Pharmacology

Toxicology is a comprehensive text for researchers and graduate students in toxicology and public health.

This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden.

Regularly reviewing the "e;state-of-the-art"e; developments in the antiviral drug research field, this latest volume spans the conceptual design and chemical synthesis of new antiviral compounds.

The Many Faces of RNA is the subject for the eighth SmithKline Beecham Pharmaceuticals Research Symposia.

This book is an an up-to-date survey and summary of present knowledge and future expectations regarding the environmental causes of congenital malformations in human beings, beginning with the earliest discoveries of the 20th century up to the latest ideas and problems at its end, presents views and comments on the progress made over the century in understanding human prenatal maldevelopment.

Non-selective inhibitors of cyclic nucleotide phosphodiesterase (PDE), such as theophylline, have been used extensively since 1958.

In recent years, research has shown the importance of peptides in neuroscience, immunology, and cell biology.

Neurotoxicology: Approaches and Methods provides a unique and comprehensive presentation of the current concepts and state-of-the-art methods for the assessment of neurotoxicity.

Neuropeptide Y (NPY) is a ubiquitous and important messenger in the nervous system, with a wide range of physiological roles.

Rheumatoid arthritis is a bewilderingly complex disease involving the interactions of many, and varied, cell populations and multiple families of low and high molecular mass mediators.

Macrolide Antibiotics: Chemistry, Biochemistry, and Practice, Second Edition explores the discovery of new macrolide antibiotics, their function, and their clinical use in diseases such as cancer, AIDS, cystic fibrosis and pneumonia.

Loomis's Essentials of Toxicology is an introductory text on the science of harmful biologic effects associated with exposures to chemicals of all types.

Information Resources in Toxicology, Third Edition is a sourcebook for anyone who needs to know where to find toxicology information.

In Vitro Methods in Pharmaceutical Research provides a comprehensive guide to laboratory techniques for evaluating in vitro organ toxicity using cellular models.

Hormones and Signaling focuses on the mechanism of gene regulation at the cellular level.

Living cells are constantly sensing environmental changes, and their abilities to sense these changes and adapt to them are essential for their survival.

In the early eighties when the H3 receptor was identified, many thought that an H3 ligand, an agonist or an antagonist, would become available as a therapeutic agent.

This book describes the complex structures of heparins and heparan sulfates (heparinoids) and how they are generated by their biosynthetic pathways.

This reference series will provide all researchers using laboratory animals with comprehensive practical information on the various species.

Genetic Algorithms in Molecular Modeling is the first book available on the use of genetic algorithms in molecular design.

Epilepsy is, after headache, the second most common neurological disorder.

The only comprehensive work to cover all aspects of diuretic agents, the book discusses the pharmacology and toxicology of diuretic agents as well as the physiological effects.

This book is intended to serve as quick reference handbook on so-called designer drugs.

The seventh volume of Advances in Pharmaceutical Sciences heralds a welcome continuation of this well-respected series.

This volume continues the trend for Advances in Drug Research of shorter, but more frequent volumes.

This volume continues the trend for Advances in Drug Research of shorter, but more frequent volumes.

Volume 27, the first thematic volume in the Series, provides an overview of present knowledge with regard to the pharmacological and clinical aspects of antidiabetic drugs.

Volume 26 continues the trend of shorter, more frequent volumes.

This volume continues the trend for Advances in Drug Research of shorter, but more frequent volumes.

DNA sequence specificity is a sub-specialty in the general area of molecular recognition.

Volume 3 of Advances in Antiviral Drug Design is keeping up with the recent progress made in the field of antiviral drug research and highlights five specific directions that have opened new avenues for the treatment of virus infections.

The purpose of the series on Advances in Antiviral Drug Design is to regularly review the "e;state of the art"e; on emerging new developments in the antiviral drug research field, thereby spanning the conceptual design and chemical synthesis of new antiviral compounds, their structure-activity relationship, mechanism and target(s) of action, pharmacological behavior, antiviral activity spectrum, and therapeutic potential for clinical use.

This book is the first definitive overview on adenosine receptor antagonists and their application to the treatment of Parkinson's Disease.

Acute toxicology testing provides the first line of defense against potentially dangerous chemicals.

Quinolones constitute a large class of synthetic antimicrobial agents that are highly effective in the treatment of many types of infectious diseases, particularly those caused by bacteria.

Proteases are enzymes that essentially "e;eat"e; protein.

The subject of aluminium and Alzheimer's disease has been plagued with controversy.

* Up-to-date review on the chemistry and biology of nucleosides* Modern synthetic methodology* Comprehensive coverage of antiviral nucleosidesThis book summarizes the recent advances in nucleosides chemistry and chemotherapy over the past 10-15 years.

Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area-one of great importance to organic chemists, polymer chemists, and many biological scientists.

Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area--one of great importance to organic chemists, polymer chemists, and many biological scientists.

This volume provides extensive health (toxicological) and safety handling information and data on over 1,000 chemicals of commercial and industrial importance.

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press.

Vitamins and Hormones is the longest-running serial published by Academic Press.

Under the capable and qualified editorial leadership of Dr.

Whilst following in the footsteps of previous volumes by presenting comprehensive reviews of drug substances and additional materials, this title also heralds a significant expansion of the scope of the series.

The fourth volume of Advances in Antiviral Drug Design is keeping up with the recent progress made in the broad field of antiviral drug research and encompasses six specific directions that have opened new avenues for the treatment of HIV and other virus infections.

Hot Spot Pollutants describes how pharmaceuticals and/or endocrine active compounds gain entry into the aquatic ecosystem, effects on specific organisms and the potential risk involved for the whole ecosystem.

The Mechanics of Inhaled Pharmaceutical Aerosols, An Introduction provides a unique and comprehensive treatment of the mechanics of inhaled pharmaceutical aerosols.

This volume features accounts of the biological rationale, design and clinical potential of drug molecules; summaries of structure-activity relationships in topical areas of medicinal chemistry and extensive references to the biology, medicinal chemistry and clinical aspects of each topic.

This volume covers contemporary advances in five important areas of pharmacology and medicinal chemistry including: a comprehensive account of inhibitors of the caspase family of proteolytic enzymes that represent a new class of anti-inflammatory and antiapoptotic agents of potential value in rheumatoid arthritis, and other peripheral and central indications; adoc umented survey of semi-synthetic and totally synthetic antibiotics and anti HIV agents and their sites of interaction; inhibitors of the intracellular enzyme acyl-CoA: cholesterol O-acyltransferase (ACAT) developed for the treatment of hypercholesterolemia; and recent progress in growth hormone secretagogues, with the focus on strategies to improve oral bioavailability and duration of action.