The practice of medicine is both learned and advanced through the compilation and study of cases -- vignettes that record the presentation, diagnosis, and treatment of individual patients and diseases.
After 18 years since the first biosimilar was approved, a lot has changed, from the regulatory guidelines to the stakeholder perceptions about the safety and efficacy of biosimilars.
Examines Critical Decisions for Transitioning Lab Science to a Clinical SettingThe development of therapeutic pharmaceutical compounds is becoming more expensive, and the success rates for getting such treatments approved for marketing and to the patients is decreasing.
Now viewed as its own scientific discipline, clinical trial methodology encompasses the methods required for the protection of participants in a clinical trial and the methods necessary to provide a valid inference about the objective of the trial.
The US Food and Drug Administration's Report to the Nation in 2004 and 2005 indicated that one of the top reasons for drug recall was that stability data did not support existing expiration dates.
Useful Statistical Approaches for Addressing Multiplicity IssuesIncludes practical examples from recent trials Bringing together leading statisticians, scientists, and clinicians from the pharmaceutical industry, academia, and regulatory agencies, Multiple Testing Problems in Pharmaceutical Statistics explores the rapidly growing area of multiple comparison research with an emphasis on pharmaceutical applications.
The increased use of non-inferiority analysis has been accompanied by a proliferation of research on the design and analysis of non-inferiority studies.
Bayesian analyses have made important inroads in modern clinical research due, in part, to the incorporation of the traditional tools of noninformative priors as well as the modern innovations of adaptive randomization and predictive power.
Randomised Response-Adaptive Designs in Clinical Trials presents methods for the randomised allocation of treatments to patients in sequential clinical trials.
Pharmacy Research: A How-To Guide for Students, Residents, and New Practitioners provides an introduction to research methods and a foundation on which individual research practices can be built.
With the prevalence of viral diseases causing significant health challenges and the emergence of highly infectious and difficult-to-treat conditions, such as Ebola, HIV/AIDS, and Hepatitis B, there is a pressing need for effective antiviral treatments.
An Introduction to Antibacterial Properties provides an overview of the current antibacterial techniques and main strategies being employed for controlling the colonisation of bacteria on surfaces, together with the design of antibacterial surfaces and their fabrication techniques.
Dysbiosis: A Study of Underlying Causes includes studies aimed at determining design interventions in which the composition of microbiota may be modulated to achieve a specific microbial profile beneficial to overall host behavior.
Over past several decades, an increasing number of cases of diverticulitis of colon have been reported making it a major health problem particularly in western countries.
Centuries ago, predicting was an enterprise entrusted to magic and fortune tellers, while today it is the domain of knowledge to which researchers and scientists contribute daily, analyzing and interpreting pathologies, trying to decode the complexity of life, represented by unresolved problems.
Instead of relying on prescription medications with numerous dangerous side effects, what if you could opt for a safer, natural alternative to address your health concerns?
The presented book is an easy-to-read and understandable text for experts in the medical field that are not familiar with the inorganic zeolite materials.
Oxidative Stress and Antioxidant Defense: Biomedical Value in Health and Diseases represent current findings on the impact of oxidative stress in the pathogenesis of diseases and underlying mechanisms of antioxidants influencing health and disease processes.
An Essential Guide to Astaxanthin: Dietary Sources, Properties and Health Benefits begins with a review of published studies regarding the efficacy and application of natural astaxanthin in aquaculture and human health, respectively.
This book attempts to address and answer questions about different types of disorders in particular developmental spheres in children with learning and behavioral problems.
This reference book equips readers with cutting-edge information on the many advances in diagnostic and therapeutic treatments for human diseases that have been made in recent years, with examples from laboratory medicine.
In the opening chapter, authors discuss the current literature that describes the application of Palliative Medicine services in advanced cancer, models of Palliative Care delivery by site and mode of practice, cost-effectiveness of early Palliative Medicine referral patterns and national and international Palliative Medicine practice and referral guidelines.
Neurofeedback: Functions, Applications and Effects presents a number of possible applications for neurofeedback in offender treatment, including perpetuators of domestic violence and various other forms of violent and anti-social behavior, certain forms of sexually abusive behavior, and criminal behavior of an obsessive-compulsive nature.
The book entitled "e;Lactate Dehydrogenase (LDH): Biochemistry, Functions and Clinical Significance"e; provides a broad and authoritative review of the lactate dehydrogenase enzyme, including its isoforms, catalytic functions, distribution in various tissues, involvement in cancer cell metabolism and tumorigenesis, involvement in the plasmodium enzyme, various small molecule inhibitors of hLDHA and pfLDH, and clinical significance.
This book presents, in two parts, a review concerning the use of Rattus norvegicus as a model for the study of neurological disorders and oncological diseases (mammary cancer).
