Volumes in the Proven Synthetic Methods Series address the concerns many chemists have regarding irreproducibility of synthetic protocols, lack of identification and characterization data for new compounds, and inflated yields reported in chemical communications-trends that have recently become a serious problem.
This important new book provides innovative material, including peer-reviewed chapters and survey articles on new applied research and development, in the scientifically important field of QSAR in medicinal chemistry.
With extensive detailed spectral data, it contains a variety of problems designed by renowned authors to develop proficiency in organic structure determination.
Antimicrobials: Synthetic and Natural Compounds summarizes the latest research regarding the possibilities of the most important natural antimicrobial compounds derived from various plant sources containing a wide variety of secondary metabolites.
First isolated as a chemical compound by a Russian chemist in 1866, dimethyl sulfoxide (DMSO) proved to be a near-perfect solvent for decades before its remarkable biological and medical activities were discovered.
Nanomedicines and Nanoproducts: Applications, Disposition, and Toxicology in the Human Body provides a detailed overview of the disposition of nanoproducts within the body, with a special focus on the respiratory and olfactory routes of nanoproduct administration, buccal exposure and the ingestion of nanoproducts, the integumentary system (formed by the skin, hair, nails, and associated glands), the ocular route, the systemic route, and toxicology as it relates to the nanoscale world.
Practical Toxicology: Evaluation, Prediction, and Risk, Third Edition shows how to conduct a program of safety evaluation and testing and then to interpret and apply the resulting data and information in the real world, beginning with the basic concepts in toxicology and progressing to the interpretation of the resulting data.
Practical Toxicology: Evaluation, Prediction, and Risk, Third Edition shows how to conduct a program of safety evaluation and testing and then to interpret and apply the resulting data and information in the real world, beginning with the basic concepts in toxicology and progressing to the interpretation of the resulting data.
This volume provides a single-source of reviews for all the important colloidal drug delivery systems, including nanoparticles, liposomes, niosomes, microemulsions and ointments.
Handbook of Medicinal Plants of the World for Aging: Botany, Ethnopharmacology, Natural Products, and Molecular Pathways provides an unprecedented comprehensive overview of more than 100 plants used globally as medicine with the potential to prevent premature aging.
This book highlights the potential applications of microbots for minimally invasive diagnosis of colorectal cancer (CRC), enhancing the accuracy of colonoscopy and improving drug delivery for more precise and effective treatments.
This extensive volume began as a short course primarily geared toward toxicologists who want to expand their understanding of toxicologic pathology in order to be better study directors while also proving to be of great interest to other drug development scientists and regulatory reviewers.
This fully revised edition explores the management of neurological disorders with a focus on neuroprotection, disease modification, and neuroregeneration rather than symptomatic treatment.
This third edition of the Handbook of Poisonous and Injurious Plants is designed to assist the clinician in the initial response to the needs of a child or adult exposed to a poisonous or injurious plant.
The serendipitously discovered link between developmental biology and cancer, touched of an explosion of discoveries on the role of Notch in human malignancies, including every aspect of cancer biology, from control of differentiation, proliferation and apoptosis in transformed cells to angiogenesis, tumor-stroma interaction and anti-cancer immune responses.
This is the ideal book for anyone contemplating starting a career in, or shifting their career to, studying the dynamics that drive cancer progression and its response to therapy.
This book on NeuroAIDS, a collection of chapters written by experts and specialists from around the world, provides a global perspective on HIV and NeuroAIDS in the field, clinic, and laboratory.
Advances in the technology used in personalized medicine and increased applications for clinical use have created a need for this expansion and revision of Kewal K.
This book provides an authoritative overview of botulinum neurotoxin (BoNT) treatment menus for 14 pain categories with an evidence based literature review on each pain disorder, illustrative figures along with brief video clips showing the techniques and patient interviews.
This book provides trajectories and illustrations of viruses that have catapulted into the global arena (linked to humans, animals, and vectors) due to human behaviors in recent years, as well as viruses that have already shown expansion among humans, animals, and vectors just a few decades ago.
This book provides a detailed account of the most recent developments, challenges and solutions to seamlessly advance and launch a lyophilized biologics or vaccine product, based on diverse modalities, ranging from antibodies (e.
This authoritative volume examines immunohistochemical methods aimed at investigating the toxicologic pathology of rodent, non-human primate and aquatic animal tissues.
This comprehensive volume compiles the concepts essential for the understanding of the pharmaceutical science and technology associated with the delivery of subunit vaccines.
This authoritative volume explores advances in the techniques used to measure percutaneous penetration of drugs and chemicals to assess bioavailability and bioequivalence and discusses how they have been used in clinical and scientific investigations.
Current pharmaceutical and clinical approaches to the treatment of disease suffer from the inherent limitations in the specialization of drugs introduced to physiological systems.
This Brief describes the concept and realization of gene therapy for HIV from the unique historic perspective and insight of two pioneers of the clinical applications of stem cell gene therapy for HIV.
The rapid advances made in the study of the synthesis, structure and function of biological macromolecules in the last fifteen years have enabled scientists concerned with antimicrobial agents to achieve a considerable measure of understanding of how these substances inhibit cell growth and division.
Although the scientific literature on drug metabolism is extensive, it suffers from the disadvantage that the material is diffuse and consists largely of specialist monographs dealing with particular aspects of the subject.