Chemistry

In the first work to comprehensively cover this all-important topic, the recognized expert Helmut Vorbruggen provides both organic and bioorganic chemists with much new and valuable information for preparative synthesis.

This interdisciplinary approach combines the chemistry and engineering involved to describe the conception and improvement of chromatographic processes.

Here, authors from academia and industry provide an exciting overview of current production technologies and the fascinating possibilities for future applications.

Low-dimensional solids are of fundamental interest in materials science due to their anisotropic properties.

Edited by two of the experts in the field, the central aim is to show organic chemists working in process development that enantioselective catalysis is suitable for the large-scale production of enantioenriched intermediates.

Lipases and Phospholipases are key control elements in mammalian metabolism.

Peptides are among the most versatile bioactive molecules, yet the do not make good drugs, because they are quickly degraded or modified in the body.

This is the first book to describe the synthesis and characterization of the materials used in polymer-supported synthesis.

In most cases, every chemist must deal with solvent effects, whether voluntarily or otherwise.

Until now, the literature has offered a rather limited approach to the use of fundamental kinetics and their application to catalytic reactions.

The first volume in a new series dedicated to protein degradation, this book lays the foundations of targeted protein breakdown via the ubiquitin pathway.

The lock-and-key principle formulated by Emil Fischer as early as the end of the 19th century has still not lost any of its significance for the life sciences.

The demand for increasingly clean and efficient chemical syntheses is becoming more urgent from both an economic and an environmental standpoint.

The vast progress made in the investigation of biomolecules using NMR has only recently been rewarded with the Nobel Prize for Kurt Wuthrich.

Magnetic phenomena and materials are everywhere.

From reviews of the previous volumes: 'This is an essential book for researchers in electrochemistry; it covers areas of both fundamental and practical importance, with reviews of high quality.

While this important reaction class is among the most important and most widely used in organic chemistry, this is the first book to summarize the many different olefination methods, including: * Wittig reaction * Peterson reaction * Julia olefination * Utilizing the Tebbe and related reagents * Low-valent chromium, zinc or titanium mediated olefination * McMurry coupling plus the related reactions in each case and the application to asymmetric synthesis.

Micro process engineering is approaching both academia and industry.

The demand for increasingly clean and efficient chemical syntheses is continuously becoming more urgent from both an economic and an environmental standpoint.

The miniaturization of bulky devices and machines is a process that confronts us on a daily basis.

Computational methods are transforming the work of chemical and pharmaceutical laboratories.

In light of the increasing importance of these proteins and their ligands for our understanding of cellular growth, differentiation, and development, as well as of diseases such as obesity, insulin resistance, atherosclerosis, cancer, and inflammation, a team of internationally renowned editors and authors have compiled here the very first comprehensive book on these topics.

At the start of the 1950s, Ziegler and Natta discovered that simple metallorganic catalysts are capable of transforming olefins into linear polymers with highly ordered structures.

Electron spin resonance spectroscopy is the method used to determine the structure and life expectancy of a number of radicals.

Interest in nanoporous crystals as host-guest systems has risen dramatically over the past few years, such that this fascinating class of substances now plays an important role not only in material sciences, but also in numerous other disciplines, such as organic or supramolecular chemistry.

The peroral application (swallowing) of a medicine means that the body must first resorb the active substance before it can begin to take effect.

In the chemical industry, just in time delivery and ever more efficient processes are prime requisites for competitiveness.

Leading experts from all over the world present an overview of the use of enzymes in industry for: - the production of bulk products, such as glucose, or fructose - food processing and food analysis - laundry and automatic dishwashing detergents - the textile, pulp and paper and animal feed industries - clinical diagnosis and therapy - genetic engineering.

Most syntheses in the chemical research laboratory fail and usually require several attempts before proceeding satisfactorily.

The formation of solids is governed by kinetic processes, which are closely related to the macroscopic behaviour of the resulting materials.

Here, more than 20 experts from leading research institutes around the world present the entire scope of this rapidly developing field.

This first complete resource on photosensory receptors from bacteria, plants and animals compiles the data on all known classes of photoreceptors, creating a must-have reference for students and researchers for many years to come.

Based on the very successful German editions, this English version has been thoroughly updated and revised to reflect the developments of the last years and the latest innovations in the field.

At the very latest, with the award of the 2001 Nobel Prize for work on asymmetric oxidation, there has been a need for a comprehensive book on such methods.

Miniturization and high throughput assay technology have brought the power of molecular evolution to the bioscience laboratory.

Now over 50 % new contents.

A deeper insight into the complex processes involved in this field, covering the biological, chemical and engineering fundamentals needed to further develop effective methodologies.

Toxicogenomics is a new, dynamic and very promising field that can help optimize toxicity analyses and streamline research into active substances.

Combining the contemporary knowledge from widely scattered sources, this is a much-needed and comprehensive overview of the field.

Edited by the leading experts John Gladysz, Dennis Curran, and Istvan Horvath, this handbook is the first to summarize all the essential aspects of this emerging field of chemistry.

Adopting a practical approach, the authors provide a detailed interpretation of the existing regulations (GMP, ICH), while also discussing the appropriate calculations, parameters and tests.

A very detailed, workable approach to improving energy efficiency and cost effectiveness in petroleum processing, dealing with the role of management and refinery operators in achieving the best technological parameters, the most rational utilization of energy, as well as the greatest possible economic success.

This laboratory guide for successful electrophoretic separations is divided into two parts to provide readers with a thorough presentation of the fundamentals followed by a detailed description of the most common methods currently in use.

A comprehensive and up-to-date overview of the major mineral and organic fillers for plastics, their production, structure and properties, as well as their applications in terms of primary and secondary functions.

This hands-on guide to RNA interference brings the power of targeted gene silencing to any laboratory with the basic equipment for handling nucleic acids.

Current interest in research of solidification of melts is focussed to understand crystal nucleation and crystal growth.

This first book to comprehensively cover this hot topic presents the information hitherto scattered throughout smaller reviews or single book chapters to provide an introduction to this rapidly expanding field.

In this first book to cover model systems, molecular mechanisms and clinical trials all in one volume internationally renowned scientists and clinicians provide a comprehensive treatment of neuroprotective strategies for all important neurological disorders.

In this first book to present every important aspect of this fascinating and developing field, the three editors A.

Organonickel chemistry plays an increasingly important role in organic chemistry, and interest in this topic is now just as keen as in organopalladium chemistry.