Practical Toxicology: Evaluation, Prediction, and Risk, Third Edition shows how to conduct a program of safety evaluation and testing and then to interpret and apply the resulting data and information in the real world, beginning with the basic concepts in toxicology and progressing to the interpretation of the resulting data.
This meticulous volume covers metabolism and drug-drug interactions during pregnancy, critical periods of developmental toxicology, in vivo and alternative methods to assess potential developmental toxicity for drugs and chemicals, and effects of chemicals on testes and mammary glands.
The book delves into the development and therapeutic potential of Sodium-glucose Cotransporter-2 (SGLT2) inhibitors for the treatment of diabetes and cardiovascular diseases.
This new book, drawing on the author's distinguished career in front-line psychiatric practice, describes how to bring patient and prescriber together in an active partnership whereby there is better understanding of the positive and negative elements of drug prescription.
Presenting new developments in sampling and drug profiling, this book also provides practical information on how to carry out analysis, what the results mean and how they can be used as court evidence and for drugs intelligence purposes.
Hot Spot Pollutants describes how pharmaceuticals and/or endocrine active compounds gain entry into the aquatic ecosystem, effects on specific organisms and the potential risk involved for the whole ecosystem.
Nanostructures for Cancer Therapy discusses the available preclinical and clinical nanoparticle technology platforms and their impact on cancer therapy, including current trends and developments in the use of nanostructured materials in chemotherapy and chemotherapeutics.
This detailed book explores protocols for a wide array of preclinical pharmacology and toxicology evaluations to be applied to chemical drugs and their development through in vitro, involving tissues and cell lines, and in vivo models, using animals as experimental systems, utilized to conduct pharmacological research.
This detailed book explores the fundamentals of myofibroblast biology in tissue repair, fibrosis, and tumors as well as providing cutting-edge laboratory methods used to investigate myofibroblast functions in physiological and pathological settings in vitro and in vivo, as written by leading academic scientists.
Nach Definition, Einteilung und Chemie werden in Band 3 Pharmakologie, Neurobiochemie/Wirkmechanismus sowie Klinik (Indikationen, Dosierung, unerwünschte Wirkungen, Interaktionen, Kontrolluntersuchungen, allgemeine Behandlungsrichtlinien) der trizyklischen und nicht-trizyklischen Antidepressiva sowie der Monoaminoxidase-Hemmer und der atypischen Antidepressiva abgehandelt.
In dem Buch werden sowohl von allgemeinärztlicher wie von klinisch-pharmakologischer Seite die Möglichkeiten, aber auch die Grenzen rationaler Arzneimitteltherapie in der primärärztlichen Praxis dargestellt; insbesondere werden die Rahmenbedingungen und Probleme des Umgangs mit Arzneimitteln in der Allgemeinpraxis behandelt, die sich in vielen Bereichen von denen der medikamentösen Therapie im Krankenhaus erheblich unterscheiden.
Clinical Trials and Tribulations evaluates the multiple layers of complexities around research management, also exploring current practices, challenges and future directions.
Comprehensive manual providing clinicians with essential information about the pharmacologic principles and clinical use of all available pain medications.
The book covers recent advances in the field of CNS therapeutics, including opportunities posed by expanding basic knowledge related to CNS conditions and novel approaches for efficient drug delivery to the brain (e.
**Selected for Doody's Core Titles(R) 2024 in Toxicology**The second edition of Forensic Toxicology: Principles and Concepts takes the reader back to the origins of forensic toxicology providing an overview of the largely unchanging principles of the discipline.
This book provides an overview of nanoparticle production methods, scale-up issues drawing attention to industrial applicability, and addresses their successful applications for commercial use.
Molecular Bases of Anesthesia provides a clear overview of the state of knowledge about anesthetic mechanisms at the molecular level of occurrence and focusing on the latest state-of-the-art techniques that relate to how anesthetic drugs cause unconsciousness.
Profiles of Drug Substances, Excipients, and Related Methodology, Volume 46 contains comprehensive profiles of five drug compounds: Darunavir, Bisoprolol, Betaxolol, Rabeprazole and Irbesartan.
The 8th International Congress of Biorheology was held at the Pacifico Yokohama, Japan, a brand new, versatile convention center for international meetings, from August 3 through 8, 1992.
Urticaria is a vexing problem, to the patient who teachers who have stimulated my interest and helped suffers from the annoying pruritus and the fear oflife- me to understand the basic and clinical aspects of mast threatening reactions, to the physician who faces the cell-related problems is long.
Mesenchymal Stromal Cells: Translational Pathways to Clinical Adoption provides the latest information on the necessary steps for successful production of stem cells for a clinical trial.
The Chinese Research Academy of Environmental Sciences (CRAES) has conducted the Environmental exposure related activity pattern research of Chinese population (Adults).
In this book, Murphy brings together a team of international experts to review cutting-edge scientific literature from the field of psychobiology and related disciplines which addresses important questions and broadens our understanding of substance use behaviours.
A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy examines drug carrier development for controlled, targeted, pH and stimuli responsive drug releases for tuberculosis.
Plant extracts or their pure natural constituents have been used traditionally for thousands of years for treating diseases with considerable success in India and other Asian countries.
Barrier, reservoir, target site - those are but some of the possible functions of biological lipid membranes in the complex interplay of drugs with the organism.
Efforts are being made by research organizations and cosmetic industries worldwide to develop more precise and targeted 3D models that mimic humans for testing cosmetic and personal health care product ingredients, following a complete ban on animal testing.
Synthesis of Carbon-Phosphorus Bonds, Second Edition is a working guide for the laboratory, incorporating classical approaches with the recent developments of carbon-phosphorus (C-P) bond formation.
This two-volume treatise, the collected effort of more than 50 authors, represents the first comprehensive survey of the chemistry and biology of the set of molecules known as peptide growth factors.