The analytical toxicologist may be required to detect, identify, and in many cases measure a wide variety of compounds in samples from almost any part of the body or in related materials such as residues in syringes or in soil.
Prominent contributors address issues regarding the toxicity of aluminum which causes an encephalopathy in renal dialysis patients and is also known to damage animals and plants via acid rain.
Cocaine poses interesting problems for neurophysiologists and neuropharmacologists and there is important new data on the effects of cocaine on the brain (its initial site of action at the cellular level now appearing to be the dopamine transporter).
Nicotine is considered to be the main agent in the maintenance of the tobacco smoking habit and is largely responsible for the behavioral and physiological responses to the inhalation of tobacco smoke.
Process-Induced Food Toxicants combines the analytical, health, and risk management issues relating to all of the currently known processing-induced toxins that may be present in common foods.
An important reference which provides an overview of the current and recently introduced methodologies for testing the immunotoxic risks in drug candidates Helps readers understand the significance of the methods and approaches to immunotoxicology testing Aids drug scientists in industry and regulatory areas to consolidate approaches to immunotox testing Offers a definitive assessment of nonclinical models to study the toxic impacts (bio)pharmaceuticals can have on the immune system Includes chapter authors from across the pharma industry, bringing a real-world and applied perspective to immunotox testing
This is the definitive, one-stop resource on preclinical drug evaluation for potential mitochondrial toxicity, addressing the issue upfront in the drug development process.
A comprehensive analysis of state-of-the-art molecular modeling approaches and strategies applied to risk assessment for pharmaceutical and environmental chemicals This unique volume describes how the interaction of molecules with toxicologically relevant targets can be predicted using computer-based tools utilizing X-ray crystal structures or homology, receptor, pharmacophore, and quantitative structure activity relationship (QSAR) models of human proteins.
This book aims to fill the gap that exists between theoretical treatments of chromatography, and clinical chemistry and toxicology texts, which focus almost exclusively on clinical relevance and applications.
Occupational Neurology a volume in the Handbook of Clinical Neurology Series, provides a comprehensive overview of the science, clinical diagnosis, and treatment for neurotoxin related neurological and psychiatric disorders.
The compilation of this book was prompted by the necessity of a bench volume which could provide the necessary background information on materials, experimental design, pitfalls and dificulties, in order to perform a particular test in an acceptable way with a minimal need for additional expert help.
Building upon the success of previous editions of the bestselling Handbook of Laboratory Animal Science, first published in 1994, this latest revision combines all three volumes in one definitive guide.
Building upon the success of previous editions of the bestselling Handbook of Laboratory Animal Science, first published in 1994, this latest revision combines all three volumes in one definitive guide.
This book examines social processes that have contributed to growing pesticide use, with a particular focus on the role governments play in urban aerial pesticide spraying operations.
This book examines social processes that have contributed to growing pesticide use, with a particular focus on the role governments play in urban aerial pesticide spraying operations.
This book provides an overview of Asphyxial Deaths which includes hanging, strangulation, choking, smothering, gagging, drowning, aspiration, mechanical and chemical asphyxiants, etc.
This book provides an overview of Asphyxial Deaths which includes hanging, strangulation, choking, smothering, gagging, drowning, aspiration, mechanical and chemical asphyxiants, etc.
The concept of the 3Rs (Refinement, Reduction and Replacement) has been used as a framework for improving the welfare of laboratory animals for the last half century.
The concept of the 3Rs (Refinement, Reduction and Replacement) has been used as a framework for improving the welfare of laboratory animals for the last half century.
Updating and expanding the scope of topics covered in the previous edition, Percutaneous Absorption: Drugs, Cosmetics, Mechanisms, Methods, Fifth Edition supplies new chapters on topics currently impacting the field including cutaneous metabolism, skin contamination, exposure to protein allergens, in vitro absorption methodology and the percutaneous absorption of chemical mixtures.
Updating and expanding the scope of topics covered in the previous edition, Percutaneous Absorption: Drugs, Cosmetics, Mechanisms, Methods, Fifth Edition supplies new chapters on topics currently impacting the field including cutaneous metabolism, skin contamination, exposure to protein allergens, in vitro absorption methodology and the percutaneous absorption of chemical mixtures.
Oxidative Stress: Its Impact on Human Health and Disease Onset examines all factors known to elevate oxidative stress (OS) and the mechanism of OS disease causation.
Hazardous Gases: Risk Assessment on Environment and Human Health examines all relevant routes of exposure, inhalation, skin absorption and ingestion, and control measures of specifics hazardous gases resulting from workplace exposure from industrial processes, traffic fumes, and the degradation of waste materials and how they impacts the health and environment of workers.
Environmental Contaminants and Medicinal Plants Action on Female Reproduction discusses the problem of environmental pollution, medicinal and food plants, and their impact on reproduction.
Toxicological Risk Assessment and Multisystem Health Impacts From Exposure highlights the emerging problems of human and environmental health attributable to cumulative and multiple sources of long-term exposure to environmental toxicants.
Emerging Nanotechnologies in Immunology aims to deliver a systematic and comprehensive review of data concerning the nature of interaction and nano-related risks between the nanophamaceuticals currently in the pipeline of S&T development for skin, ocular, and nasal drug delivery, including absorption, toxicity, and the ability to distribute after systemic exposure.
Marijuana and Health Hazards: Methodological Issues in Current Research is a collection of manuscripts presented at a conference on methodological issues involving marijuana research, held in Washington, D.
Toxic Constituents of Animal Foodstuffs focuses on toxic substances that occur naturally as well as those that are deliberately or inadvertently introduced by man in animal foodstuffs.
Pyrethrum: the Natural Insecticide covers the papers presented at the 1972 "e;"e;International Symposium on Recent Advances with Pyrethrum the Natural Insecticide"e;"e; held in conjunction with the American Institute of Biological Sciences Silver Anniversary Meeting at the University of Minnesota, Minneapolis.
Fungicides, Volume I: Agricultural and Industrial Applications, Environmental Interactions discusses the application, use, and environmental interactions of fungicides.
Handbook of Hazardous Materials is a one-volume compendium of hazardous materials that discusses the toxic effects of these materials on human health and the global environment.
A new companion study guide to the most respected text in pharmacy educationGoodman & Gilman s Workbook for Pharmacologic Therapeutics delivers concise, high-yield summaries of the world-renowned coverage of the actions and uses of therapeutic agents in relation to physiology and pathophysiology found in Goodman & Gilman s The Pharmacological Basis of Therapeutics.
