It is now well recognized that the brain, and especially the hypothalamus, plays an important role in the regulation of immune reactions and inflammation.
This book brings together key features of the toxicology and occupational hazards of pesticides and the way their use is regulated in the main trading regions of the world.
Chelation Therapy in the Treatment of Metal Intoxication presents a practical guide to the use of chelation therapy, from its basic chemistry, to available chelating antidotes, and the application of chelating agents.
Handbook of Arsenic Toxicology, Second Edition presents the latest findings on arsenic, including its chemistry, sources and effects on the environment and human health.
Absorption, Distribution, Metabolism and Excretion (ADME) processes and their relationship with the design of dosage forms and the success of pharmacotherapy form the basis of this upper level undergraduate/graduate textbook.
Nonclinical Development of Novel Biologics, Biosimilars, Vaccines and Specialty Biologics is a complete reference devoted to the nonclinical safety assessment of novel biopharmaceuticals, biosimilars, vaccines, cell and gene therapies and blood products.
Anticancer Treatments and Cardiotoxicity: Mechanisms, Diagnostic and Therapeutic Interventions presents cutting edge research on the adverse cardiac effects of both radiotherapy and chemotherapy, brought together by leaders in the field.
**Selected for Doody's Core Titles(R) 2024 in Endocrinology/Metabolic Disease**Updated with new and expanded chapters, Endocrine Disruption and Human Health, Second Edition provides an introduction to what endocrine disruptors are, the issues surrounding them, the source of these chemicals in the ecosystem and the mechanisms of action and assay systems.
This handbook is a reference source for identifying, characterizing, instructing on use, and describing outcomes of neurotoxin treatments - to understand mechanisms associated with toxin use; to project outcomes of neurotoxin treatments; to gauge neurotoxins as predictors of events leading to neurodegenerative disorders and as aids to rational use of neurotoxins to model disease entities.
Biocompatibility Protocols for Medical Devices and Materials provides comprehensive coverage of the basic science and toxicological testing protocols necessary for the risk assessment and safety analysis of medical devices and materials which are based on the ISO guidelines for body contact and duration of contact.
An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from "e;simple molecular systems, to complex human communities, with expertise from a spectrum of interacting disciplines.
Exposure and Risk Assessment of Pesticide Use in Agriculture: Approaches, Tools and Advances offers an overview of the different methods available in toxicology for pesticide exposure and risk assessment, ranging from the regulatory field, to in-field research studies.
The Prostaglandins: Pharmacological and Therapeutic Advances provides a concise account of the more important theoretical developments and areas in which the prostaglandins are being introduced into clinical practice or have potential clinical application.
Mutagenicity: Assays and Applications presents an extensive examination of the detection, assessment and future of mutagenicity, particularly as it concerns human health and the environment.
**Selected for Doody's Core Titles(R) 2024 in Toxicology**The second edition of Forensic Toxicology: Principles and Concepts takes the reader back to the origins of forensic toxicology providing an overview of the largely unchanging principles of the discipline.
The most trusted all-in-one overview of the biomedical and environmental aspects of toxicology--NOW more complete, up-to-date, and in full colorThe world's leading and most authoritative textbook on poisons has more to offer students,toxicologists, and pharmacologists than ever before.
Despite ongoing efforts to prohibit the production, storage and use of chemical warfare agents recent world events highlight the enduring threat to the population from these agents.
The History of Alternative Test Methods in Toxicology uses a chronological approach to demonstrate how the use of alternative methods has evolved from their conception as adjuncts to traditional animal toxicity tests to replacements for them.
As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process.
A very handy practical book written by French doctors specialised in disaster medicine, this guide offers their core experience condensed in 50 small, easily digestible chapters.
Marijuana and Health Hazards: Methodological Issues in Current Research is a collection of manuscripts presented at a conference on methodological issues involving marijuana research, held in Washington, D.
Updating and expanding the scope of topics covered in the previous edition, Percutaneous Absorption: Drugs, Cosmetics, Mechanisms, Methods, Fifth Edition supplies new chapters on topics currently impacting the field including cutaneous metabolism, skin contamination, exposure to protein allergens, in vitro absorption methodology and the percutaneous absorption of chemical mixtures.
An important reference which provides an overview of the current and recently introduced methodologies for testing the immunotoxic risks in drug candidates Helps readers understand the significance of the methods and approaches to immunotoxicology testing Aids drug scientists in industry and regulatory areas to consolidate approaches to immunotox testing Offers a definitive assessment of nonclinical models to study the toxic impacts (bio)pharmaceuticals can have on the immune system Includes chapter authors from across the pharma industry, bringing a real-world and applied perspective to immunotox testing
Microbial Toxins: A Comprehensive Treatise, Volume VIII, Fungal Toxins is devoted to topics related to algal and fungal toxins and includes critically reviewed articles from different experts in related fields.
Biochemical and Pharmacological Roles of Adenosylmethionine and the Central Nervous System contains the proceedings of an International Round Table on Adenosylmethionine and the Central Nervous System held in Naples, Italy, on May 2, 1978.
This book provides an overview of Asphyxial Deaths which includes hanging, strangulation, choking, smothering, gagging, drowning, aspiration, mechanical and chemical asphyxiants, etc.
Veterinary Toxicology for Australia and New Zealand is a reference suited to the unique challenges of veterinary practice in Australia and New Zealand.
This book explores the different uses of inulin in pharmaceutical formulations, its potential therapeutic benefits, and the regulatory considerations involved in developing inulin-based pharmaceutical products.
Molecular Biological Markers for Toxicology and Risk Assessment provides an introduction to the exciting field of biomarkers and their use in toxicology and risk assessment.
This is the definitive, one-stop resource on preclinical drug evaluation for potential mitochondrial toxicity, addressing the issue upfront in the drug development process.
Anabolic Steroids attempts to trace the development of anabolic steroids in the chemical, experimental biological, and clinical disciplines, and presents a precise outline of the current state of substantiated knowledge.
Proceedings of the Second International Pharmacological Meeting, Volume 1: Pharmacology of Conditioning, Learning and Retention is a collection of papers presented at the Second International Pharmacological Meeting on August 20-23, 1963.
Drug Design, Volume VII covers the design of agents such as blood substitutes, pesticides derived from insect pheromones, and herbicides related to the auxin-type plant hormones.