Diseases and disorders

This book summarizes the potent effect of ultraviolet radiation (UVR) on the photoaging and cancer formation.

This book aims to provide readers with a sound understanding of the spectrum of radiologic appearances of bone tumors, which reflect histopathology, and the pattern analysis of imaging findings.

This book examines the utility of genome-wide association studies (GWAS) in the era of next-generation sequencing and big data, identifies limitations and potential means of overcoming them, and looks to the future of GWAS and what may lay beyond.

This volume explores the latest methods used by researchers to study different trypanosomatid parasites.

This third edition aims to provide new and updated methods on animal influenza viruses as well as more advanced protocols that will guide the reader in designing research.

This volume details practical procedures on the latest DNA vaccine technology.

This detailed book showcases the tremendous effort and progress made in developing techniques and protocols for the study of immunometabolism, and in utilizing recent technological advances for probing and manipulating adipose and immune cells, and subsequently, their functions and immunometabolic consequences.

This volume looks at all aspects of manipulation of Leptospira spp.

This volume focuses on various methods used by researchers to study mucosal-associated invariant T (MAIT) cells in the aspects described below.

This volume provides methods and techniques to further the study of cancer immunoprevention.

This second edition provides an overview of recent developments and approaches used by researchers to investigate the properties and functions of mammary epithelial and stem cells, which will contribute to understand the heterogeneity of the mammary gland and of breast cancer.

This detailed volume explores methods and techniques reflecting how viruses can be a beneficial force for all levels of life as well as the mammalian microbiota.

Antimicrobial resistance will become a global health threat since antimicrobial treatments continue at the forefront of the defense against microbial infections.

This detailed volume provides a robust set of methods to understand variation between patients with ovarian cancers, in vitro models to better study different stages of the disease, and in vivo models to test therapies.

This new edition explores lab protocols describing new techniques to study cytotoxic T-cells (CTLs), as well as chapters of a more general discursive nature, all with an emphasis on the use of systems biology in immunology.

This detailed book serves as a systematic examination of the analytical methods to study the transcription factor NF-[kappa]B in physiology and disease.

This detailed volume presents status and management protocols with the objective of identifying proper guidelines and materials for research related to the most common malignant neoplasm in the thyroid gland, papillary thyroid carcinoma.

This detailed volume explores various aspects of the dengue virus and its four serotypes (DENV1-4).

This book serves to introduce the technologies and applications of precision medicine.

This detailed book serves as a laboratory manual containing vital protocols and in-depth discussion involving commonly used experimental approaches for the characterization of several aspects of lung tumor biology.

This third edition expands upon the previous edition with current, detailed methods on different aspects, and landmarks advancing knowledge on Salmonella research.

This detailed volume presents a variety of animal models that are commonly used to study sepsis and some key procedures to measure specific disease outcomes.

This volume provides a practical guide providing step-by-step protocol to explore vaccines for farm and companion animals, as well as for fish and insects.

This detailed book explores the technical breakthroughs with biophysical and cell biological approaches that have advanced the study of molecular mechanisms underlying the generation and transduction of the hedgehog (HH) signal, indicating the important role of sterols in this pathway.

This book describes the biology, diagnosis, treatment and the latest research on anti-sperm antibody (ASA) and anti-zona pellucida antibody (AZPA) produced in some infertile patients.

This volume provides current management and research protocols on oesophageal squamous cell carcinoma.

This detailed book focuses on various aspects of Invariant Natural Killer T-Cells (iNKT), which are known to contribute to homeostasis and autoimmunity and can also cause various pathological responses such as allergy, infection, excessive autoimmune response, and cancer.

The detailed volume aims to provide a comprehensive hands-on manual covering all the techniques involved in the cellular and molecular identification and characterization of both normal hematopoietic and leukemic stem cells, both from human patients and from mouse models of human leukemia.

This volume provides an updated collection of protocols for manipulating and studying VEGF signaling pathways in vitro and in vivo and aims to present a range of both firmly established and newly emerging technologies.

This volume explores the latest techniques used to study Mycobacterium ulcerans, and more specifically M.

This volume provides a practical guide providing step-by-step protocol to design and develop vaccines for human diseases.

This volume provides a comprehensive reference guide for researchers to study the applications of labeled antibodies.

This text provides a practical guide providing step-by-step protocol to design and develop vaccines.

This extensive volume covers basic and advanced aspects of peptide antibody production, characterization and uses.

This volume shares technologies that detect common epigenetic changes which are very important in the early detection, progression, and prognosis of cancer as well as the design of new therapeutic tools against cancer cells.

This volume discusses the latest protocols used by scientists to understand ZIKV and how to mitigate its presence.

In Basophils and Mast Cells: Methods and Protocols, experts in this challenging field explore techniques to research these cells from the most practical point of view.

This extensive book brings together leading melanoma researchers from across the world and highlights many of the cutting-edge protocols and experimental systems currently being used to investigate questions surrounding this disease.

Focused on the discovery of precise molecular targets for the development of the cancer preventive agents, Cancer Prevention: Dietary Factors and Pharmacology provides researchers and non-researchers with practical methodologies for developing and validating small molecule and phytochemical-derived drug discovery and mechanisms by which these compounds can modulate distinct target proteins involved in oncogenic signaling.

Diverse molecular, cellular, and environmental events must all come together to allow the successful formation of secondary cancers, metastases.

This second edition volume expands on the previous edition with descriptions of recent developments in the field.

This collection explores state-of-the-art methods and protocols for research on photodynamic therapy (PDT) and its use in a wide range of medical applications, from antiviral to anticancer.

This volume focuses on malaria vaccinology, and introduces researchers to a complete overview of the protocols and tools used by molecular and cellular malariologists.

Avian Influenza Virus, Second Edition aims to provide the essential methods used in working with animal influenza viruses, and to compile more advanced information that will guide the user in designing influenza studies.

This volume looks at in vitro disease models representing the respiratory, hepatobiliary, osteochondral, nervous, dermal, ocular, immune system, and pathological biological processes like tumorigenesis for stem cell research.

This volume highlights the molecular and cellular methods used in studying Chronic Myeloid Leukimia (CML) pathogenesis and stem cell biology.

This volume provides current and new advanced methods and protocols to study T cells.

This book describes the most important techniques used for studying cfDNA in the different samples; serum, plasma, urine.

The volume provides a comprehensive overview of methods that have been developed for the study of Tfh and Tfr biology in mice, and in different human diseases.

This volume covers methods for determination of autoantibodies in rheumatic connective tissue diseases and organ-specific diseases.