Pharmacology

Bioassay Methods in Natural Product Research and Drug Development contains the proceedings from the Phytochemical Society of Europe's very successful symposium on this topic, held August 24-27, 1997 in Uppsala, Sweden.

Despite their effectiveness in the evaluation of new pharmacological compounds, controlled clinical trials are sometimes inadequate.

The purpose of this dictionary is to provide a convenient and affordable personal desk reference resource.

ACE inhibitors are one of the most exciting and interesting of recent medical developments.

This book is intended for students of medicine, pharmacy and other biological disciplines, who want to have a working knowledge of the mechanisms of action, uses and adverse effects of drugs which modify the activity of neurotransmitters in the peripheral and central nervous systems.

This book contains a selection of the papers presented at the meeting "e;Between Clone and Clinic"e; which was organised in March 1990 in Amsterdam by the dutch Organisation for Applied Research, TNO, and the University of Utrecht.

Charles Ernest Overton's 1901 monograph Studien aber die Narkose has become a scientific classic in a number of different fields.

This classic work by Poucher, first published in 1923, was last produced in three volumes titled, respectively The Raw Materials of Perfumery (seventh edition, 1974), The Production, Manufacture and Application of Perfumes (eighth edition, 1974) and Modern Cosmetics (eighth edition, 1974).

It was over five years ago that the Centre for Medicines Research organized a workshop entitled "e;Quality of Life: Assessment and Application"e;.

The contents of this book represent papers which were presented at the Third International Meeting on "e;Side-Effects of Anti-Inflammatory and Analgesic Drugs"e; which was held under the auspices of the University of Verona, Institute of Pharmacology in Verona on 8-11 May 1991.

NEUROTOX '91 was the fourth meeting in a series which started in 1979.

The complement system is a group of proteins which plays a major role in the processing and removal of microorganisms and tissue breakdown products from the circulation and extracellular spaces.

This book includes the most significant contributions of the First International Symposium on "e;Multiple risk factors in cardiovascular disease"e;, chaired by Professors A.

This book is aimed at those in the biomedical community that are interested in the therapeutic applications, pharmacology, biochemistry, toxicology and pharmacokinetics of the title compounds.

Organized on a product category basis, this volume provides an up-to-date review of the cosmetics and toiletries industry in a readily digestible form.

Nicotine is an alkaloid which is present, together with a number of minor alkaloids, in tobacco and a wide variety of other plants.

Currently one of the hottest topics in biochemistry, the concept of molecular chaperones has challenged the paradigm of protein self-assembly.

This volume contains the Proceedings of the invited lectures of the Second International Sym- posium on SEROTONIN from Cell Biology to Pharmacology and Therapeutics held in Houston, Texas September 15-18, 1992.

Although the importance of calcium (Ca2+) in the maintenance of cardiac contractility was recognized as early as 1880, the critical role of the ion in the contractile process in skeletal, cardiac, and smooth muscle has only been established within the last three decades.

Over the past twelve years, the Centre for Medicines Research has held a series of Workshops on a number of topics related to the drug discovery and development process.

For a research-based pharmaceutical company to be successful in the 1990s.

Helicobacter pylori has attracted widening interest from basic scientists and clinical investigators and the information on this organism is increasing exponentially.

Molecular similarity searching is fast becoming a key tool in organic chemistry.

The discovery of the antitumour activity of cisplatin in 1965 and its subsequent introduction into clinical trials in 1971 was the catalyst for a major international research effort investigating the potential of metal compounds in cancer therapy.

Few topics in women's medicine today are as fraught with confusion and controversy as the question of appropriate treatment for menopausal symptoms and the prevention of negative long term health outcomes common to post-menopausal women.

This book is an up-to-date review of current knowledge in the field of multiple drug resistance in human cancer.

Can drug development and evaluation be improved by the use of positron emission tomography (PET)?

As the number of drugs acting on calcium and potassium channels grows, there is a need for a continuous reappraisal of the cellular machinery controlling them.

These two volumes contain the proceedings of a 3 day international meeting held at the University of Cambidge and Queens' College Cambridge from 31st July to 2nd August 1985 on the Side-Effects of Anti-Inflammatory Analgesic Drugs.

The voluminous literature on prostaglandins includes some excellent reviews.

In 1971, Vane proposed that the mechanism of action of the aspirin-like drugs was through their inhibition of prostaglandin biosynthesis.

The authors have taught statistics and given statistics workshops in France and the Netherlands for almost 4 years by now.

Although this is a handbook for policy and regulation, the major part of it is filled with data on the three heavy metals that served as examples: mercury, cadmium and lead.

Ever since the industrial revolution, large numbers of environmentally hazardous materials are in- troduced into the global environment annually; a list of all substances which are at present re- garded as environmentally hazardous might contain thousands of compounds, and new substan- ces are still being added.

The publication of this volume, which is based upon presentations made to the Third European Symposium on Radiopharmacology at Noordwijkerhout, April 22 - 24, 1982, is indicative of the continued interest in this sub-branch of Nuclear Medicine.

The Workshop series of the "e;Koningin Wilhelmina Fonds"e; is a feature of the interest of this Foundation to promote research and education in the field of cancer, aiming to improve prognosis of the cancer patient.

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Safety and efficacy of radiopharmaceuticals are elements of great importance in nuclear medicine.

Ever since Rachel Carson's Silent Spring, we have generally become aware of environmental contaminants and their effects on the ecosystem.

This volume focuses exclusively on those endocytic processes that sequester proteins by a selective, receptor-mediated mechanism.

Aureolus Theophrastus Bombastus von Hohenheim (1493-1541), commonly called Paracelsus, was both one of the most original medical thinkers of the sixteenth century and was the man who made opium (as laudanum), arsenic, copper sulphate, iron, lead, mercury, potassium sulphate, and sulphur part of the pharmacopoeia.

In any textbook, basic scientific knowledge, and the art of clinical practice should be brought together in a rational manner and this volume on cardio- vascular therapy attempts to achieve this aim.