Already popular in the analysis of medical device trials, adaptive Bayesian designs are increasingly being used in drug development for a wide variety of diseases and conditions, from Alzheimer's disease and multiple sclerosis to obesity, diabetes, hepatitis C, and HIV.
From disease marker identification to accelerated drug development, Protein Arrays, Biochips, and Proteomics offers a detailed overview of current and emerging trends in the field of array-based proteomics.
Antimicrobial resistance (AMR) is increasing globally at an incredible rate, and many infectious diseases have already reached an alarming stage of resistance to existing treatments.
Researchers in structural genomics continue to search for biochemical and cellular functions of proteins as well as the ways in which proteins assemble into functional pathways and networks using either experimental or computational approaches.
This book describes the state of the art methods and applications for de novo design of drug candidates using generative chemistry models as well as the ethical aspects of this technology.
El descubrimiento de los rayos X posibilita la obtención de imágenes con fines de diagnóstico; sin embargo, por tratarse de radiaciones ionizantes el beneficio puede ir de la mano de un detrimento en la salud del paciente y del personal encargado de administrarlos, lo que exige implementar mecanismos para reducir la dosis de radiación, manteniendo la calidad de la imagen y limitar los riesgos para los trabajadores ocupacionalmente expuestos y el público que visita la instalación.
Helping you become a creative, logical thinker and skillful "e;simulator,"e; Monte Carlo Simulation for the Pharmaceutical Industry: Concepts, Algorithms, and Case Studies provides broad coverage of the entire drug development process, from drug discovery to preclinical and clinical trial aspects to commercialization.
El libro proporciona las bases científicas y las aplicaciones de los diseños de investigación que se pueden emplear en el estudio de las enfermedades bucales, así como la planificación, la ejecución y el análisis de resultados de los trabajos de investigación.
The microfluidic lab-on-a-chip allows scientists to conduct chemical and biochemical analysis in a miniaturized format so small that properties and effects are successfully enhanced, and processes seamlessly integrated.
Obesity is a global pandemic rising beyond the status of a lifestyle disorder, and its consequences include impaired metabolism, energy disruption, and abdominal fat deposition and storage.
Optimize Your Chemical DatabaseDesign and Use of Relational Databases in Chemistry helps programmers and users improve their ability to search and manipulate chemical structures and information, especially when using chemical database "e;cartridges"e;.
There is an increased awareness on the relevance of nutraceutical and functional foods as alternatives to harmful synthetic additives used in industry.
Bayesian Missing Data Problems: EM, Data Augmentation and Noniterative Computation presents solutions to missing data problems through explicit or noniterative sampling calculation of Bayesian posteriors.
This detailed volume collects diverse experimental approaches essential for researchers exploring the intricacies of cardiomyocyte biology and pathology.