With the beginning of the 1980's it was becoming increasingly evident that the lack of approval of new cardiovascular agents for use by clinicians in the United States for the treatment of cardiovascular disorders was becoming a problem.
The thrust here is for those who want to know more than the answer to an exam question - an approach to disease diagnosis and treatment which emphasizes thoughtful consideration of alternatives, finding ones way through uncertainties and lack of knowledge.
In the denervated state the mammalian heart, both in vivo and in vitro, is excited at very regular intervals, the coefficient of variance of the interbeat intervals not exceeding 2%.
Patients currently experiencing acute myocardial infarcts are the beneficiaries of information gathered during the 80 years since this clinical phenomenon was described and the 20 years since treatment in coronary care units was introduced.
The extension of conventional M-mode to two-dimensional echocardiography has been a major advance for the evaluation and management of cardiac disease.
It is not often that one one writes the foreword for a book based on a conference which contributed so much to our knowledge in the field of hypertension.
In the thirty years since the advent of efTective pharmacologic treatment for hypertension, the world ofthe hypertensive has been transformed beyond recog- nition.
2 The free internal Ca+ concentration in human red cells is set according to the leak- 2 and-pump principle: There is a finite passive Ca+ influx at the physiological 2 2 Ca+ -gradient across the membrane which is compensated by Ca+ pumping in the outward direction with a rate given by the degree of saturation of the A TP-fuelled Ca- 2 pump at the steady-state internal Ca+ concentration.
In a relatively short period of time two-dimensional echocardiography has become the most important non-invasive diagnostic tool in the daily practice of a pediatric cardiologist who predominantly deals with congenital structural heart disease in neonates and infants.
This book contains the manuscripts of the majority of the papers given during the symposium 'Improvement of Myocardial Perfusion' which was held from Sep- tember 27-29,1984 in Mainz/Germany.
In any textbook, basic scientific knowledge, and the art of clinical practice should be brought together in a rational manner and this volume on cardio- vascular therapy attempts to achieve this aim.
Twenty five years ago, cardiomyopathies or myocardopathies as they were sometimes called, were in very small print, and often the terms myocarditis and cardiomyopathy were used interchangeably.
This book is designed as a definitive report on current capabilities of ultrasound imaging and Doppler evaluation of the cerebral circulation, both extracranial and intracranial.
In the last 15 years we have had the opportunity to teach Electrocardiography to many different types of student: doctors preparing to become cardiologists, cardiologists attending weekly 'refresher' sessions at our hospital, general practitioners who wish to become adept at electrocardiography and attend our yearly courses and, finally, the medical students of the Universidad Aut6noma of Barcelona.
Since the introduction of coronary angioplasty in 1977, this procedure has gained a steadily increasing position in the treatment of coronary artery obstmction.
In recent years considerable progress and new developments in diagnostic and interventional cardiology have been observed, such as balloon angioplasty of coronary artery stenoses, reperfusion techniques in acute myocardial infarction, new pacing, and cardioversion-defibrillation techniques in ventricular tachyar- rhythmias.
Over the past twenty years, technical advances in coronary arteriography have contributed to our understanding of the pathophysiologic aspects and natural history of coronary artery disease.
Participation in athletics at both the recreational and competitive levels has grown enormously over the last decade, and now involves a substantial segment of the population of many countries, particularly those in Europe and North America.