Translational Medicine: Tools and Techniques provides a standardized path from basic research to the clinic and brings together various policy and practice issues to simplify the broad interdisciplinary field.
In the past thirty years, significant advances have been made in the field of reproductive biology in unlocking the molecular and biochemical events that regulate spermatogenesis in the mammalian testis.
This book of the series on "e;Advances in Biochemistry in Health and Disease"e; includes state-of-the-art information on the status of renin-angiotensin system (RAS) in the form of 24 chapters.
This book, the second volume of Crime Scene Management in Forensic Sciences, reviews the role and impact of forensic evidence in criminal investigations.
This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair.
This entry in the series Pediatric Cancer offers comprehensive information on a variety of cancers, concentrating on brain tumors, the most common solid tumors and the leading cause of cancer-related mortality in children.
This book aims to gather the current knowledge regarding different aspects of brain and spinal cord tumors in order to more efficiently help the patients.
A thorough treatment of the statistical methods used to analyze doubly truncated data In The Statistical Analysis of Doubly Truncated Data, an expert team of statisticians delivers an up-to-date review of existing methods used to deal with randomly truncated data, with a focus on the challenging problem of random double truncation.
This book focusses on evolutionary, structural and functional aspects of pore-forming proteins, bringing together prominent researchers in the fields of structural biology and cellular and biophysical techniques.
Organs and tissues that can tolerate little or no inflammation have developed multiple overlapping mechanisms of immune protection in the absence of inflammation.
Originally confused with opioid receptors and then orphan receptors with no biological function, Sigma Receptors are now recognized as relevant to many degenerative diseases with remarkable potential as therapeutic targets.
Matrix metalloproteinases (MMPs) have been established as promising biomolecular targets for novel drug design and discovery against numerous major disease conditions including various cancers, cardiovascular, neurodegenerative, inflammatory diseases, and more.
As governments and health care systems direct more attention and resources to treating the rising rates of obesity worldwide, one thing has become very clear: obesity is best treated as a chronic condition.
The third edition of this best-selling book continues to offer a user-friendly, step-by-step introduction to all the key processes involved in bringing a drug to the market, including the performance of pre-clinical studies, the conduct of human clinical trials, regulatory controls, and even the manufacturing processes for pharmaceutical products.
Small-Animal SPECT Imaging is an edited work derived from the first workshop on Small-Animal SPECT Imaging held January 14-16, 2004 at the University of Arizona, Tucson, AZ, USA.
Statistical Methods for Survival Trial Design: With Applications to Cancer Clinical Trials Using R provides a thorough presentation of the principles of designing and monitoring cancer clinical trials in which time-to-event is the primary endpoint.
That residues of pesticide and other "e;foreign"e; chemicals in food- stuffs are of concern to everyone everywhere is amply attested by the reception accorded previOUS volumes of "e;Residue Reviews"e; and by the gratifying enthusiasm, sincerity, and efforts shown by all the in- dividuals from whom manuscripts have been solicited.
The book illustrates how biostatistics may numerically summarize human genetic epidemiology using R, and may be used successfully to solveproblems in quantitative Genetic Epidemiology Biostatistics for Human Genetic Epidemiology provides statistical methodologies and R recipes for human genetic epidemiologic problems.
Das besondere Anliegen dieses Bandes besteht darin, altersspezifische Krankheiten mit molekulargenetischen Methoden zu charakterisieren und - soweit heute bekannt - auf ihre molekularen Ursachen zurückzuführen mit dem Ziel, präventive ärztliche Interventionen abzuleiten bzw.
The Temporal Lobe, Volume 187 covers the exponential growth of studies on the relationships between brain and language/cognition, many of which involved the temporal lobe.
Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.
We are extremely pleased that all of the chapters in this volume provide up-to-date information on a variety of topics of interest to scientists working on membrane biology.
This book covers the wide set of well-regulated virulence factors and defense mechanisms of Pseudomonas aeruginosa focusing on stress responses and the evolution of this opportunistic human pathogen.
Individual Participant Data Meta-Analysis: A Handbook for Healthcare Research provides a comprehensive introduction to the fundamental principles and methods that healthcare researchers need when considering, conducting or using individual participant data (IPD) meta-analysis projects.