Concerns about the adverse health effects of chemicals and radiation present in the environment and at workplaces have created the need for better detection systems to assess their potential to cause DNA damage in humans and other organisms across ecosystems.
Each day we are exposed to a myriad of natural and human-made chemicals in our food, drinking water, air, soil, at home or at the workplace-pesticide residues, food additives, drugs, household products-but how can we gauge the human health risk posed by these chemicals?
Explores the benefits and limitations of the latest high-throughput screening methods With its expert coverage of high-throughput in vitro screening methods for toxicity testing, this book makes it possible for researchers to accelerate and streamline the evaluation and risk assessment of chemicals and drugs for toxicity.
Systems Biology in Toxicology and Environmental Health uses a systems biological perspective to detail the most recent findings that link environmental exposures to human disease, providing an overview of molecular pathways that are essential for cellular survival after exposure to environmental toxicants, recent findings on gene-environment interactions influencing environmental agent-induced diseases, and the development of computational methods to predict susceptibility to environmental agents.
Toxische Stoffe sind ubiquitär und auf Grund hochempfindlicher Analysenmethoden in allen umweltrelevanten Matrices, biologischen Materialien und Lebensmitteln nachweisbar.
Biomarkers in Environmental and Human Health Biomonitoring: An Integrated Perspective provides a holistic view of the biomonitoring of environmental degradation, accumulated toxicity, and associated human health concerns.
The aim of this book is to provide the scientific background to using the formation of chemical categories, or groups, of molecules to allow for read-across i.
The Handbook of Pesticide Toxicology is a comprehensive, two-volume reference guide to the properties, effects, and regulation of pesticides that provides the latest and most complete information to researchers investigating the environmental, agricultural, veterinary, and human-health impacts of pesticide use.
This new, and heavily revised, edition of Psychopharmacology, provides a comprehensive scientific study of the effects of drugs on the mind and behavior.
Highlighting cutting-edge research on human exposure to endocrine toxicants and the related harmful effects, this book focuses on the challenges of dealing with increasing pollution levels, increased use of synthetic chemicals, and environmental endocrine disruptors that endanger the human endocrine system and its hormones.
This volume provides extensive health (toxicological) and safety handling information and data on over 1,000 chemicals of commercial and industrial importance.
Receptors and Cellular Pharmacology is a collection of the proceedings of the Sixth International Congress of Pharmacology held in Helsinki, Finland, on July 20-25, 1975 and organized by the Finnish Pharmacological Society.
This report reviews documents on acute exposure guideline levels (AEGLs) for nerve agents GA (tabun), GB (sarin), GD (soman), GD, and VX, sulfur mustard, diborane, and methyl isocyanate.
A Colour Handbook of Skin Diseases of the Dog and Cat was one of the first books to bring key information about skin diseases to clinicians in an easy-to-use problem-oriented format.
This book describes, with references to key source materials, the background to, and conduct of, the principal nonclinical studies that are central to drug development.
The standard-setting reference in medical toxicology-trusted as the leading evidencebased resource for poison emergenciesA Doody's Core Title for 2017!
Anticancer Treatments and Cardiotoxicity: Mechanisms, Diagnostic and Therapeutic Interventions presents cutting edge research on the adverse cardiac effects of both radiotherapy and chemotherapy, brought together by leaders in the field.
The first thorough review of cyclooxygenase inhibitors, including their toxicity mechanisms and toxicopathological risks Cyclooxygenases (COXs) are enzymes responsible for the formation of an important class of biological mediators called prostanoids.
Environmental Contaminants and Medicinal Plants Action on Female Reproduction discusses the problem of environmental pollution, medicinal and food plants, and their impact on reproduction.
Toxicological Evaluation of Electronic Nicotine Delivery Products (ENDP) discusses the scientific basis for the toxicological assessment and evaluation of ENDPs.
A Colour Handbook of Skin Diseases of the Dog and Cat was one of the first books to bring key information about skin diseases to clinicians in an easy-to-use problem-oriented format.
Guide to Food Safety and Quality During Transportation provides a sound foundation for the improvement of the transportation sector responsible for the movement of food.
Current Concepts in Kinin Research contains the proceedings of the Satellite Symposium of the 7th International Congress of Pharmacology held in Paris on July 22, 1978.
Environmental toxicology is generally held to be the study of the potential of constituents of outdoor environments to impact either human health or the biological structure of the ecosystems involved.
This is the first book about both normal development of the nervous system and how early exposure to alcohol and nicotine interferes with this development.
Toxicoepigenetics: Core Principles and Applications examines the core aspects of epigenetics, including chromatin biology, DNA methylation, and non-coding RNA, as well as fundamental techniques and considerations for studying each of these mechanisms of epigenetic regulation.
Este libro se escribió porque la es un tema de actualidad, para el cual no existe en el país un texto de consulta fácil, lectura ágil, con conceptos actualizados y un enfoque netamente clínico en idioma español que abarque los aspectos más importantes de esta disciplina.
Handbook of Hypertension, Volume 3: Pharmacology of Antihypertensive Drugs presents the biological and clinical knowledge in the field of hypertension.
Contamination of drinking water is a worldwide problem, and ongoing work is taking place across the globe to address the issues affecting this precious commodity.
This book discusses a wide range of health-related mining issues, with particular reference to occupational diseases, metal toxicity, postural injuries in miners, modern fire safety controls, noise-induced hearing loss prevention, and noise mapping.
Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research presents the detailed systematic anatomy of the rat, with a focus on toxicological needs.
Physiological Pharmacology: A Comprehensive Treatise, Volume III: The Nervous System - Part C: Autonomic Nervous System Drugs focuses on the effects of drugs on the nervous system, including cardiovascular effects and metabolism.
Systemic Drug Delivery Strategies: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy, Volume 2 examines the challenges of delivering immuno-oncology therapies, focusing specifically on the multiple technologies of affective drug delivery strategies.
In this important reference work, Zeliger catalogs the known effects of chemical mixtureson the human body and also proposes a framework for understanding and predicting theiractions in terms of lipophile (fat soluble) / hydrophile (water soluble) interactions.
Gain practical knowledge of the entire field of toxicology with this beautifully illustrated guideThe Illustrated Handbook of Toxicology is an impressive introduction to the complex field of toxicology.
Water containing significant amounts of inorganic and organic contaminants can have serious environmental consequences and serious health implications when ingested.
The book provides an overview of different nanoparticles, their classification, and their applications in healthcare, food sciences, environmental sciences, and agricultural sciences.