The issue of male germ line mutagenesis and the effects on developmental defects in the next generation has become increasingly high profile over recent years.
Hair in Toxicology: An Important Biomonitor is the first book of its kind devoted exclusively to in-depth analysis of the hair shaft as an important tool for a diverse range of scientific investigations.
Experimental Toxicology is an important text for undergraduates, post-graduates and professionals involved with studying or teaching this often controversial subject.
This volume covers the developments in pesticide usage, with particular emphasis on the regulations that safeguard users, consumers and the environment.
Toxic fire effluents are responsible for the majority of fire deaths, and an increasing large majority of fire injuries, driven by the widespread and increasing use of synthetic polymers.
Drug delivery systems represent a vast area of research and development within biomaterials and medicine and the demand for sophisticated drug delivery devices continues to drive novel product development.
Nationally, toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to a more comprehensive study of toxicology and toxicology testing as independent entities.
The foundational reference in dermal toxicology, this classic text has been completely revised to bring it up to date in the new Eighth Edition, with almost a third of its chapters being newly added.
Formulation is a key step in the drug design process, where the active drug is combined with other substances that maximise the therapeutic potential, safety, and stability of the final medicinal product.
Implantable technologies allow for a sustained control over the release of pharmaceuticals into the bloodstream thereby achieving a controlled concentration with the potential to minimise side-effects while increasing patient compliance.
Implantable technologies allow for a sustained control over the release of pharmaceuticals into the bloodstream thereby achieving a controlled concentration with the potential to minimise side-effects while increasing patient compliance.
Drug repurposing is the development of existing drugs for new uses: given that 9 in 10 drugs that enter drug development are never marketed and therefore represent wasted effort, it is an attractive as well as inherently more efficient process.
Drug repurposing is the development of existing drugs for new uses: given that 9 in 10 drugs that enter drug development are never marketed and therefore represent wasted effort, it is an attractive as well as inherently more efficient process.
Alzheimer's disease is an increasingly common form of dementia and despite rising interest in discovery of novel treatments and investigation into aetiology, there are no currently approved treatments that directly tackle the causes of the condition.
Alzheimer's disease is an increasingly common form of dementia and despite rising interest in discovery of novel treatments and investigation into aetiology, there are no currently approved treatments that directly tackle the causes of the condition.
This publication is based on peer-reviewed manuscripts from the 2019 Conference on Drug Design & Discovery Technologies (CDDT) held at Ramaiah University of Applied Sciences, India.
Targeting protein degradation using small molecules is one of the most exciting small-molecule therapeutic strategies in decades and a rapidly growing area of research.
Targeting protein degradation using small molecules is one of the most exciting small-molecule therapeutic strategies in decades and a rapidly growing area of research.
Fibrosis is a condition with globally high unmet medical need, and as such is a highly active area of academic and pharmaceutical research covering multiple treatment targets, organs, tissues and therapeutic approaches.
The Medicinal Chemist's Guide to Solving ADMET Challenges summarizes a series of design strategies and tactics that have been successfully employed across pharmaceutical and academic laboratories to solve common ADMET issues.
The covalent conjugation of potent cytotoxic agents to monoclonal antibodies, known as antibody-drug conjugates (ADCs) is a powerful approach in the field of targeted treatment of cancer.
The covalent conjugation of potent cytotoxic agents to monoclonal antibodies, known as antibody-drug conjugates (ADCs) is a powerful approach in the field of targeted treatment of cancer.
As with the previous editions, Introduction to Toxicology, Fourth Edition, continues to chart the evolution of the field of toxicology, from the use of natural toxins by ancient tribes through the developments established by Paracelsus, and progresses through to the current topics in the public interest.
As with the previous editions, Introduction to Toxicology, Fourth Edition, continues to chart the evolution of the field of toxicology, from the use of natural toxins by ancient tribes through the developments established by Paracelsus, and progresses through to the current topics in the public interest.
Advances in Probiotic Delivery Systems: Strategies for Enhanced Viability, Targeted Delivery and Efficacy covers the complex world of probiotics, offering a comprehensive exploration of innovative delivery mechanisms designed to overcome challenges of stability and efficacy.
Peptide therapy has become a key strategy in innovative drug development, however, one of the potential barriers for the development of novel peptide drugs in the clinic is their deficiencies in clearly defined chemistry, manufacturing and controls (CMC) strategy from clinical development to commercialization.
Concerns about the adverse health effects of chemicals and radiation present in the environment and at workplaces have created the need for better detection systems to assess their potential to cause DNA damage in humans and other organisms across ecosystems.
New designer drugs, access to databases, and changing availability of samples for analysis have changed the face of modern forensic toxicology in recent years.
From pathology to treatment, MicroRNAs in Diseases and Disorders highlights the role of microRNAs (miRNAs) in the development and progression of a variety of diseases, including cancer, neurological disease, endocrine disease and autoimmune disease, and underscores the utilization of miRNA targets in the treatment of these conditions.
Metal-based anticancer drugs are among the most successful therapeutic agents, as evidenced by the frequent prescription of selected platinum and arsenic compounds to patients.
Metal-based anticancer drugs are among the most successful therapeutic agents, as evidenced by the frequent prescription of selected platinum and arsenic compounds to patients.
