In this first authoritative overview on modern cancer chemotherapy 121 international specialists have contributed their experience and recent data for what is likely to become the gold standard in the field.
The Core Model: A Collaborative Paradigm for the Pharmaceutical Industry and Global Health Care develops the innovative core model, an organizational research and design paradigm and economic theory that proposes a collaborative approach to resolving global health issues and improving the productivity of drug development.
Continuing a long tradition, Lu's Basic Toxicology, Seventh Edition, provides guidance on principles of toxicology and testing procedures for toxicities as well as a concise yet detailed mechanism of both target organ and non-target organ toxicities.
The International Life Sciences Institute (ILSI) was estab- lished in 1978 to stimulate and support scientific research and educational programs related to nutrition, toxicology, and food safety, and to encourage cooperation in these programs among scientists in universities, industry, and government agencies to assist in the resolution of health and safety issues.
When asked to compare the practice of medicine today to that of a hundred years ago, most people will respond with a story of therapeutic revolution: Back then we had few effective remedies, but now we have more (and more powerful) tools to fight disease, from antibiotics to psychotropics to steroids to anticancer agents.
This superbly written text gives students, residents, and practitioners the edge in understanding the mechanisms and clinical management of acid-base disorders.
This book presents information about the use of technology to support the prevention and management of drug safety issues: pharmacovigilance (PV), medication errors, drug-related problems (DRPs), counterfeit medicines and other drug safety issues.
Practical drug development approaches presented by leading experts Designed to support the development of new, effective therapeutics, Topical and Transdermal Drug Delivery: Principles and Practice explains the principles underlying the field and then demonstrates how these principles are put into practice in the design and development of new drug products.
The Amphipathic Helix is a comprehensive volume discussing amphipathic helices in systems as diverse as serum lipoproteins, lung surfactant, cytotoxic peptides, ion channels, mitochondrial targeting, peptide hormones, G proteins, T-cell recognition, DNA binding proteins, and antifreeze proteins.
A unique, integrated look at solid-phase synthesis and advances in combinatorial chemistry and technologies The last decade has seen a rapid expansion in combinatorial technologies, a field where chemistry disciplines intersect with automation, statistics, and information science, as well as certain biological disciplines.
The first meeting of the NATO/CCMS Pilot Study "e;Dose-Response Analysis and Biologically-Based Risk assessment for Initiator and Promoter Carcinogens"e; was held in Rome, Italy, in the spring of 1991, and was followed by annual or bi-annual meetings held in Germany, Greece, Netherlands, Portugal, USA, up to the end of 1995; in large part supported by NATO/CCMS grants or fellowships, and organized by Pilot Study participants.
Progress in Medicinal Chemistry, Volume 61 provides a review of eclectic developments in medicinal chemistry, with each chapter written by an international board of authors.
Molecular Pharmaceutics and Nano Drug Delivery: Fundamentals and Challenges provides a thorough resource for both beginners and established scientists, bringing fundamental knowledge about key challenges of these carriers down to the molecular level.
The definitive book on the neutralization of recombinant biopharmaceuticals Recombinant biopharmaceuticals are an important tool for treating a range of illnesses; however, their efficacy can be severely impaired by their immunogenicity.
REAL-LIFE CLINICAL CASES FOR THE BASIC SCIENCES AND USMLE STEP 1Experience with clinical cases is key to excelling on the USMLE Step 1 and shelf exams, and ultimately to providing patients with competent clinical care.
Biocontamination Control for Pharmaceuticals and Healthcare outlines a biocontamination strategy that tracks bio-burden control and reduction at each transition in classified areas of a facility.
Toxicology in Antiquity is the first in a series of short format works covering key accomplishments, scientists, and events in the broad field of toxicology, including environmental health and chemical safety.
Chemical Intolerance identifies phenolic (aromatic) chemical compounds present in natural foodstuffs, pollens, certain food additives, tobacco smoke, perfumes, air pollution, etc.
This book highlights the importance of the choroid plexus, which forms the blood-cerebrospinal fluid barrier and is the site of the major production of the cerebrospinal fluid (CSF).
Written by one of the very first practitioners of ICP-MS, Practical Guide to ICP-MS and Other Atomic Spectroscopy Techniques: A Tutorial for Beginners presents ICP-MS in a completely novel and refreshing way.
This updated edition provides research scientists, microbiologists, process engineers, and plant managers with an authoritative resource on basic microbiology, manufacturing hygiene, and product preservation.
This is the first resource to provide researchers in academia and industry with an urgently needed update on drug intervention against trypanosomatides.
This reference/text covers fundamentals of peptide and protein drug delivery, including such considerations as synthesis, physical chemistry and biochemistry, analysis, proteolytic and transport constraints, pharmacokinetics, and pharmacodynamics; bioavailability from routes of administration, detai
