Clinical Trial Optimization Using R explores a unified and broadly applicable framework for optimizing decision making and strategy selection in clinical development, through a series of examples and case studies.
This book highlights the recent advancement in point-of-care testing (POCT) technologies utilizing 'smart' nanomaterials for the analysis of biomarkers related to disease, which includes metabolites, enzymes, proteins, nucleic acids, cancer cells and multidrug-resistant pathogen.
Dermatopathology is a specialized branch of pathology in which there has been great progress as new techniques have become available to evaluate the pathology of the skin.
Synthetische Biologie ist ein neuer Wissenschaftszweig, der große Hoffnungen auf Fortschritte in der Medizin, in der Landwirtschaft und in den Energie-, Ernährungs- und Gesundheitswirtsschaftszweigen weckt.
Development of Anti-Asthma Drugs reviews existing asthma treatments and novel approaches currently under investigation, in the context of their mode of action and clinical effectiveness, in the hope that this might lead to a greater understanding of the factors involved in the expression of the disease and, therefore, in the design of better drugs.
This volume explores experimental approaches used to study Duchenne muscular dystrophy (DMD), an X-linked degenerative skeletal muscle disease caused by mutations in the dystrophin gene.
Cell Surface Receptors: A Short Course on Theory and Methods, 3rd Edition, links theoretical insights into drug-receptor interactions described in mathematical models with the experimental strategies to characterize the biological receptor of interest.
This volume is a unique compendium of professional and practical knowledge on new paradigms and approaches in Teaching, Research, Innovation and Public Engagement that is currently missing from the Higher Education market.
In response to the US FDA's Critical Path Initiative, innovative adaptive designs are being used more and more in clinical trials due to their flexibility and efficiency, especially during early phase development.
For two decades, Understanding Clinical Papers has been helping students and professionals understand the research that supports evidence-based practice.
This book examines the emergent and expanding role of technologies that hold both promise and possible peril for transforming the ageing process in this century.
This book shows how and why quality assurance programmes should be implemented in laboratory rodent facilities to monitor animal health and genetic status.
This completely updated and expanded 2nd Edition provides all the information needed in order to understand the complex molecular, cellular and genetic mechanisms that underlie normal and abnormal cardiac rhythms.
Hybrid Frequentist/Bayesian Power and Bayesian Power in Planning Clinical Trials provides a practical introduction to unconditional approaches to planning randomised clinical trials, particularly aimed at drug development in the pharmaceutical industry.
This book presents current understanding of the importance of modern immunology in the etiopathogenesis of human diseases and explores how this understanding is impacting on diagnosis, prognosis, treatment, and prophylaxis.
This book introduces you to the basic rules and principles of statistics and shows you how straightforward statistical tests can be performed and analysed in relation to healthcare.
This volume presents advanced bio/medical sciences with a particular value for translating research achievements into daily medical practice in the framework of Predictive, Preventive and Personalised Medicine (3PM/PPPM).