A balanced treatment of the theories, methodologies, and design issues involved in clinical trials using statistical methods There has been enormous interest and development in Bayesian adaptive designs, especially for early phases of clinical trials.
This first-of-its-kind book for underrepresented racial and ethnic minorities (URM), women, and sexual and gender minorities in medicine offers the core knowledge and skills needed to achieve a well-planned, fulfilling career in academic medicine.
This book will describe current research on drug delivery systems that encompass four broad categories, namely: routes of delivery, delivery vehicles, payload, and targeting strategies.
Advances in Cognitive-Behavioral Research and Therapy, Volume 2 provides information pertinent to the fundamental aspects of cognitive-behavioral approaches to psychotherapy.
Membrane Proteins - Production and Function Characterization a volume of Methods in Enzymology, encompasses chapters from the leading experts in the area of membrane protein biology.
The third edition of this best-selling book continues to offer a user-friendly, step-by-step introduction to all the key processes involved in bringing a drug to the market, including the performance of pre-clinical studies, the conduct of human clinical trials, regulatory controls, and even the manufacturing processes for pharmaceutical products.
This text traces developments in rational drug discovery and combinatorial library design with contributions from 50 leading scientists in academia and industry who offer coverage of basic principles, design strategies, methodologies, software tools and algorithms, and applications.
Electricity and Magnetism (E&M) underlies many lifesaving medical devices, such as magnetic resonance imaging scanners, neural stimulators, and heart pacemakers.
More than 150 patient cases teach you how to apply the principles of pharmacotherapy to real-world clinical practiceThe essential study companion to DiPiro s Pharmacotherapy: A Pathophysiologic Approach, 10th EditionPharmacotherapy Casebook: A Patient-Focused Approach uses 157 patient cases to help you develop the skills necessary to identify and resolve the most common drug therapy problems encountered in daily clinical practice.
Aphasia, Volume 185 covers important advances in our understanding of how language is processed in the brain and how lesions or degeneration in the left hemisphere affect language processing.
This book contextualizes translational research and provides an up to date progress report on therapies that are currently being targeted in lung cancer.
This reference presents a detailed overview of approaches and techniques in the management of pain caused by tissue, nerve and central nervous system injuries, categorizing pain into a variety of syndromes and underlying mechanisms to aid the development of interventional pharmacologic measures.
The transformative role of artificial intelligence (AI) in modern biomanufacturing focuses on key areas such as process analytical technology (PAT), Good Manufacturing Practice (GMP) compliance, predictive analytics, and AI-driven quality systems.
Examines Critical Decisions for Transitioning Lab Science to a Clinical SettingThe development of therapeutic pharmaceutical compounds is becoming more expensive, and the success rates for getting such treatments approved for marketing and to the patients is decreasing.
A page-turning and powerful medical mystery for readers of Diagnosis by Lisa Sanders and The Beauty in Breaking by Michele HarperMore than 20 million Americans have autoimmune diseases, which occur when the immune system attacks the body.
Green fluorescent proteins have been floating in the ocean for more than 160 million years, but it took a curious scientist, fascinated by pinpricks of green light, to begin unlocking their potential.
This book focuses on novel approaches that provide a reliable basis for identifying what kinds of patients are likely to benefit from the each new treatment.
This book brings together the voices of leading experts in the frontiers of biostatistics, biomedicine, and the health sciences to discuss the statistical procedures, useful methods, and novel applications in biostatistics research.
The acclaimed textbook for navigating the practice and challenges of public health, now updated and completely revised "e;It should be recommended or assigned to all students in public health.
The advancement of science is ever more contingent upon the interaction of experts vast amount of scientific information being gathered every day that exceeds the ability of any one scientist to acquire.
A Single Source on Parallel Synthesis for Lead OptimizationThe end of the previous millennium saw an explosion in the application of parallel synthesis techniques for making compounds for high-throughput screening.
This text book will bring together a mix of both internationally known and established senior scientists along side up and coming (but already accomplished) junior scientists that have varying expertise in fundamental and applied nanotechnology to biology and medicine.
Drugs in Society: Causes, Concepts, and Control, Eighth Edition, focuses on the many critical areas of America's drug problem, providing a foundation for rational decision-making within this complex and multidisciplinary field.
Community-based participatory research (CBPR) emerged in response to the longstanding tradition of "e;top-down"e; research-studies in which social scientists observe social phenomena and community problems as outsiders, separate from the participants' daily lives.
Reflecting the shift from genetics to genomics in the pharmaceutical sphere, this Second Edition traces the evolution of the science of pharmacogenetics and gathers research from the forefront of the field-spanning the most influential breakthroughs in molecular diagnostics, metabonomics, proteomics, bioinformatics, disease mapping, pharmacodynamic
That residues of pesticide and other "e;foreign"e; chemicals in foodstuffs are of concern to everyone everywhere is amply attested by the reception accorded previous volumes of "e;Residue Reviews"e; and by the gratifying en- thusiasm, sincerity, and efforts shown by all the individuals from whom manuscripts have been solicited.
Get Up to Speed on Many Types of Adaptive DesignsSince the publication of the first edition, there have been remarkable advances in the methodology and application of adaptive trials.
The object of "e;Residue Reviews"e; is to provide concise, critical reviews of timely advances, philosophy, and significant areas of accomplished or needed endeavor in the total field of residues of pesticide and certain other chemicals in foods, feeds, and in transformed food products.
With this valuable practical guide, three members of the Harvard Stem Cell Institute have compiled and edited the definite handbook for the exciting new field of human embryonic stem cell research.
In recent years, many pharmaceutical companies and clinical research organizations have been focusing on the development of traditional Chinese (herbal) medicines (TCMs) as alternatives to treating critical or life-threatening diseases and as pathways to personalized medicine.
