Hazardous agents are an ongoing concern in the modern workplace, with many examples of workers being severely affected by chemicals as a result of both acute and chronic exposure.
"e;Offers comprehensive coverage of the latest toxicological, technological, and nutritional developments in both natural and synthetic antioxidants used in the food industry.
The most talked about metalloid in the modern world, arsenic affects the liver, kidney, and lungs; leads to cardiovascular diseases, cancer, and diabetes; and may cause blindness with long-time exposure.
Biomaterials, Medical Devices, and Combination Products is a single-volume guide for those responsible for-or concerned with-developing and ensuring patient safety in the use and manufacture of medical devices.
Functional foods and nutraceuticals, dietary supplements, and natural antioxidants have established their potential roles in the protection of human health against disease.
Adverse Drug Interactions: A Handbook for Prescribers assists clinicians by providing key information on potential adverse effects that can result from prescribing two or more drugs for simultaneous use.
Accurate uranium analysis, and particularly for isotope measurements, is essential in many fields, including environmental studies, geology, hydrogeology, the nuclear industry, health physics, and homeland security.
In Infertile Environments, Janelle Lamoreaux investigates how epigenetic research into the effects of toxic exposure conceptualizes and configures environments.
Designed for graduate and advanced undergraduate courses, this book goes beyond the simple analysis of naming a drug or toxin, taking a mechanistic approach to their effects on the body.
The last few years have brought about many changes in the field of marine and freshwater toxins, with advances in analytical technology and the realization that these toxins are a global issue.
Today, we are exposed to an increasing number of chemicals in the environment and there is a growing awareness of the effects of these chemicals on the ovaries.
Neurotransmitters are usually considered to be endogenous substances that are released from neurons, act on receptor sites that are typically present on membranes of postsynaptic cells and produce a functional change in the properties of the target cell.
This 2nd Edition is a significantly expanded exploration of hazardous chemicals, their effects on human health, and the principles of hazards materials toxicology and industrial hygiene.
High-precision cleaning is required across a wide range of sectors, including aerospace, defense, medical device manufacturing, pharmaceutical processing, semiconductor/electronics, etc.
Carbon-Based Nanocarriers for Drug Delivery enlists the latitudes and advancements in the synthesis processes, functionalization, and applications of carbon-based nanomaterials (CBNs) in targeted drug delivery systems (DDSs).
A great deal of confusion and uncertainty over genotoxic impurity (GTI) identification, assessment, and control exists in the pharmaceutical industry today.
Building from the perspective of reproductive and developmental biology, Computational Methods for Reproductive and Developmental Toxicology provides a timely and comprehensive overview of approaches in reproductive and developmental toxicology.
In the last decade and a half, great progress has been made in the development of concepts and models for mixture toxicity, both in human and environmental toxicology.
A comprehensive resource, this volume offers a tool for the management of a range of chemical substances commonly used, handled, stored, transported, and disposed of as wastes.
Capturing the growth of the global medical device market in recent years, this practical new guide is essential for all who are responsible for ensuring safety in the use and manufacture of medical devices.
Reversibility of Chronic Disease and Hypersensitivity, Volume 4: The Environmental Aspects of Chemical Sensitivity is the fourth of an encyclopedic five-volume set describing the basic physiology, chemical sensitivity, diagnosis, and treatment of chronic degenerative disease studied in a 5x less polluted controlled environment.
Many of the toxic effects elicited by xenobiotics can be explained at the molecular level by their interaction with receptors or by disruption or interference with receptor-mediated signal transduction pathways.
The use of drugs as remedies for various types of diseases has a long tradition; however, it has only been recently recognized that the value of any given compound must be evaluated in light of its benefit to risk ratio.
Molecular toxicology is an emerging discipline that utilizes molecular and cell biology to understand how drugs and chemicals result in their unwanted effects.
Since the publication of the original edition in 1982, pesticide-related poisonings, both single cases and epidemic-scale situations, have continued to occur unabated.
Neurotoxicology provides a thorough understanding of neurotoxicology through its integration of multilateral ideas covering several disciplines, including chemistry, biochemistry, anatomy, physiology, and pathology.
This up-to-date reference includes the most recent available data and detailed case studies concerning the potential health risks of aflatoxin in the human population.
In this important reference work, Zeliger catalogs the known effects of chemical mixtureson the human body and also proposes a framework for understanding and predicting theiractions in terms of lipophile (fat soluble) / hydrophile (water soluble) interactions.
Karch's Drug Abuse Handbook, Third Edition remains the quintessential compendium addressing the pharmacological, medical, and legal aspects of drugs and informing the forensic community of the latest scientific advances and emergent practices.
As a result of new statistical and mathematical approaches, improved visualization tools, and recognition by international regulatory groups, quantitative structure-activity relationships (QSARs) now play important roles in pharmacology for the design of new drugs as well as in toxicology and ecotoxicology for hazard identification and risk assessm
The application of molecular biologic methods, recognition of neurogenic inflammatory processes, and utilization of genetic knockout animals are just some of the advances in toxicology of the upper airways in recent years.
Occupational workers frequently use, store, and dispose of toxic chemicals without knowing the possible consequences, both for the workplace and the environment.
Hematology data from in vivo toxicology studies remains one of the most predictive measures for human risk, as the same measurements made in pre-clinical toxicology studies can be made in early clinical trials.
This key volume of the Target Organ Toxicology Series provides a fresh and modern approach to the subject of skin toxicology from the perspective of how the skin forms a barrier that protects the body from the external environment and how chemicals and drugs interact with the barrier properties of the skin.
This new edition presents an integrated approach to neurotoxicology, the study of organisms' responses to changes in their environment and how interruption of the flow of information by chemical exposure causes a wide range of effects - from learning deficits, sensory disturbances in the extremities, and muscle weakness to seizures and signs similar to neurodegenerative disorders such as Parkinson's or Alzheimer's disease.
Forensic Issues in Alcohol Testing analyzes the acute and chronic effects of alcohol intoxication and a variety of methods with which to measure alcohol concentration in blood, urine, and breath testing.
Encouraged by the medicinal success of quinine, early 19th century scientists hoped strychnine, another plant alkaloid with remarkable properties, might also become a new weapon against disease.
Highlighting latest advances in genetics and biochemistry, the completely revised Third Edition reviews the field from basic science, clinical, epidemiological, and regulatory perspectives.
Beginning with a definition and explanation of scheduling of controlled substances, Pathology, Toxicogenetics, and Criminalistics of Drug Abuse covers investigative methods for all illegal drugs and several legitimate pharmaceuticals that are used illicitly, including steroids.
