Early detection of cancer at the cellular level, even before anatomic anomalies are visible, is critical to more efficacious and cost effective diagnosis and therapeutic advances.
For over forty years, mesenchymal stem cells (MSCs) have been scrutinized and studied, garnering much attention due to their broad therapeutic efficacy.
Despite the many milestones in cystic fibrosis (CF) research, progress towards curing the disease has been slow, and it is increasingly difficult to grasp and use the already wide and still growing range of diverse methods currently employed to study CF so as to understand it in its multidisciplinary nature.
The development and rapid implementation of molecular genotyping methods have re- lutionized the possibility for differentiation and classification of microorganisms at the subspecies level.
Molecular modeling has undergone a remarkable transformation in the last 20 years, as biomolecular simulation moves from the realm of specialists to the wider academic community.
Biomarkers are molecular indicators of a biological status and, as biochemical species, can be interrogated to evaluate disease status and therapeutic interventions.
During the past decade, remarkable progress has been made in the development of newer drugs to prevent and treat thromboembolic disorders, such as oral direct anti-Xa and anti-IIa antagonists, as well as oral antiplatelet ADP antagonists with rapid onset and offset.
The avian influenza (AI) virus, which is the type A influenza virus adapted to an avian host, has been an important pathogen for the poultry industry worldwide for many years.
Over the past decades, the pathogenesis, diagnosis, treatment and prevention of cardiovascular diseases have been benefited significantly from intensive research activities.
Clinical epidemiology provides the scientific basis for the practice of medicine due to its focus on the diagnosis, prognosis and management of human disease using appropriate research design, measurement and evaluation.
Since its early days in the 1990s, the Quorum Sensing (QS) field has grown from a few dozen laboratories, investigating the pathways, proteins, and chemicals that facilitate signaling in bacteria, to hundreds of groups that have integrated evolutionary biology, computer science, mathematics, engineering, and metagenomics to create an ever-expanding and dynamic field.
Due to the complexity of the mitochondrial system and the myriad genes involved in their function, the clinical manifestations of mitochondrial diseases are remarkably variable and heterogeneous.
Non-clinical drug safety evaluation, the assessment of the safety profile of therapeutic agents through the conduct of laboratory studies in in vitro systems and in animals, is an essential step in the progress of new pharmaceuticals heading toward the ultimate goal of clinical trials and, eventually, approval.
This book provides clinicians with the information needed to effectively interpret the literature from observational and interventional cardiovascular outcomes studies.
After 18 years since the first biosimilar was approved, a lot has changed, from the regulatory guidelines to the stakeholder perceptions about the safety and efficacy of biosimilars.
La Guia de practica clinica para prevencion, diagnostico y tratamiento de las lesiones precursoras del cancer de cuello uterino, es un instrumento confiable, que cuenta con la mas alta calidad metodologica, de consulta rapida, en el que podran encontrar informacion actualizada rigurosamente escogida y calificada para brindar contenido respaldado en la mejor evidencia disponible al momento.
'An essential guide' (Dr Mark Hyman, author of Young Forever) to navigating life with the cognitive and mental health impairments that often accompany Long Covid.
This book begins with an introduction of pragmatic cluster randomized trials (PCTs) and reviews various pragmatic issues that need to be addressed by statisticians at the design stage.
This book addresses the stabilization of vaccine powders by spray drying and provides an overview of the current state of the art on a laboratory and industrial scale.
ONE OF THE NEW YORKER'S BEST BOOKS OF 2023 SO FARCHOSEN BY FINANCIAL TIMES' READERS' FOR BEST BOOKS OF 2023A NEW YORK TIMES BOOKS EDITOR' S CHOICE"e;Has the makings of a classic.
Fluorescence is the most popular technique in chemical and biological sensing because of its ultimate sensitivity, high temporal and spatial resolution and versatility that enables imaging within the living cells.
This book highlights recent research investigating psychological and neural mechanisms contributing to dysfunctional cognition in people with schizophrenia.
Health care today is known to suffer from siloed and fragmented data, delayed clinical communications, and disparate workflow tools due to the lack of interoperability caused by vendor-locked health care systems, lack of trust among data holders, and security/privacy concerns regarding data sharing.
This second edition offers 88 chapters divided among three volumes providing the most comprehensive source of know-how in the wide-ranging field of Mitochondrial Medicine.
This book of the series on "e;Advances in Biochemistry in Health and Disease"e; includes state-of-the-art information on the status of renin-angiotensin system (RAS) in the form of 24 chapters.
In the twenty-first century Pharmacognosy was transformed into a molecular science building on classic botanical and modern chemical knowledge, leading to a better understanding of the complex molecular effect - structure relationships and interactions required for the development of new drugs based on biologically active plant substances.
This book explores techniques for exploring hydrogen sulfide (H2S) and its effects on the vascular system through numerous experimental animal models and vascular preparations.
The book provides a comprehensive overview of classic and modern approaches of centrosome research, including new aspects of centrosome functions focusing on primary cilia and their implications in numerous diseases.
The main aim of this book is to offer an easy tool to read a scientific article with greater awareness, to understand and evaluate it more thoroughly, and to better plan research.
The book Function-oriented bioengineered skin equivalents - continuous development towards complete skin replication aims to provide potential readers with a comprehensive summary of the available information on various in vitro skin models, from historical background to different modeling approaches and their applications.
This book entitled "e;Cancer Stem Cell Markers and Related Network Path-ways"e; is about cancer stem cell (CSC) markers and the molecular network pathways.
Brain tumors comprise about 5-9% of all human neoplasms; and interestingly the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well.
This book focuses on the challenges to biomedical education posed by the lockdowns and restrictions to on campus teaching brought about by the COVID-19 pandemic and highlights the tools and digital visualization technologies that have been successfully developed and used for remote teaching.
Hundreds of eponyms are used within the field of immunology-Petri dish, Crohn's disease, Bence Jones protein, Kupffer cells, Freund's adjuvant, Ouchterlony immunodiffusion, to name just a few-but most of us don't know much about the individuals who gave their names to these terms.