In proving the existence of stem cells, Ernest Armstrong McCulloch and James Edgar Till formed the most important partnership in Canadian medical research since Frederick Banting and Charles Best, the discoverers of insulin.
Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics Tarik Regad, The John van Geest Cancer Research Centre, Nottingham Trent University, UK, Thomas J.
If we will ever achieve Paul Ehrlich's "e;magic bullet,"e; that is, a molecule which goes with high selectivity to the therapeutic target site, does what it needs to do, and is subsequently cleared from the body, the practice of safety assessment will have to change.
Technological Systems in the Bio Industries: An International Study represents a comprehensive, interdisciplinary, and systematic effort to understand the nature and role of technological change in a rapidly evolving arena of economic activity that can be loosely referred to as the bio industries.
A vast number of diagnostic and therapeutic decisions are based on measuring blood concentrations of molecules, yet most biochemical and pharmacological events actually take place in the tissues.
Provides immediate help for anyone preparing a biomedical paper by givin specific advice on organizing the components of the paper, effective writing techniques, writing an effective results sections, documentation issues, sentence structure and much more.
Neuropalliative Care, Part One, Volume 190 covers a type of care that is given when there is no cure for the neurological disorder and the patient is in distress.
This book provides a comprehensive, state-of-the art review of the genitourinary tumor pathology field and the most contemporary insights regarding specimen submission, histologic morphology, immunohistochemistry, and molecular studies useful in the diagnosis of genitourinary neoplasms.
This essential guide on subgroup analyses in the emerging area of personalized medicine covers the issues of subgroup analyses from a practical and a theoretical/methodological point of view.
Symposium on the Rehabilitation of the Cancer Disabled provides information pertinent solutions provided for disabilities of various kinds, created by the cancerous diseases in different parts of the body.
Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials is the first book focused on the application of generalized linear mixed models and its related models in the statistical design and analysis of repeated measures from randomized controlled trials.
Tissue Engineering and Regeneration in Dentistry: Current Strategies presents a thorough update on the current advances, methods and understanding in tissue engineering in dentistry.
Bayesian Precision Medicine presents modern Bayesian statistical models and methods for identifying treatments tailored to individual patients using their prognostic variables and predictive biomarkers.
In contemporary research, the supercomputer now ranks, along with radio telescopes, particle accelerators and the other apparatus of "e;big science"e;, as an expensive resource, which is nevertheless essential for state of the art research.
Rosenberg's Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Seventh Edition provides a comprehensive introduction and reference to the foundations and practical aspects relevant to the majority of neurologic and psychiatric disease.
The aim of this book is to present a unique compilation of lectures given by international speakers at the Hammersmith Hospital during the recent Meetings in Hepato-Pancreato-Biliary and Transplantation.
Regression Methods for Medical Research provides medical researchers with the skills they need to critically read and interpret research using more advanced statistical methods.
The present book on Molecular & Diagnostic Imaging and Treatment Strategies of ovarian cancer is one of two companion books with the second one being focused on Cell and Molecular Biology of Ovarian Cancer.
Explores the evidence for collaboration-based approaches to improving healthcare, focusing on quality improvement collaboratives and communities of practice.
Review of the First Edition"e;The goal of this book, as stated by the authors, is to fill the knowledge gap that exists between developed statistical methods and the applications of these methods.
Like the geological treasures that surely must lie below the Athabasca glacier, some of the answers to key questions about the control of respiration remain buried.
This new volume, Nanomedicine for the Treatment of Disease: From Concept to Application, looks at the application of nanomedicines with a particular focus on their use in the treatment of diseases.
Oligonucleotides represent one of the most significant pharmaceutical breakthroughs in recent years, showing great promise as diagnostic and therapeutic agents for malignant tumors, cardiovascular disease, diabetes, viral infections, and many other degenerative disorders.
Analyzing Longitudinal Clinical Trial Data: A Practical Guide provides practical and easy to implement approaches for bringing the latest theory on analysis of longitudinal clinical trial data into routine practice.
Addressing issues at the forefront of interest for the Clinical Trial Materials Professional (CTMP), this Second Edition highlights the most critical concepts related to the planning, manufacturing, packaging, labeling, distribution, reconciliation, and quality and regulatory control of clinical trial materials-offering an authoritative selection of chapters on the current and evolving state of clinical supplies operations by esteemed researchers and consultants in industry.
miRNAs are a class of endogenous, small non-protein coding RNA molecules (~ 22 nucleotides) which are novel post-transcriptional regulators of gene expression.
This book provides an in-depth description and discussion of different multi-modal diagnostic techniques for cancer detection and treatment using exact optical methods, their comparison, and combination.
This book provides a comprehensive description of sterols and their novel biological roles in mammalian signaling, the book covers their biosynthesis and structure, describes sterol receptor -mediated actions, their tissue distribution and their role in disease.
Theory of Drug Development presents a formal quantitative framework for understanding drug development that goes beyond simply describing the properties of the statistics in individual studies.
Stem cell therapy is ushering in a new era of medicine in which we will be able to repair human organs and tissue at their most fundamental level- that of the cell.
