Pharmacology

Most studies on autonomic innervation of smooth muscle have focused on the short-term mechanisms involved in neurotransmission in physiological and pathophysiological conditions.

Infection of the lower respiratory tract is a major determinant of the course of cystic fibrosis.

The 39 chapters in this volume consider subjects ranging from genetics, markers, and molecular biology of alcoholism, to clinical observations and treatment.

Volume 42 of "e;Progress in Drug Research"e; contains seven reviews and the various indexes which facilitate its use and establish the con- nection with the previous volumes.

Volume 43 of Progress in Drug Research contains five reviews and the various indexes which facilitate its use and establish the connection with the previous volumes.

This volume arose from the scientific program of the XIIth International Congress of Pharmacology, held in Montreal, Canada, July 24-29, 1994.

The Second IUPHAR Satellite Meeting on Serotonin was held under the auspices of the Serotonin Club in Basel, Switzerland in July 1990.

With the present Badgastein Symposium "e;Radioactive Isotopes in Clinical Medicine and Research"e; we have now had 40 years of an uninterrupted series of Badgastein meetings on nuclear medicine, since the first one took place in January 1954.

This book provides a useful text for research students and scientists on the latest knowledge about the immune system of fish, cutting edge technologies and the step required to develop, test and commercialise fish vaccines.

This volume describes the pathogenesis and pathophysiology of several pulmonary diseases as well as their treatment.

In recent years there have been a number of significant developments of natural products for the treatment of rheumatic diseases, pain and gastro-intestinal ulcers and inflammation.

This volume provides an up-to-date account of the achievements pertaining to the application of capsaicin and capsaicin-like molecules in the therapy of various human ailments such as pain, non-allergic rhinitis, obesity, tumors and gastrointestinal, dermatologic and urologic disorders.

Tamoxifen is a pioneering medicine for the treatment and prevention of breast cancer.

Ibuprofen is one of the most successful drugs used worldwide for the treatment of mild to moderate pain and various inflammatory conditions.

Granulocyte colony-stimulating factor (G-CSF or GCSF) is a secreted glycoprotein that stimulates the proliferation and differentiation of granulocyte precursor cells, and induces mobilization of peripheral blood progenitor cells from the bone marrow.

Highlighting 15 selected chiral structures, which represent candidate or marketed drugs, and their chemical syntheses, the authors acquaint the reader with the fascinating achievements of synthetic and medicinal chemistry.

Chronic obstructive pulmonary disease (COPD) is a multi-component condition that results in increasingly limited airflow, usually associated with an abnormal inflammatory response of the lung.

This book provides a detailed overview of B-cell directed therapies in patients with rheumatic and systemic autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, Sjogren syndrome, ANCA-associated vasculitis and cryoglobulinemia.

Malaria has defeated previous efforts at eradication and remains a massive global public health problem despite being readily preventable and treatable.

Technological advances, together with a better understanding of the molecular biology of infectious microorganisms, are creating exciting possibilities for a new generation of replicating vaccines.

Both metabotropic and ionotropic glutamate receptors present attractive "e;druggable"e; targets in treating disorders of the central nervous system.

Endothelial dysfunction is broadly defined as a disruption of the balance between vasoactive mediators and a propensity towards an inflammatory state.

In this monograph about gene therapy of autoimmune and inflammatory d- orders we have gathered international experts and leaders from different fields to review the state of the art advances on topics ranging from disease entities to vectors and engineered cells.

This textbook provides a unique support in gaining essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals.

Growth factor receptors have long been known to drive malignant transformation and cancer progression.

This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application.

Volume Two advances the exploration of the fundamental principles of oxidative stress and toxicity on male (and female) reproduction.

New Discoveries in the Behavioral Neuroscience of Attention Deficit Hyperactivity Disorder reviews the latest developments in preclinical and clinical research of Attention Deficit Hyperactivity Disorder.

Opioids are responsible for the vast majority of preventable deaths related to drug use, and opioid crisis is a serious international health problem.

This book aims to address the infusion sequence of the main protocols used in the treatment of varied solid cancers.

This book, now in a revised and updated second edition, reviews the imaging-relevant features of selected classes of pharmaceuticals and drugs regarding CNS and head and neck images.

This book collects information about the most popular ethnomedicinal plants, which are common in Turkey and around the world.

This book covers the tremendous progress in the current understanding of the molecular physiology of voltage-gated calcium channels.

This new book provides comprehensive coverage of the subjects of deuterium oxide and deuteration in biosciences, with an emphasis on the biochemical, biomedical, and pharmacological aspects.

This textbook builds on the success of the earlier edition, offering alternative strategies for discovering new antibiotics.

The current book is focussed on the Toll-like receptors (TLRs), which are the first pattern recognition receptors (PRRs) discovered in humans.

The Pharmacology of Taste is comprised of contributions by leading scientists from the field of chemosensory research, presented all together in the context of pharmacological principles of receptor function.

This remarkable new book is the first text dedicated to the topic of pharmacovigilance for herbal and traditional medicines.

There is a growing interest in unmet needs for the development of a new discipline in drug discovery and in university education on polypharmacology.

This book offers a wide-ranging description and analysis of recent developments and current trends in health policy with regard to cancer drug safety.

This book offers a comprehensive overview of the development and application of microfluidics and biosensors in cancer research, in particular, their applications in cancer modeling and theranostics.

This third and final volume in the "e;Ion Transport in Tumor Biology"e; collection presents novel diagnostic and therapeutic approaches in cancer based on the exploitation of ion transport proteins.

The goal of this book is to provide a guide and detailed review of immunosuppression in terms of molecular mechanisms of action, side effects and clinical trials that validated their utility.

This book explains how peptide-based drug design works, what steps are needed to develop a peptide-based therapeutic, and challenges in synthesis as well as regulatory issues.

A very handy practical book written by French doctors specialised in disaster medicine, this guide offers their core experience condensed in 50 small, easily digestible chapters.

This book describes different aspects of characterization and detection of nanomaterials in liquid disperse systems, such as suspensions, emulsions and suspoemulsions.

Obesity is a major risk factor for the development of type 2 diabetes and its associated complications, a major socio-economic burden for health care systems.