Medical research

Substance use disorder is a legitimate medical disorder with its locus in the pleasure centers of the brain.

This book is a volume in the Penn Press Anniversary Collection.

In Incurable Me, a maverick physician brings transparency to some of medicines most closely guarded secrets.

This book is a comprehensive exploration of the multifaceted role of phytochemicals in contemporary drug discovery and biotechnology.

Cereal grains are a major part of the global diet, but their nutritional benefits depend on how they are processed.

This book reviews the evolving field of epigenetics and its implications for drug discovery and precision medicine.

This book is a comprehensive compilation of over 100 natural and alternative cancer treatments.

This edited book contains chapters that describe bespoke three-dimensional (3D) printing aimed at democratizing anatomy education by providing open-source scans for download and printing as 3D models.

Post-Concussion Syndrome: An Evidence Based Approach surveys the research on this disorder.

This volume provides an introduction to the process of clinical drug development.

Praise for the first edition:"e;Given the author's years of experience as a statistician and as a founder of the first DMC in pharmaceutical industry trials, I highly recommend this book-not only for experts because of its cogent and organized presentation, but more importantly for young investigators who are seeking information about the logistical and philosophical aspects of a DMC.

Highly recommended by CHOICE, Oct 2018Extremophiles are nature's ultimate survivors, thriving in environments ranging from the frozen Antarctic to abyssal hot hydrothermal vents.

Mathematical and Statistical Skills in the Biopharmaceutical Industry: A Pragmatic Approach describes a philosophy of efficient problem solving showcased using examples pertinent to the biostatistics function in clinical drug development.

Dynamic Treatment Regimes: Statistical Methods for Precision Medicine provides a comprehensive introduction to statistical methodology for the evaluation and discovery of dynamic treatment regimes from data.

Review of the First Edition"e;The goal of this book, as stated by the authors, is to fill the knowledge gap that exists between developed statistical methods and the applications of these methods.

Barasi's Human Nutrition: A Health Perspective, Third Edition, provides a comprehensive introduction to the principles and practice of nutrition.

In recent years, many pharmaceutical companies and clinical research organizations have been focusing on the development of traditional Chinese (herbal) medicines (TCMs) as alternatives to treating critical or life-threatening diseases and as pathways to personalized medicine.

Fundamental Concepts for New Clinical Trialists describes the core scientific concepts of designing, data monitoring, analyzing, and reporting clinical trials as well as the practical aspects of trials not typically discussed in statistical methodology textbooks.

Sarcopenia: Molecular, Cellular, and Nutritional Aspects describes the progressive loss of skeletal muscle mass and strength, defined by Rosenberg in 1997 as a hallmark of aging and referred to as "e;sarcopenia.

Cancer is a major healthcare burden across the world and impacts not only the people diagnosed with various cancers but also their families, carers, and healthcare systems.

While medical professionals continue to practice traditional allopathic medicine, the public has turned toward nutritional and integrative medical therapies, especially for addressing the proliferation of chronic diseases.

Eating disorders are among the most complex disorders to treat, typically requiring medical, nutritional, and psychotherapeutic interventions.

Diet is a major factor in health and disease.

Psoriasis is a life-long chronic autoimmune disease characterized by thick scaly skin lesions and often associated with severe arthritis.

Biofortification, which can be defined as the process of increasing the content/density of essential nutrients and/or its bioavailability of food with valuable compounds, is a promising means of increasing nutrient intakes.

Non-communicable diseases (NCDs) are chronic diseases of long duration and generally slow progression, including cardiovascular diseases, cancers, chronic respiratory diseases, and diabetes.

Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials is the first book focused on the application of generalized linear mixed models and its related models in the statistical design and analysis of repeated measures from randomized controlled trials.

There is a compelling need for new drugs and efficient treatments against mosquito-borne diseases.

This book addresses various clinical and sub clinical applications of antioxidant nutraceuticals, with a primary focus on preventive use for general wellness, common ailments, and such chronic illnesses as cancer and neurological applications.

Clinical Trial Optimization Using R explores a unified and broadly applicable framework for optimizing decision making and strategy selection in clinical development, through a series of examples and case studies.

This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach.

Short Bowel Syndrome: Practical Approach to Management is the first reference exclusively about the issues experienced by patients with a short bowel.

Childhood obesity has reached epidemic proportions in the United States and continues to increase in prevalence in almost all countries in which it has been studied, including developed and developing countries around the globe.

Cluster Randomised Trials, Second Edition discusses the design, conduct, and analysis of trials that randomise groups of individuals to different treatments.

Obesity and eating disorders have stubbornly refused to respond to treatment since the 1990's.

All the Essentials to Start Using Adaptive Designs in No TimeCompared to traditional clinical trial designs, adaptive designs often lead to increased success rates in drug development at reduced costs and time.

The role of green coffee bean (GCB) in human health is of emerging interest to the nutraceutical field, especially given its role in improving metabolic syndrome, including weight management, hypertension, diabetes, and neuroprotection.

Cobalamin (vitamin B12) was discovered in the first half of the 20th century.

Cancer Clinical Trials: Current and Controversial Issues in Design and Analysis provides statisticians with an understanding of the critical challenges currently encountered in oncology trials.

Reliably optimizing a new treatment in humans is a critical first step in clinical evaluation since choosing a suboptimal dose or schedule may lead to failure in later trials.

Nutrition plays a key role in prevention of cardiovascular disease, the leading cause of death worldwide.

In a global clinical development strategy, multiregional clinical trials (MRCTs) are vital in the development of innovative medicines.

Develop Effective Immunogenicity Risk Mitigation StrategiesImmunogenicity assessment is a prerequisite for the successful development of biopharmaceuticals, including safety and efficacy evaluation.

Today, bread supplies over half of the caloric intake of the world's population including a high proportion of the intake of Vitamins B and E.

This book provides a resource of current understandings about various aspects of the biology of spermatogonia in mammals.

This text for advanced undergraduate and graduate students covers the fundamental relationships between the structure and properties of materials and biological tissues.

This book provides a resource of current understandings about various aspects of the biology of spermatogonia in mammals.

Involved in nearly every therapeutic area, particularly cancer, biomarkers have experienced tremendous advances since the first edition of this book, both in the discovery of biomarkers and in their applications.

This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date.

This book addresses electron spin-qubit based quantum computing and quantum information processing with a strong focus on the background and applications to EPR/ESR technique and spectroscopy.