Pharmacology

This 2-volume book set, Phytochemistry and Pharmacology of Medicinal Plants, introduces and provides extensive coverage of 79 important medicinal plant species.

From the President of the Research Society on Alcoholism In recent years the alcohol research field has matured and is attracting a substantial number of eager and technically sophisticated researchers.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

The purpose of this book is to introduce the classified chemical components of hypoglycemic compounds in natural products, summarize the recent research progress of natural products with hypoglycemic activity in the past 20 years, and provide the original analysis and development opinions of relevant scholars.

Medicinal Natural Products: A Disease-Focused Approach, Volume 55 in the Annual Reports in Medicinal Chemistry series, highlights the applications of natural products as medicines or prospective medicinal leads for the treatment of various human ailments.

The field of genetic toxicology is a relatively new one which grew out of the studies of chemical mutagenesis and modern toxicology.

Discussing existing techniques, ongoing research, new approaches, and basic concepts in the treatment of nail diseases, Topical Nail Products and Ungual Drug Delivery summarizes the current knowledge and represents a jumping-off point for creating novel techniques of drug delivery across the nail.

During the last decade physical and chemical methods have improved rapidly - a fact which allowed the mode of action of antibiotics to be studied - and many biochemically-oriented scientists have devoted their research to the following questions: 1.

Helps prescribers to easily and rapidly answer questions that may arise when initiating and monitoring an antiepileptic drug.

This volume provides a complete update of all the materials in prior volumes on the subject (including current directories to testing labs and other support establishments worldwide), while adding substantial new material on the following topics:         The history of CROs, including snapshots of CROs and a genealogy chart making clear where they came from and where they went.

Xenobiotics are chemical compounds foreign to a given biological system.

The success of any drug discovery project relies upon the quality of the lead that initiates the lead optimization process.

This book presents recent advances in inorganic nanomaterials for healthcare, with focus on the synthesis, medical applications and toxicity of metals, metal oxides and metal sulfides.

This detailed book showcases recent advances in computational design of multi-target drug candidates involving various ligand and structure-based strategies.

This book focuses on the toxicity of engineered nanomaterials (ENMs) and their underlying physicochemical, cellular, physiological, and molecular mechanisms.

The goal of this book is to provide a guide and detailed review of immunosuppression in terms of molecular mechanisms of action, side effects and clinical trials that validated their utility.

Catecholamines are important transmitter substances in the autonomic and central nervous systems.

The deregulation of dietary supplements and natural products marketing by the FDA has widened the natural products market in Europe and worldwide.

Translating Regenerative Medicine to the Clinic reviews the current methodological tools and experimental approaches used by leading translational researchers, discussing the uses of regenerative medicine for different disease treatment areas, including cardiovascular disease, muscle regeneration, and regeneration of the bone and skin.

This volume features a comprehensive set of protocols featuring a range of both old and new technologies that can be used to analyze drugs of abuse, including prescription drugs, new psychoactive substances and psychoactive plants.

Mangroves with Therapeutic Potential for Human Health: Global Distribution, Ethnopharmacology, Phytochemistry, and Biopharmaceutical Applications explores, for the first time in a book, the exciting potential of mangroves for therapeutic applications in medicine and pharmacology.

Targeting protein degradation using small molecules is one of the most exciting small-molecule therapeutic strategies in decades and a rapidly growing area of research.

Acromegaly is a relatively rare chronic disease.

Biosimilars have the potential to change the way we think about, identify, and manage health problems.

The world's population is growing at an unsustainable rate.

New developments in testosterone therapy are summarized here by internationally renowned experts.

Fibrosis is a condition with globally high unmet medical need, and as such is a highly active area of academic and pharmaceutical research covering multiple treatment targets, organs, tissues and therapeutic approaches.

This book provides an in-depth review on various aspects of canine and feline hypertension.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

This book explores the lively chemistry culture that arose during the 17th century in Colonial New England.

The Stahl''s Illustrated series distils and synthesizes key psychopharmacology concepts into highly illustrated and reader-friendly volumes.

Progress in Medicinal Chemistry

While drug therapies developed in the last 80 years have markedly improved treatment outcomes and the management of some types of cancers, the lack of effectiveness and side effects associated with the most common treatment types remain unacceptable.

For centuries the vast and versatile pharmacological effects of medicinal plants and their constituents have played vital roles in biological, economic, social, spiritual, cultural and physiological well-being.

This book is a core introductory text to the subject of toxicology and the use of toxicological information for risk assessment by chemists.

Hazardous Chemicals: Overview, Toxicological Profile, Challenges, and Future Perspectives offers comprehensive coverage of hazardous chemicals and their routes of exposures, mechanism of toxicity, hazard control measures, handling and storage, emergency guidelines, and safety measures.

As in other volumes in the series, this newest volume conveys up-to-date knowledge in a clear and straightforward manner.

Since the earliest dosage forms to modern drug delivery systems, came a great development and growth of knowledge with respect to drug delivery.

A comprehensive guide to late-life anxiety for all mental health workers, covering recent research and evolving techniques and strategies.

Bioenvironmental Issues Affecting Men's Reproductive and Sexual Health is structured into two parts related to men's reproductive and sexual health with eight sections designed to enable a logical flow of such knowledge.

Hydrogen sulfide (H2S) has emerged as an important gas signalling molecule in a series of organs/tissues, on the diseases of which it plays protective roles, such as proangiogenic effects in ischemic tissues, antiapoptotic effects in the cardiomyocytes, regularization of fatal arrhythmia in myocardial infarction, amelioration of inflammation in autoimmune diseases, modification of neuronal transmission, increase in sodium excretion from the kidney, and amelioration of insulin resistance, etc.

This book offers a comprehensive overview of drug and chemical cellular toxicity, especially concerning the effects of anticancer drugs (cyclophosphamide, methotrexate and phosphamidon) on chromosomes and proteins.

This collection explores detailed experimental protocols necessary for setting up a variety of in vitro cytochrome P450 (CYP) assays that are vital in selecting drug candidates in a drug discovery pipeline.

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The deregulation of dietary supplements and natural products marketing by the FDA has widened the natural products market in Europe and worldwide.

Nanoarchitectonics in Biomedicine describes this new area of nanoscience that has emerged as a major branch of nanoscience.