In addition to its central role in blood coagulation, it has become increasingly apparent that thrombin and thrombin receptors are involved in many other physiological processes and can contribute to a variety of disease states such as tumor progression and metastasis, inflammation, neurological disorders and cardiovascular complications.
This book emphasizes the occurrence of sublethal injury in the indicator and pathogenic bacteria commonly encountered in foods, water and feed and modifications of the currently recommended methods for the effective detection of these bacteria.
This volume is a summary of material presented in the course given in the International School of Phannacology on "e;Drug Epidemiology and Post-Marketing Surveillance"e; between September 27 and October 8, 1990, at the "e;Ettore Majorana Center for Scientific Culture"e; in Erice, Sicily.
Geographers have for a long time contributed much valuable detailed data on the geographical patterns of disease and health care delivery to the medical world.
Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials gives a thorough presentation of state-of-the-art methods for early phase clinical trials.
Over the past two decades, the epidemic of HIV/AIDS has challenged the public health community to fundamentally rethink the framework for preventing infectious diseases.
This book focuses on analytical similarity assessment in biosimilar product development following the FDA's recommended stepwise approach for obtaining totality-of-the-evidence for approval of biosimilar products.
Artificial Intelligence Technology in Healthcare: Security and Privacy Issues focuses on current issues with patients' privacy and data security including data breaches in healthcare organizations, unauthorized access to patients' information, and medical identity theft.
Among the various theories proposed to account for the process of aging, the free radical theory is of practical interest since it includes the possibility of retarding this process by administrating natural or synthetic antioxidants and free radical scavengers.
This updated second edition of Molecular Typing in Bacterial Infections, presented in two volumes, covers both common and neglected bacterial pathogenic agents, highlighting the most effective methods for their identification and classification in the light of their specific epidemiology.
Hospitals monitoring is becoming more complex and is increasing both because staff want their data analysed and because of increasing mandated surveillance.
"e;The OHE Compendium of Health Statistics"e; is the one-stop statistical source specially designed for easy use by anyone interested in the UK health care sector and the NHS.
This book presents the methodology and applications of a range of important topics in statistics, and is designed for graduate students in Statistics and Biostatistics and for medical researchers.
Like its two successful previous editions, Health & Numbers: A Problems-Based Introduction to Biostatistics, Third Edition, is the only fully problems-based introduction to biostatistics and offers a concise introduction to basic statistical concepts and reasoning at a level suitable for a broad spectrum of students and professionals in medicine and the allied health fields.
This is a concise introduction to epidemiology and biostatistics written specifically for medical students and first-time learners of clinical research methods.
Simulating the behavior of a human heart, predicting tomorrow's weather, optimizing the aerodynamics of a sailboat, finding the ideal cooking time for a hamburger: to solve these problems, cardiologists, meteorologists, sportsmen, and engineers can count on math help.
All the Essentials to Start Using Adaptive Designs in No TimeCompared to traditional clinical trial designs, adaptive designs often lead to increased success rates in drug development at reduced costs and time.
Essential reading for social and medical scientists and all those interested in infectious diseases and public health, AIDS and the Twenty-First Century examines the social and economic origins and impacts of the HIV/AIDS epidemic.
This book shares the experimental findings and views in current multidisciplinary medical science combining both basic and applied research aimed at resolving problematic health issues.
The book examines the role of artificial intelligence during the COVID-19 pandemic, including its application in i) early warnings and alerts, ii) tracking and prediction, iii) data dashboards, iv) diagnosis and prognosis, v) treatments, and cures, and vi) social control.
Advanced Statistics in Regulatory Critical Clinical Initiatives is focused on the critical clinical initiatives introduced by the 21st Century Cure Act passed by the United States Congress in December 2016.
The previous edition of this useful text on epidemiologic methods for studying injuries and evaluating interventions to prevent them provides specific objectives for research in the various stages of injury control planning and implementation, including the types of data needed to reach the objectives.
Bayesian Approaches in Oncology Using R and OpenBUGS serves two audiences: those who are familiar with the theory and applications of bayesian approach and wish to learn or enhance their skills in R and OpenBUGS, and those who are enrolled in R and OpenBUGS-based course for bayesian approach implementation.
Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.
Progress in Molecular Biology and Translational Science provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology and translational science.
The book illustrates how biostatistics may numerically summarize human genetic epidemiology using R, and may be used successfully to solveproblems in quantitative Genetic Epidemiology Biostatistics for Human Genetic Epidemiology provides statistical methodologies and R recipes for human genetic epidemiologic problems.
Now in its second edition, this book brings multivariate statistics to graduate-level practitioners, making these analytical methods accessible without lengthy mathematical derivations.
"e;I recommend that all members of the health community read this book to obtain a real snapshot of how the Intelligent Health System is being transformed via new technologies.
An introduction to state-of-the-art modeling and simulation approaches for social and economic determinants of population health New Horizons in Modeling and Simulation for Social Epidemiology and Public Health offers a comprehensive introduction to modeling and simulation that addresses the many complex research questions in social epidemiology and public health.
This text is intended for those who wish to understand the complex relationships between diet and risks of important diseases, such as cancer and cardiovascular disease.
AN ESSENTIAL NEW RESOURCE ON A FUNDAMENTAL DETERMINANT OF HEALTHSleep, along with the sleep-related behaviors that impact sleep quality, have emerged as significant determinants of health and well-being across populations.