Medical research

This book focuses on associative memory cells and their working principles, which can be applied to associative memories and memory-relevant cognitions.

The world we live in is hugely unequal.

After reviewing the history of cancer and its impact on the population, Dr.

For a virus to invade a host cell it needs to penetrate the physical barrier imposed by the plasma membrane.

In the past decade, we have experienced an explosion of new information about cancer therapeutic targets.

This book addresses the background and significance of the factors potentially influencing the clinical and biological outcomes of metal-on-metal hip implants.

This book is a joint package of a practical manual on how to undertake meta-analysis in medicine together with an accompanying CD-ROM.

With the critical role of statistics in the design, conduct, analysis and reporting of clinical trials or observational studies intended for regulatory purposes, numerous guidelines have been issued by regulatory authorities around the world focusing on statistical issues related to drug development.

The pharmaceutical industry relies on numerous well-designed experiments involving high-throughput techniques and in silico approaches to analyze potential drug targets.

Despite remarkable progress in genome science, we are still far from a clear understanding of how genomic DNA is packaged without entanglement into a nucleus, how genes are wrapped up in chromatin, how chromatin structure is faithfully inherited from mother to daughter cells, and how the differential expression of genes is enabled in a given cell type.

This guide provides a framework, starting from simple statements, for writing papers for submission to peer-reviewed journals.

Mitochondrial diseases are often hard to diagnose.

Do statistics-heavy research papers give you a headache?

Myosins are molecular motors that use the energy from ATP hydrolysis to move and exert tension on actin filaments.

Molecular biology has rapidly advanced since the discovery of the basic flow of information in life, from DNA to RNA to proteins.

Biomaterials: From Molecules to Engineered Tissue gives examples of the application areas of biomaterials involving molecules at one end of the spectrum and finished devices in the other.

The cannabinoid system plays a central role in a wide variety of physiological functions that touch upon cardiovascular, gastrointestinal, immune, and nervous systems.

Clinical trials have revolutionized the way disease is prevented, detected and treated, and early death avoided, and they continue to be an expanding area of research.

Providing more than just a comprehensive history, critical vocabulary, insightful compilation of motivations, and clear explanation of the state-of-the-art of modern clinical trial simulation, this book supplies a rigorous framework for employing simulation as an experiment, according to a predefined simulation plan, that reflects good simulation p

A new edition of the classic guide to the use of statistics in medicine, featuring examples from articles in the New England Journal of Medicine Medical Uses of Statistics has served as one of the most influential works on the subject for physicians, physicians-in-training, and a myriad of healthcare experts who need a clear idea of the proper application of statistical techniques in clinical studies as well as the implications of their interpretation for clinical practice.

The Power of Rare is equal parts science and inspiration.

Plain English for Doctors shows how to write about medical science in a clear and vivid way.

What does it take to be a scientist?

The explanation and implementation of statistical methods for the medical researcher or statistician remains an integral part of modern medical research.

Myosins are molecular motors that use the energy from ATP hydrolysis to move and exert tension on actin filaments.

This edited volume aims to better understand the multifaceted phenomenon we call health.

This revised and updated new edition of a best-selling text remains a fast and convenient overview of the clinical trials in gynecologic cancer treatment, outlining the evidence base of treatment decisions in uterine, ovarian, cervical, and vulvar cancers, and gestational trophoblastic neoplasia.

The Physical Basis of Biochemistry: Solutions Manual to the Second Edition offers solutions to the problem sets from the second edition of The Physical Basis of Biochemistry.

Contemporary Neurology compiles a large series of papers on the commonest neurological problems.

This comprehensive volume compiles the concepts essential for the understanding of the pharmaceutical science and technology associated with the delivery of subunit vaccines.

It is now ten years since the first Handbook on Hyperbaric Medicine was published.

Clinical Immunobiology, Volume 3 covers a variety of methods used for assaying the immune status of an individual.

This book is a continuance of the topic: "e;DAMPs in Human Diseases"e;, the basics of which were described in a first volume by the same author.

Ischemic heart disease is the leading cause of morbidity and mortality in the developed world.

The aim of this unique volume is to help medical researchers design clinical trials to improve survival, remission duration, or time to recurrence of disease.

Examining how to maintain assured quality in clinical trial research, A Practical Guide to Quality Management in Clinical Trial Research provides solid foundations, tips, and techniques for establishing a quality system that will comply with the relevant regulations.

The definitive guide to CBPR concepts and practice, updated and expanded Community-Based Participatory Research for Health: Advancing Health and Social Equity provides a comprehensive reference for this rapidly growing field in participatory and community-engaged research.

This book focuses on the emerging role of ferroptosis in human diseases.

Interesting and important ethical questions confront researchers, regulators, institutional review boards, support personnel, and research participants committed to the ethical conduct of human subjects research at all stages of research.

Now viewed as its own scientific discipline, clinical trial methodology encompasses the methods required for the protection of participants in a clinical trial and the methods necessary to provide a valid inference about the objective of the trial.

Genetic Counseling Research: A Practical Guide is the first text devoted to research methodology in genetic counseling.

Cancer Clinical Trials: Current and Controversial Issues in Design and Analysis provides statisticians with an understanding of the critical challenges currently encountered in oncology trials.

That residues of pesticide and other "e;foreign"e; chemicals in foodstuffs are of concern to everyone everywhere is amply attested by the reception accorded previous volumes of "e;Residue Reviews"e; and by the gratifying en- thusiasm, sincerity, and efforts shown by all the individuals from whom manuscripts have been solicited.

This book reviews advances in understanding phosphodiesterases within the central nervous system and their therapeutic applications.

Written by internationally recognized leaders in Heparanase biology, the book's eight chapters offer an opportunity for scientists, clinicians and advanced students in cell biology, tumor biology and oncology to obtain a comprehensive understanding of Heparanase's multifaceted activities in cancer, inflammation, diabetes and other diseases, as well as its related clinical applications.

Biopharmaceuticals, the term for genetically engineered therapeutic proteins, monoclonal antibodies, and nucleic acid-based products, have become an increasing part of the pharmaceutical armament.

Metastasis (spread of cancer in the body) is the main cause of death for patients with breast cancer, the leading female tumour in the industrialised countries and developing countries alike.

Being that pharmacokinetics (PK) is the study of how the body handles various substances, it is not surprising that PK plays an important role in the early development of new drugs.