Monoclonal Antibodies: Methods and Protocols examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting with opening chapters focusing on the gold standard method for generating mouse monoclonal antibodies through hybridoma technology, future methods for engineering recombinant and humanized antibodies, methods for engineering soluble Fc fusion protein, and the use of antibodies and flow cytometry in the quantification of cell signaling proteins.
This second edition volume expands on the first edition with new developments on Toll-Like Receptors (TLRs) controlling events such as cross-priming of associated pattern recognition receptors, post-transcriptional regulation, interaction with other cellular and biologic systems, and cancer progression.
This comprehensive book presents the latest information on all aspects of the aging skin, including a broad spectrum of the relevant basic science, malignant and non-malignant age-associated diseases and conditions, techniques and methods, toxicological and safety considerations in the elderly, psychological and social issues, ethnicity and gender differences and marketing to the aged.
Part I covers modern advances in the determination ofglycoprotein structure and in the biosynthesis of mammalian,bacterial, yeast, plant and insect glycoproteins.
Adenovirus Methods and Protocols, Second Edition, now in two volumes, is an essential resource for adenovirus (Ad) researchers beginning in the field, and an inspirational starting point for researchers looking to branch into new areas of Ad study.
A collection of state-of-the-art molecular methods for studying antifungal resistance, for discovering and evaluating both new and existing antifungal drugs, and for understanding the host response and immunotherapy of such agents.
Cancer Genomics and Proteomics: Methods and Protocols provides a compendium of techniques and applications that will be of profound use to researchers interested in gene identification and function.
This volume reviews available mouse models of atherosclerosis, basic aspects of disease initiation and progression, and the visualization of atherosclerotic lesions with invasive and non-invasive techniques that are widely used both in basic research and in the clinic.
Recent outbreaks of swine influenza and avian influenza, along with the remaining and in some cases expanding threats from HIV, dengue virus, and the viruses causing hepatitis, have reinforced the need for rapid, accurate and cost-effective diagnosis of viral disease.
The aim of this book is to provide detailed protocols for studying the molecular biology of the pathogen Mycobacterium tuberculosis, and its int- actions with host cells.
Essential knowledge and advanced insights for otolaryngology practiceNow in its fully revised and updated 4th edition, Ear, Nose, and Throat Diseases: With Head and Neck Surgery remains a trusted reference for medical students, residents, and specialists.
Metabolites as Signals in Immunity and Inflammation describes the revolution in the definition of the word metabolism, highlighting changes in thinking about the whole field of immunology.
Antibody-drug conjugates (ADCs) represent a promising therapeutic approach for cancer patients by combining the antigen-targeting specificity of monoclonal antibodies (mAbs) with the cytotoxic potency of chemotherapeutic drugs.
Health literacy is a critical skill for engaging in healthy behaviors to reduce disease risk and improve health outcomes across the continuum of cancer care.
The sustained skin research efforts over the past decades has led to the accumulation of a significant collection of information on skin structure and physiology as well as on the pathogenesis of cutaneous diseases.
This volume shares technologies that detect common epigenetic changes which are very important in the early detection, progression, and prognosis of cancer as well as the design of new therapeutic tools against cancer cells.
Das knackig formulierte und praxisnahe Übungsbuch mit Fallbeispielen und zahlreichen mikroskopischen Bildern stellt die optimale Vorbereitung auf die Facharztprüfung in der Hämatologie dar.
In December 2019, new cases of severe pneumonia were first detected in Wuhan, China, and the cause was determined to be a novel beta coronavirus related to the severe acute respiratory syndrome (SARS) coronavirus that emerged from a bat reservoir in 2002.
Since the publication of the popular first edition, genomic methods have become more accessible, allowing antibiotic researchers to probe not only the sequence of antibiotic resistance determinants but the mechanism whereby they are expressed and regulated.
Lymphomas are lymphoid malignancies derived from B or T lymphocytes, and their study has been and still is paradigmatic for many aspects of cancer research.
En esta obra se presentan temas de neurología, como isquemia cerebral transitoria y delirium; de endocrinología, como diabetes mellitus, insuficiencia suprarrenal y dislipidemia; de cardiología, como síndrome coronario agudo y fibrilación auricular; de neumología, como neumonías, enfermedad pulmonar obstructiva crónica y tromboembolia pulmonar; de gastroenterología, como diarrea por Clostridium difficile, cirrosis descompensada y enfermedad ácido-péptica; de nefrología, como lesión renal aguda, hipertensión arterial e hiponatremia; de hematología, como anemia; de infectología, como enfermedades transmitidas por mosquitosAede.
This book provides an in-depth look into the application of cancer vaccines in the treatment of cancer, which is being enhanced by advances in nanotechnology.
This easy-to-understand guide in the highly respected Clark's stable of diagnostic imaging texts is an invaluable tool for student and qualified radiographers, providing practical advice and instruction on how to formulate a comment following image evaluation of musculoskeletal X-rays.
Neutrophil Methods and Protocols provides a concise set of protocols for assessing basic neutrophil functions, investigating specialized areas in neutrophil research, and completing step-by-step diagnostic assays of common neutrophil disorders.
A panel of internationally recognized research scientists and clinical investigators brings together a diverse collection of readily reproducible methods for identifying and quantifying a large number of specific genetic abnormalities associated with the broad spectrum of myeloid malignancies.
Many questions remain unresolved as researchers continue to characterize and define the nature of normal immune homeostasis and determine how these processes are dysregulated in immunodeficiency, as well as in autoimmune and lymphoproliferative disorders.
