As autism is associated with many rare diseases, this extensive bench book examines how no one single model can be used; multiple organism models are needed, each one corresponding to one of the diseases or to one aspect of a disease.
This detailed volume reflects the considerable new developments that have taken place in the area of applied neurogenomics, particularly with the rapid progress in next generation sequencing.
This detailed volume covers molecular biology, cellular biology, biomarkers, imaging, and neuropathological methods and techniques to explore multiple sclerosis (MS), with a special emphasis on disease models.
This volume presents the latest data on recent achievements in new and emerging technologies for stroke biomarkers and innovations in stroke assessment.
Modern Electroencephalographic Assessment Techniques: Theory and Applications presents numerous signal processing and connectivity analysis methodologies addressing a wide variety of clinical applications including epilepsy, schizophrenia, Alzheimer's disease and even alcoholism.
Parkinson's disease is a progressive neurodegenerative disorder charact- ized clinically by tremor, rigidity, slow movements, and postural instability.
While researchers with Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) essentially addressed questions from the whole spectrum of cardiology, oncology, and the neurosciences, it was most notably the latter that provided completely new insights into physiological and disturbed human brain function.
Neuroproteomics: Methods and Protocols presents experimental details for applying proteomics to the study of the central nervous system (CNS) and its dysfunction through trauma and disease.
The successful previous volume on this topic provided a detailed benchwork manual for the most commonly used animal models of acute neurological injuries including cerebral ischemia, hemorrhage, vasospasm, and traumatic brain and spinal cord injuries.
Continuing the research of the best-selling first edition, Patch-Clamp Analysis: Advanced Techniques, Second Edition collects three more years of research in the ever-expanding study of the cell membrane.
As fMRI technology has provided invaluable insights into the mechanisms through which the human brain works in healthy individuals and in patients with different neurological and psychiatric conditions, the study of brain function and even the monitoring of the effects of treatment have become more effective and efficient.
Despite the difficulty in comparing clinic-based human tests with animal model testing, there is still great value in pursuing translational approaches, as tests and treatment strategies might be developed to improve brain function in humans suffering from neurological conditions and knowledge obtained from human behavioral studies can be used to further improve the animal models of behavioral analysis.
The successful previous volume on this topic provided a detailed benchwork manual for the most commonly used animal models of acute neurological injuries including cerebral ischemia, hemorrhage, vasospasm, and traumatic brain and spinal cord injuries.
Although the available models, whether at the cellular, tissue, or animal level, do not exactly represent the biology of human brain tumors, animal models can offer significant insights into these tumors, providing a better understanding of biological mechanisms underlying tumor generation, growth, angiogenesis, invasion, and metastasis.
In the last decade, several different optical imaging techniques, either based on various voltage or calcium dyes, or more recently on modified fluorescent or bioluminescent proteins (genetically encoded) that are sensitive to calcium, have been developed to study neuronal activity, and especially groups of neurons, with the goal of mapping and deciphering the neural code underlying major neurophysiological functions.
Alzheimer's disease and frontotemporal dementia, two of the most prevalent neurodegenerative diseases, are dreaded disorders that attack the neural networks underlying memory and personality, systems that make us who we are.
As the presence of genetically modified animal models in research laboratories has multiplied, the role of genetic factors in the pathogenesis of brain disorders has become particularly important.
For nearly 30 years, the Concise Guide to Neuropsychiatry and Behavioral Neurology has been an indispensable companion for clinicians caring for patients struggling with everything from delusions and hallucinations to aphasia and stroke.
The detrimental impacts of pain on the quality of our daily life have drawn increasing attention from researchers, health care providers, policymakers, and social workers.
With an ever-increasing elderly population and the resultant rising levels of dementia-related disorders, preclinical research based on animal models is pivotal to our knowledge of underlying molecular mechanisms and drug discovery aiming at the development of therapeutic strategies alleviating or preventing the neurological devastation.
The application of optical methods for investigating neocortical circuit dynamics has greatly expanded in recent years, providing novel insights into the fascinating world of brain function.
Originally published in 1984, the overall purpose of this book was to provide ideas and suggestions about the usefulness of applied psychology in dealing with some of the problems of the elderly.
As a consequence of demographic change, it is increasingly necessary now and in the future for the architectural profession to rethink the design of residential solutions for aging people and especially those with dementia.
"Anticiparse con algún tipo de consideración ya sea personal, afectiva o, incluso, con pretensiones académicas a un libro escrito por otros es no solo difícil sino atrevido.
The second edition of this concise, easy-to-read title is designed for clinical teachers looking to refine their approach to teaching professional attitudes and basic skills to medical students.
This book is focused on trigeminal neuralgias and their management, a field in which, during the two past decades, there were numerous advances in comprehension of mechanisms of the disease and diagnosis with imaging, as well as in medical therapies and in surgical treatment.
Sleep disorders are very common among women during their lifespan, presenting in isolation or in combination with other illnesses particularly psychiatric and neurologic disorders.
This book provides a detailed overview of the latest developments in the rapidly evolving specialty of Neuro-Oncology arranged in approximately 500 questions arranged in multiple-choice and matching formats.
This book provides an in-depth review of the knowledge of craniospinal arachnoid cysts, with emphasis on epidemiology, genetics, neuroimaging, clinical presentations, and operative management.
This book provides an overview of planning and examining the methodology, analytic issues, primary and secondary endpoints and outcomes in headache trials.
This practical question and answer book covers topics within the field of neurocritical care, including aspects of neurology, neurosurgery, general critical care, and emergency medicine.
Die Neuroonkologie umfasst ein breites Spektrum von Erkrankungen, darunter primäre Tumore und Metastasen im Nervensystem, Tumorprädispositionssyndrome und Tumortherapie-assoziierte neurologische Symptome.
This new edition of Neurosurgery: The Essential Guide to the Oral and Clinical Neurosurgical Exam provides a concise and practical guidebook of the core knowledge and principles for the International and Intercollegiate FRCS Specialty Examination in Neurosurgery.
This new edition of Neurosurgery: The Essential Guide to the Oral and Clinical Neurosurgical Exam provides a concise and practical guidebook of the core knowledge and principles for the International and Intercollegiate FRCS Specialty Examination in Neurosurgery.
