Statistical methods that are commonly used in the review and approval process of regulatory submissions are usually referred to as statistics in regulatory science or regulatory statistics.
Handbook for Clinical Trials of Imaging and Image-Guided Interventions is the first single-source, multi-disciplinary reference, based on the didactic sessions presented at the annual Clinical Trials Methodology Workshop for radiologists, radiation oncologists and imaging scientists (sponsored by the Radiological Society of North America (RSNA)).
Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials.
Aggregates of the TAR DNA binding protein 43 (TDP-43), are hallmark features of the neurodegenerative diseases Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD), with overlapping clinical, genetic and pathological features.
Focusing on group sequential procedures, summarizes the sequential statistical methods used in anticancer, antiviral, cardiovascular, and gastrointestinal drug research and screening.
Highly recommended by CHOICE, Oct 2018Extremophiles are nature's ultimate survivors, thriving in environments ranging from the frozen Antarctic to abyssal hot hydrothermal vents.
This reference book equips readers with cutting-edge information on the many advances in diagnostic and therapeutic treatments for human diseases that have been made in recent years, with examples from laboratory medicine.
When the woman he loved was diagnosed with a metastatic cancer, science-writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it.
Despite the phenomenal clinical success of antibody-based biopharmaceuticals in recent years, discovery and development of these novel biomedicines remains a costly, time-consuming, and risky endeavor with low probability of success.
Proceedings of the Light-Activated Tissue Regeneration and Therapy Conference covers issues such as the latest advances in the field and measurements including the determination of the mechanisms of light-activated tissue regeneration and therapy.
That residues of pesticide and other "e;foreign"e; chemicals in foodstuffs are of concern to everyone everywhere is amply attested by the reception accorded previous volumes of "e;Residue Reviews"e; and by the gratifying en- thusiasm, sincerity, and efforts shown by all the individuals from whom manuscripts have been solicited.
The interdisciplinary field of molecular systems biology aims to understand the behavior and mechanisms of biological processes composed of individual molecular components.
The definitive guide to CBPR concepts and practice, updated and expanded Community-Based Participatory Research for Health: Advancing Health and Social Equity provides a comprehensive reference for this rapidly growing field in participatory and community-engaged research.
This edition includes both updates and new uses and issues concerning CTS, along with case studies of how clinical trial simulations are being applied in various therapeutic and application areas.
That residues of pesticides and other "e;foreign"e; chemicals in foodsttrlfs are of concern to everyone everywhere is attested by the reception accorded earlier volumes of "e;Residue Reviews"e;, and by the gratifying enthusiasm, sincerity, and efforts shown by the individuals I have asked to prepare manuscripts.
Medicinal Plants in the Asia Pacific for Zoonotic Pandemics provides an unprecedented, comprehensive overview of the phylogeny, botany, ethnopharmacology, and pharmacology of more than 100 plants used in the traditional systems of Asia and Pacific medicine for the treatment of microbial infections.
Nearly 97% of the human genome is the non-coding DNA, which varies from one species to another, and changes in these sequences are frequently noticed to manifest clinical and circumstantial malfunction.
For more than five decades, scientists and researchers have relied on the Advances in Chromatography series for the most up-to-date information on a wide range of developments in chromatographic methods and applications.
Adaptive Designs for Sequential Treatment Allocation presents a rigorous theoretical treatment of the results and mathematical foundation of adaptive design theory.
That residues of pesticide and other "e;foreign"e; chemicals in foodstuffs are of concern to everyone everywhere is amply attested by the reception accorded previous volumes of "e;Residue Reviews"e; and by the gratifying enthusiasm, sincerity, and efforts shown by all the individuals from whom manuscripts have been solicited.
Neurofeedback: Functions, Applications and Effects presents a number of possible applications for neurofeedback in offender treatment, including perpetuators of domestic violence and various other forms of violent and anti-social behavior, certain forms of sexually abusive behavior, and criminal behavior of an obsessive-compulsive nature.
In anaesthetist Dr Kevin Fong's television programmes he has often demonstrated the impact of extremes on the human body by using his own body as a 'guinea pig'.
A True Insider's Guide to the Field - Then and Now Until now, there has not been a book that effectively addresses the historical basis of protein discovery.
La médecine progresse chaque jour, mais il n’est pas toujours évident pour nous, simples patients, de comprendre les applications de nouvelles découvertes.
This book gives professionals in clinical research valuable information on the challenging issues of the design, execution, and management of clinical trials, and how to resolve these issues effectively.
Recent Advancement in ProdrugsDrugs used as medicines have many limitations like low chemical stability, aqueous solubility, or oral absorption/bioavailability, rapid presystemic metabolism, toxicity, inadequate site specificity, or poor patient acceptance/compliance (unwanted adverse effects, unacceptable taste or odor, irritation or pain).
Methods of Animal Experimentation, Volume V: Nutrition, Aging, and Artificial Organs is a collection of papers that deals with methods to be used in animal experiments to achieve cost effectiveness in their use.
Guides readers on the proper use of in vitro drug release methodologies in order to evaluate the performance of special dosage forms In the last decade, the application of drug release testing has widened to a variety of novel/special dosage forms.
Forkhead Transcription Factors: Vital Elements in Biology and Medicine provides a unique platform for the presentation of novel work and new insights into the vital role that forkhead transcription factors play in multiple systems throughout the body.
The discovery of stress-induced mutagenesis has changed ideas about mutation and evolution, and revealed mutagenic programs that differ from standard spontaneous mutagenesis in rapidly proliferating cells.
