Pharmacology

Rapid advances in computer science, biology, chemistry, and other disciplines are enabling powerful new computational tools and models for toxicology and pharmacology.

The major reason for the elevated costs of drug development in the pharmaceutical industry is the high attrition rate.

Rapid advances in computer science, biology, chemistry, and other disciplines are enabling powerful new computational tools and models for toxicology and pharmacology.

This volume presents 30 state-of-the-art protocols and reviews to set up and apply primary hepatocyte cultures for research and screening purposes.

Spanning from discoveries in fundamental immunology to industrial and commercial concerns, the study of vaccine adjuvants has developed into an exciting area of work with great, vital potential in innovating techniques in which adjuvants may steer the immune system towards the responses required by unmet vaccination needs.

This thorough volume delves into antiepileptic drug discovery with a comprehensive collection of innovative approaches for the development of antiepileptic therapies, focusing on novel molecular targets for antiepileptic drugs, computer-aided approaches for the identification of new drug candidates, and therapeutic strategies to overcome refractory epilepsy.

This is the first comprehensive reference compilation on the substance class of glucosinolates.

DNA Vaccines: Methods and Protocols, Third Edition explores innovative approaches and technologies used to design, deliver, and enhance the efficacy of DNA vaccines.

Understanding an individual's genetic makeup is the key to creating personalized drugs with greater efficacy and safety, and pharmacogenomics aims to study the complex genetic basis of inter-patient variability in response to drug therapy.

Classical natural product chemistry is transitioning to modern day metabolomics as a result of the advent of comprehensive analytical platforms and sensitive analytical instrumentation.

Cytokines in Human Health: Immunotoxicology, Pathology, and Therapeutic Applications explores the role of cytokines in immunotoxicology and human health using a variety of complex methods, from basic research to highly applied therapeutic applications.

DNA Vaccines: Methods and Protocols, Third Edition explores innovative approaches and technologies used to design, deliver, and enhance the efficacy of DNA vaccines.

The only source on the subject to offer both an overview and a disease-based approach, this reference text spans the wide array of technical, methodological, regulatory, and ethical issues related to pharmacogenetics and stresses the impact of pharmacogenetic data on patient care and management.

Unique work on structure-based drug design, covering multiple aspects of drug discovery and development.

The last decade has seen the confluence of several enabling technologies that have allowed protein crystallographic methods to live up to their true potential.

Macromolecular drugs hold the promise of becoming new therapeutics for several major disorders, including cancer and cardiovascular disease.

This work provides rapid access to focused information on topics of Immunotoxicology not only for scientists and those dealing with laboratory aspects but also for lecturers and advanced students.

This handbook, now in a new, second edition, is an essential resource for scientists with an interest in the role of glycosyltransferases and related genes involved in the biosynthesis of glycoproteins, glycolipids, and proteoglycans.

Covering topics from individual molecules to systemic diseases, from basic concepts to advanced technologies, Pharmacogenomics in Drug Discovery and Development , Second Edition provides a practical, state-of-the-art and integrative view of the application of pharmacogenomics in drug discovery and development.

This text provides a practical guide providing step-by-step protocol to design and develop vaccines.

Infectious diseases caused by viruses, parasites, bacteria, and fungi are the number one cause of death worldwide.

G Protein-Coupled Receptor Genetics: Research and Methods in the Post-Genomic Era features practical techniques inspired by the fast moving GPCR field.

In Vitro Toxicology Systems brings together important issues and considerations needed in order to develop a workable, reliable, integrated testing strategy for the replacement of animals in toxicity testing regimes.

This detailed volume aims to introduce nanomaterials as a new therapeutic regimen in treating human diseases.

As the drug discovery process shifts more and more toward specifically targeting pathways and molecules, model systems continue to increase in importance, and the mouse, with its versatility, ease of use, and remarkable similarity to the human genome, has clearly risen to the forefront of animal model studies.

Molecular Toxicology Protocols, Second Edition aims to bring together a series of articles describing validated methods to elucidate specific molecular aspects of toxicology, the emphasis being on the application of molecular methods to genetic toxicology.

DNA has been known to be the cellular target for many cytotoxic anticancer agents for several decades.

Neuro-psychopharmacology

Practical Psychopharmacology, 2nd ed, takes the novel approach of writing at three different levels-beginning, intermediate, and advanced-to give the practicing psychopharmacologist a tailored experience.

As a key component of human survival, a safe and sufficient food supply is essential for a healthy and productive population throughout the world, so assurance that the food supply is clean and free of harmful substances is a global concern.

In Vitro Toxicology Systems brings together important issues and considerations needed in order to develop a workable, reliable, integrated testing strategy for the replacement of animals in toxicity testing regimes.

Liquid-Chromatography-Mass-Spectrometry procedures have been shown to be successful when applied to drug development and analysis.

This book is a comprehensive exploration of the multifaceted role of phytochemicals in contemporary drug discovery and biotechnology.

With significant developments in the areas of chromatography and spectroscopy as well as the unique inherent chemical diversity of natural products, vital in drug research, natural products research has gained new momentum.

La drogadicción es considerada uno de los problemas sociales más apremiantes en la mayoría de las sociedades modernas y les acarrea a estas un elevado costo social y económico, que implica no solo a la sociedad como un todo, sino también a los niños y jóvenes.

"Ha sido una grata sorpresa leer este libro Adicción de mi amigo del alma Juan Carlos García, pues su contenido y conceptos son expresados de manera acertada tanto en la experiencia personal como en lo psicológico, con una claridad producto del trasegar en las capas profundas del alma, con el invariable "dolor de crecimiento" que se nota por parte del autor.

La administracion de medicamentos es una de las intervenciones de cuidado mas frecuentes que realiza el campo de la enfermeria en su rol profesional, y por tanto, de gran impacto para la salud y calidad de vida de la poblacion.

In his late teens, Henry Carmel was stricken with schizophrenia-a life-altering mental illness characterized by tormenting voices, impaired judgment, and acute paranoia.

Toxic Tort: Medical and Legal Elements,provides a primer covering medicaland legal issues involved in toxicsubstances litigation.

Risikoanalysen sind Methoden des Qualitätsrisikomanagements und nehmen eine wichtige Stellung ein.

Nursing pharmacology is a class that nurses are required to take before they receive their licenses.

The book deals with the subject of depression and its causes and answers a number of questions that should be of interest to any and every patient regarding the health-care system and the society in general.

Fun With Pharmacology is a new innovative way to study a really hard class.