Very few therapeutic agents in clinical medicine have found indication for so many clinical conditions, and in such a short time as did botulinum neurotoxins (Botox and others).
This book on current approaches to the use of drugs in dentistry aims to equip practitioners with a sound understanding of both the scientific evidence for various interventions and the comparative efficacy of those interventions.
This volume addresses one of the Holy Grails in Psychiatry, namely the evidence for and potential to adopt 'Biomarkers' for prevention, diagnosis, and treatment responses in mental health conditions.
This textbook provides a structured, easy to understand and thorough insight into the mode of function of plant secondary metabolites in plants and humans.
This volume gives an overview of new insights to alcohol pharmacology using DREADDs (Designer Receptors and Unraveling the Neuropharmacology of Alcohol).
This work brings together a wealth of data regarding the reference values and factors of variation in biochemical parameters used by camel veterinarians and scientists to determine these animals' nutritional and clinical status.
This book summarizes the fast-growing and current knowledge about selenium interaction with cancer, diabetes, neuro-degeneration, heart disease, muscle disorders, HIV and several more.
Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology.
This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states.
This book presents an extensive study on the effectiveness of recent regulations on pharmaceutical prices in India, exploring the weaknesses in the design and implementation of pharmaceutical price controls and investigating what can be done to fix the broken system.
This book starts with a general introduction to phytochemistry, followed by chapters on plant constituents, their origins and chemistry, but also discussing animal-, microorganism- and mineral-based drugs.
This Brief takes the reader on a chemical journey by following the history for over two centuries of how an opiate became an opioid, thus spawning an empire and a series of crises.
This first monograph in the new AAPS book series concisely reviews important aspects of powder and particle systems and the critical quality attributes that should be used as a guide to future developments intended to maximize the control of product quality and performance.
This volume contains reviews and brief research articles from participants attending the International Society for Arterial Chemoreception meeting, to be held in the USA (July 2017).
This book is an unbiased scientific compendium documenting the state-of-the-art in the etiology, diagnosis and treatment of Cannabis Use Disorders (CUD).
This book provides a timely state-of-the-art overview of voltage-gated sodium channels, their structure-function, their pharmacology and related diseases.
This book presents a systematic overview of the most relevant nanomaterials and their respective intrinsic properties that have been highly explored by the scientific community and pharmaceutical companies in several different modalities for cancer therapy and bioimaging.
This book provides an in-depth explanation of the advantages and current limitations of recombinant plant-made vaccines for use in veterinary medicine, including for livestock, pets, and wild animals.
Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology.
Over the last decade, and particularly during the recent five years, a rapidly increasing number of novel psychoactive substance (NPSs), often marketed as "e;designer drugs"e;, "e;legal highs"e;, "e;herbal highs"e;, "e;research or intermediate chemicals"e; and "e;laboratory reagents"e;, has appeared on the drug market in an effort to bypass controlled substance legislation.
The application of bioinformatics approaches in drug design involves an interdisciplinary array of sophisticated techniques and software tools to elucidate hidden or complex biological data.
This book addresses the highly relevant subject of emerging pollutants, which are especially alarming since most of the available treatment technologies are unable to degrade them.
Focused more specifically on the recent advances in applications of various metals and their complexes used in biomedicine, particularly in the diagnosis and treatment of chronic diseases.
Drug resistance is a fundamental factor in treatment failure in diseases like leishmaniasis, although additional factors also play a role in this phenomenon.
This book addresses the therapeutic strategies to target mitochondrial metabolism in diseases where the function of that organelle is compromised, and it discusses the effective strategies used to create mitochondrial-targeted agents that can become commercially available drug delivery platforms.
This is the second edition of a well-received book that reflects the state of the art in cancer medical therapies and their side-effects, including immunotherapy and chemotherapeutic drugs.
This is the second edition of a well-received book in the series "e;Drug Discovery and Evaluation"e; The completely revised new edition of the volume reflects the current state of the art in Clinical Pharmacology.
This book investigates and highlights the most critical challenges the pharmaceutical industry faces in an increasingly competitive environment of inflationary R&D investments and tightening cost control pressures.
Social pressure to minimize the use of animal testing, the ever-increasing concern on animal welfare, and the need for more human-relevant and more predictive toxicity tests are some of the drivers for new approaches to chemical screening.
This graduate textbook imparts the fundamentals of reliability and risk that can be connected mathematically and applied to problems in engineering and medical science and practice.