Chemistry

A comprehensive look at empirical approaches to molecular discovery, their relationships with rational design, and the future of both Empirical methods of discovery, along with serendipitous and rational design approaches, have played an important role in human history.

An all-in-one reference combining hydrodynamic theory with drilling applications for the design, planning, and optimization of drilling operations Hydromechanical processes underlie the majority of technology operations in drilling and present a crucial concern as the pace and depth of drilling increasesin today's energy-hungry world.

A consolidated and comprehensive reference on ligand-binding assays Ligand-binding assays (LBAs) stand as the cornerstone of support for definition of the pharmaco-kinetics and toxicokinetics of macromolecules, an area of burgeoning interest in the pharmaceutical industry.

A guide to using molecular biology and immunological methods for the analysis of food Many of the analytical problems that food chemists face in the lab cannot be solved by chemistry alone, and so analytical chemists are turning to molecular biology and immunology for alternative approaches.

A comprehensive resource on case studies of marketed kinase drugs and promising drug trials Since the discovery of protein kinase activity in 1954, the field of protein kinase drug discovery has advanced dramatically.

A comprehensive reference on nanoscale materials chemistry now revised and updated.

An unmatched reference on electrochemical technologies for soil, sediment, and groundwater pollution remediation Electrochemical technologies are emerging as important approaches for effective and efficient pollution remediation, both on their own and in concert with other remediation techniques.

A unique reference on peripheral pain receptor mechanisms While considerable advances have been made on pharmacotherapies for many chronic disease states, options available to treat chronic pain have remained relatively unchanged for decades.

The definitive compendium of bioassay procedures and applications A virtual encyclopedia of key bioassay protocols, this up-to-date, essential resource reviews the methods and applications of bioassays that quantify drug activity and evaluate the validity of pharmacological models.

A thorough survey of synthetic methods, chemistry, and applications of major classes of fluorinated heterocycles Merging organic, heterocyclic, and fluoroorganic chemistry, fluorinated heterocyclic compounds have distinctively desirable properties suitable for use in pharmaceuticals and agrichemicals, especially their ability to penetrate the cell membrane barrier for drug absorption.

Potassium chloride is a logical alternative to sodium chloride in water softening.

Use chemometric techniques to develop optimum separation conditions for capillary electrophoreses For all its advantages, capillary electrophoresis (CE) also carries significant disadvantages for the researcher.

Valuable information on corrosion fundamentals and applications of aluminum and magnesium Aluminum and magnesium alloys are receiving increased attention due to their light weight, abundance, and resistance to corrosion.

A collection of current knowledge of phytochemicals and health Interest in phenolic phytochemicals has increased as scientific studies indicate these compounds exhibit potential health benefits.

The science and applied approaches of enzyme inhibition in drug discovery and development Offering a unique approach that includes both the pharmacologic and pharmaco-kinetic aspects of enzyme inhibition, Enzyme Inhibition in Drug Discovery and Development examines the scientific concepts and experimental approaches related to enzyme inhibition as applied in drug discovery and drug development.

The third edition of the unparalleled reference on natural ingredients and their commercial use This new Third Edition of Leung's Encyclopedia of Common Natural Ingredients: Used in Food, Drugs, and Cosmetics arrives in the wake of the huge wave of interest in dietary supplements and herbal medicine resulting from both trends in health and the Dietary Supplement and Health Education Act of 1994 (DSHEA).

Expanding on the ideas first presented in Gerhard Ertl's acclaimed Baker Lectures at Cornell University, Reactions at Solid Surfaces comprises an authoritative, self-contained, book-length introduction to surface reactions for both professional chemists and students alike.

This valuable resource covers the principles of analytical instrumentation used by today's chemists and biologists and presents important advances in instrumentation, such as the drive to miniaturise and lab-on-a-chip devices.

Medicinal Chemistry: An Introduction, Second Edition provides a comprehensive, balanced introduction to this evolving and multidisciplinary area of research.

Crystal growth technology involves processes for the production of crystals essential for microelectronics, communication technologies, lasers and energy producing and energy saving technology.

The issue of quality assurance in the analytical chemistry laboratory has become of great importance in recent years.

This book provides an introduction to this exciting and relatively new subject with chapters covering natural and synthetic polymers, colloids, surfactants and liquid crystals highlighting the many and varied applications of these materials.

Providing an exhaustive review of this topic, Inorganic Mass Spectrometry: Principles and Applications provides details on all aspects of inorganic mass spectrometry, from a historical overview of the topic to the principles and functions of mass separation and ion detection systems.

Completely revised and updated, this text provides an easy-to-read guide to the concept of mass spectrometry and demonstrates its potential and limitations.

Spin Dynamics: Basics of Nuclear Magnetic Resonance, Second Edition is a comprehensive and modern introduction which focuses on those essential principles and concepts needed for a thorough understanding of the subject, rather than the practical aspects.

Carbodiimides play an important role as condensation agents in the synthesis of polypeptides, polynucleotides, polysaccharides and numerous other chemical transformations.

The analytical toxicologist may be required to detect, identify, and in many cases measure a wide variety of compounds in samples from almost any part of the body or in related materials such as residues in syringes or in soil.

Building on the foundation of the Second Edition, Symmetry and Structure: Readable Group Theory for Chemists, Third Edition turns the complex and potentially difficult subject of group theory into an accessible and readable account of this core area of chemistry.

Telomeres and TelomeraseChairman: Sydney Brenner, 1997 Telomeres are the protective genetic elements located at the ends of chromosomes and are essential for correct chromosomal structure and function.

The use of oligonucleotides as therapeutic agents rests upon their ability to interfere, in a sequence-specific manner, with the fundamental machinery of protein synthesis either by binding to the mRNAs transcribed from a gene or by binding directly to a target gene.

This up-to-the-minute account examines how radionuclides affect human health.

Degeneration of sensory receptors or of the nerves innervating them leads to a sensory deficit.

Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and pathology of elastin at the molecular level.

This book describes a diverse analysis of the five somatostatin receptors; somatostatin gene regulation; promatostatin processing; mechanisms of signal transduction; and the design and use of somatostatin analogues, including their possible clinical implications.

Experts in their respective fields present papers concerned with the range of human diseases caused by defective or abnormal functioning of cell adhesion molecules.

Renowned contributors provide comprehensive coverage of calcium gradients, waves and oscillations in diverse systems.

Prestigious contributors summarize current knowledge regarding the biosynthesis of tetrapyrrole pigments--chlorophyll, haem, vitamin B12.

A comprehensive review of current thinking on the biosynthesis, function and evolution of secondary metabolites in animals, plants and microorganisms.

A panel of internationally renowned experts present papers on cell signalling--an area in which there has been recent important advances.

Contains the presentations and discussions that took place during a symposium at the CIBA Foundation on October 1-3, 1990 on the subject of catalytic antibodies.

Composed of contributions from experts in the chemical and biological sciences, it explores host-guest molecular interactions leading to the formation of molecular assemblies containing two or more species.

Useful throughout history for their medical as well as other benefits, plant-derived compounds have gained particular importance recently, due to environmental factors.

Certain organic compounds can become toxic to biological tissue when activated by light.

Contributors to this volume explore the role of carbohydrates in communication between cells of multicellular organisms.

Comprises the proceedings of a symposium held at the Ciba Foundation, March 1988.

Regulation of intracellular pH is vital to all living cells.

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results.

This is the second edition of a unique book in the field of in vivo NMR covering in detail the technical and biophysical aspects of the technique.

The latest edition of a highly successful textbook, Mass Spectrometry, Third Edition provides students with a complete overview of the principles, theories and key applications of modern mass spectrometry.

An Introduction to Aqueous Electrolyte Solutions is a comprehensive coverage of the subject including the development of key concepts and theory that focus on the physical rather than the mathematical aspects.