Acacias: The Genus Acacia (sensu lato) is an evidence-based treatment of this supergenus, through the eyes of a clinical pharmacognosist and integrative medicine specialist.
Symptoms of the breast in gravid women commonly represent physiological changes, however they may also be related to serious underlying breast disease; this challenging dilemma is aggravated by diagnostic and therapeutic limitations imposed by safety issues regarding the mother and fetus.
In addition to its metabolic and endocrinologic effects, obesity and adipose tissue have now been shown to be associated with low grade inflammation resulting in cellular and humoral inflammatory factors of which the latter may act by endocrine, paracrine and autocrine mechanisms.
This volume provides detailed protocols for the identification and understanding of vasculogenic mimicry process in vitro and in vivo, in addition to protocols for microscopy and histology.
Two decades after radiocarbon dating declared the Turin Shroud a mediaeval fake, brand-new historical discoveries strongly suggest that this famous cloth, with its extraordinary photographic imprint, is genuinely Christ's shroud after all.
Building upon the foundation of basics discussed in the previous edition, the Second Edition provides a more in-depth look at the latest methods and technologies of advanced drug screening, an essential function of drug discovery.
Examines Critical Decisions for Transitioning Lab Science to a Clinical SettingThe development of therapeutic pharmaceutical compounds is becoming more expensive, and the success rates for getting such treatments approved for marketing and to the patients is decreasing.
This comprehensive volume will serve as a complete guide to the clinical application of computer assisted systems in monitoring central nervous functions both in the OR and ICU.
Already popular in the analysis of medical device trials, adaptive Bayesian designs are increasingly being used in drug development for a wide variety of diseases and conditions, from Alzheimer's disease and multiple sclerosis to obesity, diabetes, hepatitis C, and HIV.
Chemical Induction of Cancer: Structural Bases and Biological Mechanisms, Volume IIIB: Aliphatic and Polyhalogenated Carcinogens covers environmentally and occupationally significant carcinogens of industrial origins.
Dynamic Treatment Regimes: Statistical Methods for Precision Medicine provides a comprehensive introduction to statistical methodology for the evaluation and discovery of dynamic treatment regimes from data.
This book provides an overview of the biology and biochemistry of peroxisomes, and discusses the contribution of these organelles to peroxisomal and neurodegenerative diseases.
A complete guide to the key statistical concepts essential for the design and construction of clinical trials As the newest major resource in the field of medical research, Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs presents a timely and authoritative reviewof the central statistical concepts used to build clinical trials that obtain the best results.
This fascinating volume delves into the forefront of pharmaceutical research to shed light on the ground-breaking methodologies and technologies driving advancements in drug discovery today.
This edited book contains chapters that describe bespoke three-dimensional (3D) printing aimed at democratizing anatomy education by providing open-source scans for download and printing as 3D models.
The Biology and Therapeutic Application of Mesenchymal Cells comprehensively describes the cellular and molecular biology of mesenchymal stem cells and mesenchymal stromal cells, describing their therapeutic potential in a wide variety of preclinical models of human diseases and their mechanism of action in these preclinical models.
Useful Statistical Approaches for Addressing Multiplicity IssuesIncludes practical examples from recent trials Bringing together leading statisticians, scientists, and clinicians from the pharmaceutical industry, academia, and regulatory agencies, Multiple Testing Problems in Pharmaceutical Statistics explores the rapidly growing area of multiple comparison research with an emphasis on pharmaceutical applications.
This book is based on a study of referees' reports and letters from journal editors on reasons why papers written by non-native researchers are rejected due to problems with English (long sentences, redundancy, poor structure etc).
Individual Participant Data Meta-Analysis: A Handbook for Healthcare Research provides a comprehensive introduction to the fundamental principles and methods that healthcare researchers need when considering, conducting or using individual participant data (IPD) meta-analysis projects.
The role of free radicals and oxidative stress in neurological disorders has only recently been recognized, leaving clinical neurologists to seek in vain for information on the subject even in major textbooks.
The central theme running through this volume on New Technologies for Toxicity Testing is the development and application of advanced techniques for cell and tissue culture, as well as new markers and endpoints of toxicity, as alternatives to the traditional paradigm of relying on data from laboratory animal tests to undertake labelling and risk assessment.
A unique, holistic approach covering all functions and phases of pharmaceutical research and development While there are a number of texts dedicated to individual aspects of pharmaceutical research and development, this unique contributed work takes a holistic and integrative approach to the use of computers in all phases of drug discovery, development, and marketing.
Homosexual Behavior: Therapy and Assessment explores the extent to which principles derived from the experimental psychology of learning could be applied to the treatment of a variety of behaviors.
A practical and methodological approach to the statistical logic of biostatistics in the field of health research Focusing on a basic understanding of the methods and analyses in health research, Introduction to Biostatistical Applications in Health Research with Microsoft Office Excel provides statistical concepts for interpreting results using Excel.
Immediate early genes (IEGs) are a class of genes that are rapidly expressed without new protein synthesis and, in most cases, in direct response to synaptic input.