-degeneration, heart disease, muscle disorders, HIV and several more.

Natural Products in the Chemical Industry is not a conventional textbook, but rather an invitation to join an entertaining journey that takes you into the fascinating world of natural products.

This invaluable resource discusses the current revolution in stem cell-based drugs and their potential use in clinical applications.

The first review describes examples of very promising compounds discovered from plants acquired from Africa, Southeast Asia, the Americas, and the Caribbean region with potential anticancer activity.

The purpose of this book is to give a concise introduction to development and analysis of pharmaceutical biologics for those in the pharmaceutical industry who are switching focus from small molecules to biologics processing, analysis, and delivery.

Unique work on structure-based drug design, covering multiple aspects of drug discovery and development.

This edited volume brings together the expertise of numerous specialists on the topic of particles - their physical, chemical, pharmacological and toxicological characteristics - when they are a component of pharmaceutical products and formulations.

This Reference Work is devoted to plant secondary metabolites and their evolutionary adaptation to different hosts and pests.

This timely volume explores the impact of autophagy in various human diseases, emphasizing the cell biological aspects and focusing on therapeutic approaches to these diseases.

Early anthropological evidence for plant use as medicine is 60,000 years old as reported from the Neanderthal grave in Iraq.