The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1?
This book deals with the advantages of using artificial intelligence (AI) in the fight against the COVID-19 and against future pandemics that could threat humanity and our environment.
This book fills the need for a simplified text covering western blotting protocols aimed not just at high school and college students, but the researcher with little to no experience in these techniques.
In this book, leading experts in cancer immunotherapy join forces to provide a comprehensive guide that sets out the main principles of oncoimmunology and examines the latest advances and their implications for clinical practice, focusing in particular on drugs with FDA/EMA approvals and breakthrough status.
This volume focuses on IgG4-related disease (IgG4-RD), a novel clinical entity involving multiple organs and of unknown origin, associated with the abundant infiltration of IgG4-positive cells.
This book provides a broad clinical overview of primary and secondary immunodeficiencies nested in clinical cases that will help the reader understand the approach to evaluation, diagnosis, and management of these challenging cases.
This book focuses on the salient features of the biology of Bone Morphogenetic Proteins and the advances in our understanding of their structure and function and of downstream signaling, as well as their governance in systems biology from bone and dentin to kidney, cancer, diabetes, iron homeostasis and angiogenesis, including rare musculoskeletal disorders.
Our own experience shows that there is no simple, yet of good scientific and clinical quality guide for practitioners and patients on gastrointestinal diseases.
This book provides a fundamental understanding of immunopathology and immunopathologic processes, with particular attention to nonclinical toxicology studies.
Experts from around the world review the current field of the immunobiology of heat shock proteins, and provide a comprehensive account of how these molecules are spearheading efforts in the understanding of various pathways of the immune system.
This edited collection of 12 chapters by research workers from a wide range of disciplines resolves the confusion that currently surrounds the "e;hygiene hypothesis"e; by considering the human need for exposure to microorganisms from an evolutionary point of view.
This comprehensive book thoroughly covers the field of stinging insect allergy; addressing all clinical aspects, including diagnosis and therapeutic recommendations.
This book provides a fundamental understanding of immunopathology and immunopathologic processes, with particular attention to nonclinical toxicology studies.
This book covers all aspects of hypersensitivity to drugs, providing practical information for non-specialist physicians as well as addressing issues of interest to practitioners in different specialties and presenting the expert knowledge required by specialist allergists and immunologists.
This book gathers international knowledge and contemporary clinical and scientific evidence on infections associated with the musculoskeletal system at a time when we are confronted with significant challenges and uncertainty.
The present book intends to provide an update on immunosenescence and how deficiencies in the immune system contribute to a higher susceptibility to infections, decline in organ function, reduced vaccination responses, age-related disease and the ageing process itself, negatively affecting longevity.
Accelerated Path to Cures provides a transformative perspective on the power of combining advanced computational technologies, modeling, bioinformatics and machine learning approaches with nonclinical and clinical experimentation to accelerate drug development.
This book presents advanced therapies based on new and complementary drugs, and alternative techniques and strategies, such as phages, probiotics, flavonoids, essential oils, cellulose, peptides, nano delivery, iron starvation and vaccines.
This book focuses on C-type lectin receptors, a newly emerging family of pattern-recognition receptors (PRRs) and a crucial part of the human innate immune system.
This book presents detailed case reports of unusual diseases with common symptoms, many of which have emerged in the past decade as a result of nature, advances in medical treatment, and increasing recognition of specific underpinnings of human biology and immunology.
More than fifty years after its initial discovery by Rita Levi Montalcini and Stanley Cohen and the proposal of the neurotrophic theory, nerve growth factor (NGF) has become the prototype of a family of biologically active molecules called neurotrophic factors (NTFs).
This textbook aims to describe in a condensed form the essentials of molecular immunology behind bacterial infections, the microbiome, viral infections (such as influenza and COVID-19), organ transplantations, autoimmunity, allergy and tumor immunology.
This volume on Rarer Arthropathies, part of the series "e;Rare Diseases of the Immune System"e; aims to fill a gap in the literature by informing and updating clinicians on the unusual and uncommon forms of arthritis and related musculoskeletal conditions.
This book provides an essential overview of the role of phosphoinositide-3-phosphate kinase (PI3K) isoforms in modulating the function of immune system cells and their involvement in disease.
This volume will serve as a comprehensive and useful guide for ENT physicians in the recognition, diagnosis, and treatment of patients who suffer from sinus headaches and migraines.
This textbook provides a comprehensive overview of the state of the art in otolaryngology, discussing all the newly advances in the subspecialties of head and neck, plastics, otology, laryngology, rhinology and pediatrics, and also addressing topics like allergy, sleep medicine, trauma, and the fundamentals of systemic diseases that frequently manifest in the head and neck region.
