It is less than 80 years since John Newport Langley first proposed the role of "e;receptive substances"e; as the site of drug action from his obser- vations on the effects of nicotine and curare at the myoneural junction.
Volume 9 of Chemical Mutagens consists mainly of chapters discussing the development and validation of short-term assays to detect the mutagenic effects of environmental chemicals.
A few years ago, two of us joined our senior colleague at Pharma- Kinetics Laboratories, a newly public contract research firm just under- taking a major expansion into the clinical trials market.
This document is the result of a conference on "e;Biological Monitoring of Metals"e; held in Rochester, June 2-6, 1986, organized jointly by the Environmental Health Sciences Center of the School of Medicine and Dentistry of the University of Rochester, NY, and the Scientific Committee on the Toxicology of Metals within the International Commission on Occupational Health (ICOH) at the Karolinska Institute and the National (Swedish) Institute of Environmental Medicine and the University of Umea, Sweden.
Although there are over 400,000 people each year in the United States alone who suffer from traumatic injury to the central nervous system (CNS), no phar- macological treatment is currently available.
This volume addresses some facets of the adverse actions of chemical agents on the central and peripheral nervous systems in developing and mature states.
There has been an explosion of research activity related to angiogenesis in recent years, and hundreds of laboratories worldwide are actively involved in many aspects of angiogenesiS.
Wide and fascinating is the field of research on tryptophan, a most versatile amino acid, transformed, as it is, in our organism into many biologically active substances.
This book is based on the proceedings of the symposium entitled "e;Di- rected Drug Delivery: A Multidisciplinary Problem,"e; which was held in Lawrence, Kansas on October 17-19, 1984.
The impetus for this book came from numerous requests by public and private agencies and citizens for information regarding the human health effects of pes- ticide exposures.
Global attention in scientific, industrial, and governmental communities to traces of toxic chemicals in foodstuffs and in both abiotic and biotic environ- ments has justified the present triumvirate of specialized publications in this field: comprehensive reviews, rapidly published progress reports, and archival documentations.
The Complex Variable Boundary Element Method (CVBEM) has emerged as a new and effective modeling method in the field of computational mechanics and hydraulics.
Ivermectin and abamectin, members of the avermectin family of compounds, were introduced to the market in the 1980's as a veterinary antiparasitic drug and agricultural pesticide, respectively.
It has been 80 years since the subject of bacterial adhesion to surfaces was first brought forth, but only in the last two decades has the importance of this subject been recognized by medical microbiologists.
The author has organized basic, core information on the diagnosis, treatment and prevention of chemical dependence into a readily understandable format.
This book entitled Arterial Chemoreception is an edited compilation of the oral communications and posters presented at the IXth International Sym- posium on Arterial Chemoreceptors held in Park City, Utah, from August 29th to September 3rd, 1988.
This two-volume treatise, the collected effort of more than 50 authors, represents the first comprehensive survey of the chemistry and biology of the set of molecules known as peptide growth factors.
Since 1975, the Oklahoma Notes have been among the most widely used reviews for medical students preparing for Step 1 of the United States Medical Licensing Examination.
