Medical research

Malignant effusions (pleurites, ascites and pericarditis) are some of the most frequent manifestations of dissemination process of malignant tumors.

A concise description of models and quantitative parameters in structural chemistry and their interrelations, with 280 tables and >3000 references giving the most up-to-date experimental data on energy characteristics of atoms, molecules and crystals (ionisation potentials, electron affinities, bond energies, heats of phase transitions, band and lattice energies), optical properties (refractive index, polarisability), spectroscopic characteristics and geometrical parameters (bond distances and angles, coordination numbers) of substances in gaseous, liquid and solid states, in glasses and melts, for various thermodynamic conditions.

Main Question: G protein coupled receptors are involved in highly efficient and specific activation of signalling pathways.

Since the beginning of the 21st Century there has been a rapid increase in our understanding of the cellular trafficking mechanisms of molecular chaperones in eukaryotes and in prokaryotes.

Glioma Signaling is a text reference on cellular signaling processes focused on the mechanism of nucleotide receptors activation by exogenic nucleotides and the formation of complex signaling cascades, including cytoplasmic transcription factors, induced by growth factors, cytokines and cannabinoids.

The book represents a comprehensive review and synthesis of the biomedical literature that spans over a half-century on a single protein called glyceraldehyde 3-phosphate dehydrogenase (or, GAPDH).

The growing knowledge on tumor-immune response interactions and on the tumor microenvironment did not translate so far into better control of cancer by anti-tumor vaccination.

This Brief provides a concise review of chaperonopathies, i.

The field of microRNA biology is really emerging in the last couple of years.

Timing, racing, combating, struggling and targeting are some actions through which cellular fate could be reflected and evaluated.

In healthcare, the realisation of an optimistic prognosis against pessimistic ones depends on current innovations in diagnostic and cost-effective treatment approaches being widely adopted in clinical practice.

G protein coupled receptors (GPCRs) comprise an important protein family, which is involved in signal transduction in the cell.

The existence of 'cancer stem cells' (CSCs) has been a topic of heated debate for the last few years within the field of cancer biology.

Arterial chemoreceptors are unique structures which continuously monitor changes in arterial blood oxygen, carbon dioxide, glucose, and acid.

Angiogenesis and lymphangiogenesis have become attractive targets for drug therapy because of their key roles in a broad spectrum of pathological disease states ranging from macular degeneration to tumor growth and metastasis.

Cancer still remains a most important killer and even though synthetic chemotherapeutic agents are currently used, they are cost-intensive and do not always meet the expectations.

High-fidelity chromosomal DNA replication underpins all life on the planet.

This book, an international collaborative effort in the area of molecular respiratory research, showcases a broad range of multidisciplinary approaches to unravel and analyze the underlying mechanisms of a spectrum of respiratory ailments.

This book, written for pulmonary and family doctors, general practitioners, allergologists, and neuropsychologists, presents cutting-edge clinical research and therapy-oriented knowledge in the field of respiratory medicine.

Prevention of infectious diseases by vaccination is one of the most significant achievements of modern medicine.

Having last year published "e;Up from Clinical Epidemiology & EBM"e; and also "e;Epidemiological Research: Terms and Concepts,"e; Miettinen now - this time with collaboration from his junior colleague I.

Physical implementation of the memristor at industrial scale sparked the interest from various disciplines, ranging from physics, nanotechnology, electrical engineering, neuroscience, to intelligent robotics.

The Endoplasmic Reticulum (ER) is an organelle with extraordinary signaling and homeostatic functions.

The rapidly developing field of systems biology is influencing many aspects of biological research and is expected to transform biomedicine.

Coxiella burnetii is the etiological agent of Q fever, a zoonotic disease found worldwide.

This book is about Nutraceuticals in cancer therapy, specifically targeted and Adjuvant therapy.

The first of its kind, this book describes pediatric palliative care in more than 23 countries.

This book attempts to set communicable diseases and the efforts to control them in a social and historical context.

Recent technological breakthrough in the field of Terahertz radiation has triggered new applications in biology and biomedicine.

Humans have utilized the bioactive principles of different plants for various beneficial physiological properties including antimicrobial properties for many centuries.

Inflammatory breast cancer is the most deadly subtype of breast cancer because it can spread to other organs despite of multidisciplinary approach.

The phrase "e;Life, stress and death"e; connects three terms, but is there a biological basis for that?

Routine applications of advanced statistical methods on real data have become possible in the last ten years because desktop computers have become much more powerful and cheaper.

Phosphoinositides play a major role in cellular signaling and membrane organization.

Phosphoinositides play a major role in cellular signaling and membrane organization.

Chemoprevention of cancer has been the focus of intensive research for more than two decades.

This atlas will illustrate the distribution and morphological features of interstitial cells of Cajal (ICC) which are the key cells to understanding of the regulatory mechanism of gastrointestinal motility, since ICC act as both pacemaker and as intermediates in neural transmission, and since ICC show specific distribution patterns depending on their anatomical positions.

It is pointed out that a cancer stem cell is a type within a tumor that possesses the capacity of self-renewal and can give rise to the heterogeneous lineages of cancer cells, which comprise the tumor.

Various aspects, including diagnosis, therapy, and prognosis, of two brain tumors (meningioma and schwannoma) , of brain tumors are discussed in this volume.

Mitochondria are far more than the "e;powerhouse"e; of the cell as they have classically been described.

This volume contains information on the diagnosis, therapy, and prognosis of spinal tumors.

Thanks to the omnipresent computer, current statistics can include data files of many thousands of values, and can perform any exploratory analysis in less than seconds.

The US is currently well ahead of the rest of the world in the development and application of SB and its principles especially as they pertain to basic medical research and development.

Vast therapeutic applications of the following specific stem cells in disease and tissue injury are discussed: embryonic stem cells, induced pluripotent stem cells, human hair follicle stem cells, bone marrow-derived human mesenchymal stem cells, adipose-derived stem cells, periodontal/progenitor cells, cancer stem cells, and breast cancer stem cells.

This book fills in a gap in the NO literature.

The main objective of this book is to provide a comprehensive review on stem cells and their role in tissue regeneration, homeostasis and therapy.

This volume brings together a range of interdisciplinary perspectives on a topic of central importance, but which has otherwise tended to be approached from within just one or another disciplinary framework.

Amyloid-forming proteins are implicated in over 30 human diseases.

Although modern medicine enjoys unprecedented success in providing excellent technical care, many patients are dissatisfied with the poor quality of care or the unprofessional manner in which physicians sometimes deliver it.

This book is the first major work that addresses a core question in biomedical research: the question of acceptable risk.