To describe principles of optical imaging including chemistry and physics of fluorescence, limitations/advantages of optical imaging compared to metabolic and anatomic imaging.
Highlighting cutting-edge research on human exposure to endocrine toxicants and the related harmful effects, this book focuses on the challenges of dealing with increasing pollution levels, increased use of synthetic chemicals, and environmental endocrine disruptors that endanger the human endocrine system and its hormones.
Clinical Perspectives and Targeted Therapies in Apoptosis: Drug Discovery, Drug Delivery, and Disease Prevention provides comprehensive coverage, from basic cell biology, to modern assessment techniques for apoptosis in all major disease areas.
Case study details the right way and the wrong way to successfully develop and market a new drug Beginning with the untimely death of a young mother, A History of a cGMP Medical Event Investigation unfolds a fictitious case study that captures how unchecked human flaws during the development and launch of a new drug can lead to disastrous consequences.
This monograph brings together the proceedings of a workshop held in Geneva, Switzerland in March 2000 under the joint sponsorship of the University of Sheffield and F Hoffmann La Roche Ltd.
Fully revised and expanded, the second edition of Basic Chemical Concepts and Tables is written as a quick reference to the many different concepts and ideas encountered in chemistry.
The Nobel Prize is the highest award in science, as is the case with nonscience fields too, and it is, therefore, arguably the most internationally recognized award in the world.
Wildlife Toxicity Assessments for Chemicals of Military Concern is a compendium of chemical-specific toxicity information with discussions on the rationale and development of Wildlife Toxicity Reference Values (TRVs) intended for use on terrestrial wildlife for risk assessment applications.
Neurological disorders categorized as neurodegenerative, neuropsychiatric, and neurotraumatic impose a substantial health burden and cause a frail impact on life attributes.
The 9th World Congress on Animal, Plant and Microbial Toxins was sponsored by the International Society on Toxinology which recently celebrated its 25th anniversary.
This is the second edition of a well-received book that reflects the state of the art in cancer medical therapies and their side-effects, including immunotherapy and chemotherapeutic drugs.
Whenever radioactivity is released to the atmosphere, for example by the detonation of nuclear weapons or the testing of nuclear weapons or from nuclear reactor accidents that fraction of it which remains airborne for more than a few hours is liable to be attached to aerosol particles.
Collective knowledge of the origins and pharmacology of pain are evolving rapidly, providing increased hope for better pain management and a far greater quality of life for patients worldwide.
This updated and revised Second Edition provides a state-of-the-science review and clinical collection of research on treating depression with multiple therapies.
With people aged 65 years and older currently making up the fastest growing age group throughout the world, the demographic revolution of an aging society will inevitably lead to increased pressure to develop a rationalistic and age-tailored process of diagnosis and treatment among the elderly.
A consolidated and comprehensive reference on ligand-binding assays Ligand-binding assays (LBAs) stand as the cornerstone of support for definition of the pharmaco-kinetics and toxicokinetics of macromolecules, an area of burgeoning interest in the pharmaceutical industry.
Percutaneous Penetration Enhancers in a mini-series format comprising five volumes, represents the most comprehensive reference on enhancement methods - both well established and recently introduced - in the field of dermal/transdermal drug delivery.
This book is the first to provide both a broad overview of the current methodologies being applied to drug design and in-depth analyses of progress in specific fields.
Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.
The evolution in our understanding of opioid receptors and their subtypes is in- mately linked to the development of new pharmacological treatments for diseases/ disorders as diverse as addiction, self-injurious behavior, pain, cancer, infl- mation, eating disorders, traumatic injury, pruritis, and movement disorders.
Extensive research has uncovered a set of molecular surveillance mechanisms - commonly called "e;checkpoints"e; - which tightly monitor cell-cycle processes.
CRC Handbook of Phytochemical Constituents of GRAS Herbs and Other Economic Plants is a unique catalog that includes more than 15,000 phytochemical constituents from over 1,000 higher plant species.
Diese erste Veröffentlichung über den Stand der Projekte zur Erforschung des menschlichen Genoms setzt sich kritisch mit den ethischen Aspekten der Genomanalyse und Gentherapie in der Humanmedizin auseinander.
Throughout history, the perpetuation of species, the need for survival, and human curiosity, intelligence and skills provided the basis for the development of drug science.
This book covers all aspects of hypersensitivity to drugs, providing practical information for non-specialist physicians as well as addressing issues of interest to practitioners in different specialties and presenting the expert knowledge required by specialist allergists and immunologists.
An indispensable resource for busy researchers Your time is valuable-too valuable to spend hunting through the technical literature in search of the right HPLC assay techniques for your projects.
The Handbook of Pharmaceutical Manufacturing Formulations, Third Edition: Volume Two, Uncompressed Solid Products is an authoritative and practical guide to the art and science of formulating drugs for commercial manufacturing.
Alzheimer disease (AD) has become the most common form of dementia in industrialized countries and represents an increasing burden at the economic, social and medical level.