The interdisciplinary field of molecular systems biology aims to understand the behavior and mechanisms of biological processes composed of individual molecular components.
This book highlights the challenges facing quality assurance/quality control (QA/QC) in today's biopharmaceutical environment and presents the strategic importance and value generated by QA/QC for their involvement in control of manufacturing.
The refined pathophysiologal understanding of the heart failure syndrome together with the surge of new technological advances led to innovative medical and interventional treatment strategies improving the outcome of heart failure patients.
The main objective of Cardiac Remodeling: Molecular Mechanisms is to summarize the major research advances in molecular, biochemical and translational aspects of cardiac remodeling over the last 2 to 3 decades under one cover and touch on future directions.
This book addresses the role of tandem repeat polymorphisms (TRPs) in genetic plasticity, evolution, development, biological processes, neural diversity, brain function, dysfunction and disease.
In recent years, a number of groundbreaking structural and mechanistic studies deepened our understanding of helicase mechanisms and established new approaches for their analyses.
This volume, written by experts in the field, discusses the current understanding of the biophysical principles that govern RNA folding, with featured RNAs including the ribosomal RNAs, viral RNAs, and self-splicing introns.
A vast number of diagnostic and therapeutic decisions are based on measuring blood concentrations of molecules, yet most biochemical and pharmacological events actually take place in the tissues.
This book is devoted to the graphics of patient data: good graphs enabling straight forward and intuitive interpretation, efficient creation, and straightforward interpretation.
This book details recent findings in the field of cave microbiology and builds on fast-paced efforts to exploit an unconventional and underexplored environment for new microorganisms which may provide an untapped source of drugs: microorganisms from caves.
This book summarizes present knowledge of different mechanisms involved in the development of positive and negative consequences of cardiac adaptation.
This book is based on a study of referees' reports and letters from journal editors on reasons why papers written by non-native researchers are rejected due to problems with English (long sentences, redundancy, poor structure etc).
The book aims to introduce the reader to the emerging field of Evolutionary Systems Biology, which approaches classical systems biology questions within an evolutionary framework.
Tremor is intimately linked to the numerous interactions of the central and peripheral nervous system components tuning motor control, from the cerebral cortex up to the peripheral effectors.
This book is a collection of articles written by prominent scientists who gathered in the city of Recife, Brazil, 23-27 October 2010, celebrating the 10th International Symposium on Yersinia.
Editors hope that Regenerative Biology of the Spine and Spinal Cord appeals to the nostalgic sentiments of investigators and intellectuals in that it can be held in hand and provide a broad survey of leading edge science.
The central theme running through this volume on New Technologies for Toxicity Testing is the development and application of advanced techniques for cell and tissue culture, as well as new markers and endpoints of toxicity, as alternatives to the traditional paradigm of relying on data from laboratory animal tests to undertake labelling and risk assessment.
Among the many GPCRs discovered, the calcitonin family of receptors comprise of members that regulate a number of physiological processes and are involved in many pathological conditions.
Written to satisfy a wide audience, from basic scientist to clinical researcher, this volume explores such varied concepts as: the influence of CBF in the pathotrajectory of TBI, modeling TBI as a means to understand underlying pathological states associated with brain injury victims, disrupted vasculature following head trauma and advanced imaging techniques, vasoreactive substances underlying disrupted blood flow, the role of age and sex on injury outcome, and the latest pre-clinical rationale for focusing on CBF and strategies to improve blood flow as a means to improve outcome in patients suffering the effects of TBI.
