Medical research

Molecular Surgical Pathology provides a concise review of recent advancement of molecular pathology in each organ system.

Ischemic heart disease is the leading cause of morbidity and mortality in the developed world.

A vast number of diagnostic and therapeutic decisions are based on measuring blood concentrations of molecules, yet most biochemical and pharmacological events actually take place in the tissues.

This book was written by many outstanding investigators who have spent decades to study different aspects of blood tissue barrier function.

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The enormous potential of siRNA as a therapeutic has led to an explosion of interest from the scientific community.

This is the second edition of this proceedings.

Long acting veterinary formulations play a significant role in animal health, production and reproduction within the animal health industry.

Micro and Nano Flow Systems for Bioanalysis addresses the latest developments in biomedical engineering at very small scales.

This book is devoted to the graphics of patient data: good graphs enabling straight forward and intuitive interpretation, efficient creation, and straightforward interpretation.

Oral Cytology: A Concise Guide provides a state-of-the-art review of the major issues specific to the field of oral cytology.

This book details recent findings in the field of cave microbiology and builds on fast-paced efforts to exploit an unconventional and underexplored environment for new microorganisms which may provide an untapped source of drugs: microorganisms from caves.

This book summarizes present knowledge of different mechanisms involved in the development of positive and negative consequences of cardiac adaptation.

Angiogenesis is a highly complex phenomenon where new blood vessels are formed for the supply of oxygen and nutrients in different organs of the body.

This book is based on a study of referees' reports and letters from journal editors on reasons why papers written by non-native researchers are rejected due to problems with English (long sentences, redundancy, poor structure etc).

Developments in the area of biomaterials, bionanotechnology, tissue engineering, and medical devices are becoming the core of health care.

The book aims to introduce the reader to the emerging field of Evolutionary Systems Biology, which approaches classical systems biology questions within an evolutionary framework.

Tremor is intimately linked to the numerous interactions of the central and peripheral nervous system components tuning motor control, from the cerebral cortex up to the peripheral effectors.

Systems Biology of Apoptosis summarizes all current achievements in this emerging field.

This 2nd edition begins with an overview of NMR development and applications in biological systems.

This book is a collection of articles written by prominent scientists who gathered in the city of Recife, Brazil, 23-27 October 2010, celebrating the 10th International Symposium on Yersinia.

This volume illustrates the functional properties of NAbs.

The Systems Biology of Parkinson's Disease will be underpinned by new measurement techniques.

This new SpringerBrief in Physiology explores the newest research findings on how exercise influences the fetus in utero and beyond.

Editors hope that Regenerative Biology of the Spine and Spinal Cord appeals to the nostalgic sentiments of investigators and intellectuals in that it can be held in hand and provide a broad survey of leading edge science.

Mitochondrial cytopathies are mutations in the inherited maternal mitochondrial genome, or the nuclear DNA-mutation.

Treatment of glioma is currently one of the most challenging problems in oncology, as well as in neurosurgery.

The central theme running through this volume on New Technologies for Toxicity Testing is the development and application of advanced techniques for cell and tissue culture, as well as new markers and endpoints of toxicity, as alternatives to the traditional paradigm of relying on data from laboratory animal tests to undertake labelling and risk assessment.

Among the many GPCRs discovered, the calcitonin family of receptors comprise of members that regulate a number of physiological processes and are involved in many pathological conditions.

This collection of reviews will be of considerable interests to biologists and MDs working on any aspect of cardiovascular function.

Written to satisfy a wide audience, from basic scientist to clinical researcher, this volume explores such varied concepts as: the influence of CBF in the pathotrajectory of TBI, modeling TBI as a means to understand underlying pathological states associated with brain injury victims, disrupted vasculature following head trauma and advanced imaging techniques, vasoreactive substances underlying disrupted blood flow, the role of age and sex on injury outcome, and the latest pre-clinical rationale for focusing on CBF and strategies to improve blood flow as a means to improve outcome in patients suffering the effects of TBI.

This volume has a strong focus on homo-oligomerization, which is surprisingly common.

This timely book covers the need to know clinical practices for all those involved in molecular laboratory science.

Computational modeling is emerging as a powerful new approach to study and manipulate biological systems.

Increasing demand for and awareness of the applications of nanotechnology in medicine has resulted in the emergence of a new fast-growing multidisciplinary area - nanomedicine.

The study of electrochemical nanotechnology has emerged as researchers apply electrochemistry to nanoscience and nanotechnology.

In 1960 Sir Frank Macfarlane Burnet received the Noble Prize in Physiology and Medicine.

This book is being planned as a tribute to Dr.

Detailed characterization of fuzzy interactions will be of central importance for understanding the diverse biological functions of intrinsically disordered proteins in complex eukaryotic signaling networks.

The editor of this volume, having research interests in the field of ROS production and the damage to cellular systems, has identified a number of enzymes showing OH scavenging activities details of which are anticipated to be published in the near future as confirmatory experiments are awaited.

Current thinking holds that obesity derives primarily from overnutrition (though compelling arguments for other mechanisms, like endocrine disruption by environmental pollutants, also gain support from the literature).

Breast and prostate cancers are both hormone-dependent, at least in some stages of their progression.

From the preface: "e;Neural Metabolism In Vivo aims to provide a comprehensive overview of neurobiology by presenting the basic principles of up-to-date and cutting-edge technology, as well as their application in assessing the functional, morphological and metabolic aspects of the brain.

Biological systems are an emerging discipline that may provide integrative tools by assembling the hierarchy of interactions among genes, proteins and molecular networks involved in sensory systems.

This Brief discusses key statistical concepts that facilitate the inferential analysis of data collected from a group of individuals participating in a pharmaceutical clinical trial, the estimation of their clinical significance in the general population of individuals likely to be prescribed the drug if approved, and the related decision-making that occurs at both the public health level (by regulatory agencies when deciding whether or not to approve a new drug for marketing) and the individual patient level (by physicians and their patients when deciding whether or not the patient should be prescribed a drug that is on the market).

Caveolae are 50-100 nm flask-shaped invaginations of the plasma membrane that are primarily composed of cholesterol and sphingolipids.

Diagnostic and Therapeutic Ultrasound has recently taken an explosive growth for better safer, economic, mobile and high quality healthcare.

In today's hospitals, the gap between technology and medicine constantly needs to be bridged, both by physicians and engineers.

It is impossible not to ask ourselves how to cope with the role and impact of scientific research in teaching and learning.

Long acting injections and implants improve therapy, enhance patient compliance, improve dosing convenience, and are the most appropriate formulation choice for drugs that undergo extensive first pass metabolism or that exhibit poor oral bioavailability.