This book provides detailed information on the nosology, pathology, pathogenesis, clinical presentation, diagnosis and treatment of fibro-inflammatory disorders, rare diseases that often display systemic organ involvement.
In the current edition, Selenium: Its Molecular Biology and Role in Human Health expands extensively on the previous editions providing readers with the most significant advances in the rapidly developing selenium field.
This well-illustrated quick reference book, now in its second edition, is a comprehensive guide to the aquatic skin diseases caused by biotic and non-biotic noxae.
In spite of their relatively low prevalence, systemic vasculitides have been the object of intensive basic and clinical investigations over the last few years.
This fully updated and extended second edition provides a comprehensive overview on the basic concepts of the rapidly developing field of osteoimmunology and also offers in-depth insights into the molecular mechanisms of bone diseases.
The book describes the major degenerative processes and pathologies exacerbated by senescence and how they can be alleviated through retardation of cellular aging.
This book provides an expert summary of autophagy, a relatively new but rapidly expanding field of biomedical science with important implications in health and disease.
This book offers an overview of our current understanding of host defense peptides and their potential for clinical applications as well as some of the obstacles to this.
Aimed at both beginners and experienced researchers unfamiliar with the technique, this book provides a concise and easy-to-understand guide to using immunohistochemistry.
The concept of immunotherapy was in infancy when the first edition was written; since then, major advances have been made, not only with several prominent clinical trials, but also with the approval of cell-based therapy by the FDA for the treatment of cancer in 2010.
This updated volume provides a "e;user-friendly"e; reference for dermatologists, dermatology residents and students, as well as for health care workers in related fields to better understand immune-mediated skin diseases and their therapies.
As the number of patients undergoing hematotopoietic or solid organ transplantation increases, a deep understanding of the field of transplant infectious diseases grows increasingly vital.
Oxidation of polyunsaturated fatty acids by lipoxygenases leads to a variety of fatty acid metabolites which play important roles in physiology but also in pathophysiology.
This book describes the structures of Metallothionein (MT) family members and the cellular functions of MT-1, MT-2 and MT-4 isoforms, as well as provides insights into divergent biological roles of MT-3.
The book starts with an introduction to and history of myeloid-derived suppressor cells (MDSCs), followed by a description of their differentiation, their role in the tumour microenvironment and their therapeutic targeting.
This volume covers the topics presented at the 3rd International Conference on Tumor Microenvironment and Cellular Stress by an international community of researchers.
Over the past decade, we have made great advances in the field of multiple sclerosis (MS) research, and this book focuses on those advances in MS pathogenesis and treatment.
This book reviews the chemical and biological properties of Artemisia amygdalina Decne, a critically endangered and endemic plant species in the the high-altitude Kashmir Himalayas, which has a high pharmacological potential.
In this volume devoted to systemic lupus erythematosus (SLE) and Sjogren syndrome, leading specialists from different disciplines present the latest research findings on many aspects of the diseases and describe the most recent trends in treatment, such as the "e;treat to target"e; approach.
Tocelebrate the 40th anniversary of the discovery of Natural Killer (NK) cells,this volume focuses on the recent advances in our understanding of NK cell developmentand differentiation and their acquisition of functional properties, as well asthe latest models for NK-cell analysis in mice and applications in clinicalmedicine.
This volume focuses on apoptotic and non-apoptotic programmed cell death, including necroptosis, pyroptosis, and ferroptosis, and presents recent findings in the field.
This volume focuses on the laboratory and clinical experience with targeting viral onco-antigens, while also reviewing the approaches to targeting self-cancer antigens in cancers of non-viral origin, where self-tolerance has been a challenge.
This volume brings together recent developments in quasispecies theory extended to variable environments and practical applications in elucidating viral dynamics and treatment designs.
This book provides an updated overview of agammaglobulinemia, a rare form of primary immunodeficiency which is considered the prototype of the congenital humoral defects, and which is characterized by the absence of peripheral B cells and very low serum immunoglobulin levels.
This book sheds new light on clinical, biological and therapeutic data on the rare disease Waldenstrom's Macroglobulinemia (WM) with the participation of widely-recognized experts, involved in this field.
This book presents the state of the art in research into atopic dermatitis, or atopic eczema, and provides numerous effective practical management recommendations that are grounded in the immense clinical experience of the author.
This book discusses recent advances in new anti- and pro-inflammatory pathways in diabetic disease, and identifies new diagnostic immunological methods that offer potential companion diagnostics for diabetic diseases.
Head and neck squamous cell carcinoma (HNSCC), the sixth most prevalent cancer worldwide, remains a very difficult disease to treat and cure despite intensive investigation into molecular etiologies and tumor progression pathways.
