This detailed volume assembles comprehensive protocols to assist with the study of structural, molecular, cell biological, and in vivo facets of GPCRs, and to enable the development of experimental tools for screening novel GPCR drugs.
This detailed volume collects numerous methods and protocols related to different aspects of stability programs that are followed in pharmaceutical development laboratories.
In Vitro Toxicology Systems brings together important issues and considerations needed in order to develop a workable, reliable, integrated testing strategy for the replacement of animals in toxicity testing regimes.
Well-respected leaders in the field of in vitro neurotoxicology take a fresh look at their own and other's work, critically and comparatively analyzing it across experimental systems and toxicants, and synthesizing essential principles for in vitro neurotoxicity testing.
This book explores well-established and emerging conjugation strategies that are relevant for proteins used in the field of precision medicine, focusing on techniques that are suitable for antibodies, antibody-fragments such as Fabs, scFvs, or nanobodies, scaffold proteins such as FN3 or DARPin, peptides, or model proteins.
Due to the importance of potassium channels in cellular function, researchers have been challenged to develop tools and experimental procedures to probe the function and identify chemicals that modulate the behaviour of this super-family of ion channels.
Advanced Nanoformulations: Theranostic Nanosystems, Volume Three examines the applications of nanotherapeutic systems and nanodiagnostics in relation to polymeric nanosystems.
Oxidative damage appears to play a central role in the development of a wide range of tissue pathology, including neurodegenerative disease, drug side-effects, xenobiotic toxicity, carcinogenesis, and the aging process, to name just a few.
This detailed book serves to provide a global overview of the goals, rationale, and scientific basis for malaria control and elimination, as well as tools, methods, and strategies to that end.
Animal Cell Biotechnology: Methods and Protocols, Second Edition constitutes a comprehensive manual of state-of-the-art and new techniques for setting up mammalian cell lines for production of biopharmaceuticals, and for optimizing critical parameters for cell culture considering the whole cascade from lab to final production.
This book provides a collection of microphysiological systems employed for chemical/drug screening and strategies to mimic various physiological conditions.
Forty years after the term "e;affinity chromatography"e; was introduced, this mode of chromatography remains a key tool in the armory of separation techniques that are available to separation and interaction scientists.
In Therapeutic Applications of Ribozymes and Riboswitches: Methods and Protocols, expert researchers in the field provide a complete overview of protocols used in the development of RNA molecule as drugs and drug target.
Biocompatibility Protocols for Medical Devices and Materials provides comprehensive coverage of the basic science and toxicological testing protocols necessary for the risk assessment and safety analysis of medical devices and materials which are based on the ISO guidelines for body contact and duration of contact.
This book provides a comprehensive overview of and state-of-art information on the production and application of second- and third-generation bioplastics, such as polylactic acid (PLA) and polyhydroxyalkanoates (PHAs).
Medicinal Agroecology: Reviews, Case Studies, and Research Methodologies presents information on applications of 'green therapies' in restoration towards global sustainability.
This book provides a comprehensive overview of and state-of-art information on the production and application of second- and third-generation bioplastics, such as polylactic acid (PLA) and polyhydroxyalkanoates (PHAs).
Pharmacology in Drug Discovery and Development: Understanding Drug Response, Third Edition is an introductory resource that illustrates how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action.
Medicinal Agroecology: Reviews, Case Studies, and Research Methodologies presents information on applications of 'green therapies' in restoration towards global sustainability.
Approaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics provides the interested and informed reader with an overview of current approaches, strategies and considerations relating to the purification, analytics and characterization of therapeutic antibodies and related molecules.
This book focuses on the topic of ecotoxicology of aquatic macrophytes and is wide ranging, including the use of macrophytes for remediation of contaminated sites.
Polymers for Controlled Drug Delivery addresses the challenges of designing macromolecules that deliver therapeutic agents that function safely and in concert with living organisms.
Polymers for Controlled Drug Delivery addresses the challenges of designing macromolecules that deliver therapeutic agents that function safely and in concert with living organisms.
This book presents a complete overview of the main EEG-based Brain-Computer Interface (BCI) paradigms and the related practical solutions for their design, prototyping, and testing.
This book focuses on the topic of ecotoxicology of aquatic macrophytes and is wide ranging, including the use of macrophytes for remediation of contaminated sites.
