Immunology

With the increasing use of immune checkpoint inhibitors (ICI) across various cancers, the trends for indication at earlier stages, and the use of combination immunotherapy, the frequency of ICI-induced immune-related adverse events (irAE) is expected to grow substantially.

Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology.

Bioinformation Discovery illustrates the power of biological data in knowledge discovery.

From the 39th annual conference of the International Society on Oxygen Transport to Tissue (ISOTT), held in Washington, DC, USA in July 2011, this volume covers aspects of oxygen transport from air to the cells, organs and organisms; instrumentation and methods to sense oxygen and clinical evidence.

As our understanding of immune mediated chronic inflammatory diseases (IMIDs) grows, it becomes more and more clear that these conditions result from the convergence of a multitude of pathogenic mechanisms whose relative individual contribution is different in different patient subsets.

TLR4 is one of the most important innate immunity receptors, its function mainly consisting in the activation of inflammatory pathways in response to stimulation by Pathogen-Associated Molecular Patterns (PAMPs) and Damage Associated Molecular Pattern molecules (DAMPs).

Currently, malaria kills more than 300,000 people per year, making it a top priority of world leaders and international organizations, who are working towards implementing and coordinating efforts to eradicate this disease.

This PIR volume presents a comprehensive collection of reviews that focus on the role of the blood-brain barrier (BBB) during steady-state and inflamed conditions.

This book provides detailed information on the nosology, pathology, pathogenesis, clinical presentation, diagnosis and treatment of fibro-inflammatory disorders, rare diseases that often display systemic organ involvement.

Phagocytosis is the engulfment of particulate matter by cells.

 Antimicrobial resistance is now a general problem.

This book examines Au (I, III) complexes that selectively attack and inhibit zinc finger proteins (ZnFs) for potential therapeutic use.

This volume focuses on the laboratory and clinical experience with targeting viral onco-antigens, while also reviewing the approaches to targeting self-cancer antigens in cancers of non-viral origin, where self-tolerance has been a challenge.

A comprehensive overview of the current research on inflammation and immunopharmacology, with particular attention to the use of anti-inflammatory drugs, this book discusses future trends in this area of pharmacological research.

A follow-up to Emerging Issues and Controversies in Infectious Diseases, this volume provides a comprehensive review of topical issues in infectious diseases, highlighting the controversies related to the newest findings and recommendations.

Perinatal psychiatry is an emerging field that investigates the role of perinatal events - for example pregnancy complications and infections - in the development of neuropsychiatric conditions, such as schizophrenia and mood disorders.

This book covers the latest information related to understanding immune responses to engineered nanomaterials (ENMs).

Multiple Sclerosis (MS) is one of the main causes of disability in young adult population.

This book provides up-to-date information on immunogenetics of fungal diseases in the context of primary and acquired immunodeficiencies.

Various "e;omics"e; methods have recently revolutionized molecular diagnostics.

This book provides an essential update on the startling array of novel insecticidal toxins and drugs produced by the fascinating bacterium Photorhabdus.

Herpes viruses are widely distributed in nature, causing disease in organisms as diverse as bivalves and primates, including humans.

This book addresses the biological processes relevant to the immune phenotypes of cancer and their significance for immune responsiveness, based on the premise that malignant cells manipulate their surroundings through an evolutionary process that is controlled by interactions with innate immune sensors as well as the adaptive recognition of self/non-self.

This second edition of Clinical Use of Anti-Infective Agents provides a comprehensive overview of current approaches to using drugs to treat infections, including historical perspectives, definitions, and discussion of pharmacokinetics and pharmacodynamics and their uses.

This book integrates topics in basic research and clinical medicine as well as molecular and cell biology.

This book focuses on the fundamentals of the use of biologics in asthma, describing the rationale, principles, mechanisms of action, and indications.

The book Heat Shock Proteins in Inflammatory Diseases provides the most comprehensive highlight and insight of the expression, function and therapeutic activity of Heat Shock Proteins in inflammatory diseases including sepsis, psoriasis, neurodegenerative diseases, cancers, viral infection and autoimmune rheumatic diseases.

This ?

This book serves as a comprehensive but concise, practical, in-depth resource for practitioners who see and treat anaphylaxis.

This book presents detailed state of the art knowledge on the humoral primary immunodeficiencies (PIDs), i.

This research volume examines the available alternative, complementary, pharmaceutical and vaccine methods for treating, mitigating, or preventing COVID-19.

This book provides a detailed overview of the activity and efficacy of new treatments and promising perspectives in the field of cutaneous malignancies.

This book is designed to re-establish the position of the oral cavity and its mucosa at the forefront of defence and maintenance of homeostatic mechanisms that protect against disease not just locally but also systemically.

In order to understand common conditions such as coeliac disease and Crohn's disease, one must view the gut in its evolutionary context.

This volume gives a state-of-the-art overview on macrophage functions in various invertebrate and vertebrate systems and diseases.

Mit diesem Praxisbuch können klinisch tätige Neurologen über die aktuellen therapeutischen Strategien in der Neuroimmunologie und in den Nachbardisziplinen informiert bleiben.

Revealing essential roles of the tumor microenvironment in cancer progression, this book focuses on the role of hematopoietic components of the tumor microenvironment.

This volume provides an overview on the influence of Extracellular Matrix (ECM) on tumor progression.

This book provides a comprehensive overview of the biology of the endoplasmic reticulum (ER) and the associated ER proteins, it discusses their structure, function and signaling mechanisms in the cell and their role in disease.

This book summarizes recent advances in antibody glycosylation research.

Multiple Myeloma remains an incurable malignancy.

Plasmodium falciparum malaria is responsible for the deaths of nearly 500,000 people each year.

This volume reviews the current research focused on the functional importance of unfolded protein response (UPR) signaling in the context of health and disease.

This book combines fundamental concepts of biochemistry and the dental sciences to provide an authentic, coherent and comprehensive text for dental students.

Lymphatic Filariasis (LF) is a group of human and animal infectious diseases caused by nematode parasites of the order Filariidae.

This book addresses the molecular mechanisms of food allergies and related control strategies.

In this book, expert dermatologists review state of the art knowledge concerning the clinical presentation and management of cutaneous diseases that develop in immunosuppressed individuals.

In dem wissenschaftlichen Sachbuch erklärt der Rheumatologe und Professor für experimentelle Medizin Rainer H.

This book presents the latest breakthrough results in glycobiology regarding the roles of glycans in relation to quality control and transport of protein, the immune system, viral infection, stem cells, the neural system, and various diseases such as cancer, diabetes, chronic obstructive pulmonary disease, muscular dystrophy, and schizophrenia.