Thedevelopmentoftechnologiesforhigh-throughputmeasurementofgene expression in biological system is providing powerful new tools for inv- tigating the transcriptome on a genomic scale, and across diverse biol- ical systems and experimental designs.
During the last 50 years, the perception oftransposable elements (TEs) has changed considerably from selfish DNA to sequences that may contribute significantly to genome function and evolution.
This volume presents techniques needed for the study of long non-coding RNAs (lncRNAs) in cancer from their identification to functional characterization.
This fourth edition of the best-selling textbook, Human Genetics and Genomics, clearly explains the key principles needed by medical and health sciences students, from the basis of molecular genetics, to clinical applications used in the treatment of both rare and common conditions.
This is the first book specializing in plasmids and their biomedical use, including all relevant aspects of production, applications, quality, and regulations.
This is the first book to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of non-coding RNAs found to be associated with colorectal cancer pathogenesis.
This volume comprises the investigation of factors that may predict the response to treatment, outcome, and survival by exploring: design considerations in molecular epidemiology, including:case-onlyfamily-basedapproaches for evaluation of genetic susceptibility to exposure and addiction pharmacogeneticsincorporation of biomarkers in clinical tria
This book reports the recent progress in gene and cell therapy through the liver and aims to facilitate a comprehensive understanding of the current aspects and future prospects from basic research to clinical therapies.
Strategies or decisions aimed at affecting, in a manner considered to be positive, the genetic heritage of a child in the context of human reproduction are increasingly being accepted in contemporary society.
Many health care providers do not have either the knowledge or the tools they need in order to apply genetic information in their day-to-day practices.
If God can be used by the powerful to justify violence in the name of order, he can also be used by the weak to illuminate the position of the victims of political conflict.
Through analyses of the complex underlying issues, this interdisciplinary volume frames the agenda for dealing with genetic variation and incorporating pharmacogenomics into health care.
Inherited Metabolic Diseases are common enough for health, social service and education professionals to encounter them periodically, but rare enough for them to be poorly understood.
The way a cell undergoes malignant transformation should meet their capacity of surviving in the microenvironment of the organ where the cancer will develop.
This volume provides a comprehensive overview on developmental origins of health and disease regarding various factors related to the origins of non-communicable diseases (NCDs) from early life.
This highly informative and clearly written book presents the basic science and the latest data on hereditary breast and ovarian cancer (HBOC) to provide an up-to-date and holistic overview of the disease.
Highly valued across the world by genetic counsellors, medical geneticists and other healthcare professionals, Harper's Practical Genetic Counselling has established itself over previous editions as the essential guide to counselling those at risk from inherited disorders.
This third edition provides in-depth knowledge on the delivery of naked DNA and small-interfering RNA (siRNA) to the targeted microorganism, mammalian single cells, tissues, and animals for prevention and treatment of disease.
In genetics laboratories in Latin America, scientists have been mapping the genomes of local populations, seeking to locate the genetic basis of complex diseases and to trace population histories.
Lung ventilation is driven by a complex neural regulatory network, and apart from conditions typically observed during a disease state, it is sensitive to functional dysregulation.
This volume brings together recent developments in quasispecies theory extended to variable environments and practical applications in elucidating viral dynamics and treatment designs.
HELPS YOU DEVELOP AND ASSESS PEDIGREES TO MAKE DIAGNOSES, EVALUATE RISK, AND COUNSEL PATIENTS The Second Edition of The Practical Guide to the Genetic Family History not only shows how to take a medical-family history and record a pedigree, but also explains why each bit of information gathered is important.
This book will help readers navigate the complexity of mitochondrial disorders, by addressing the role of mitochondrial dysfunction and the complex pathophysiological mechanisms associated with a growing number of illnesses, not only of neurological interest.
The third edition of Craniofacial Embryogenetics and Development is dedicated to increased understanding of normal and abnormal orofacial development by integrating embryological development with its underlying genetic information.
Personalized nutrition involves the formulation of individualized nutritional recommendations to promote and maintain health based on an individual's genetic makeup and other unique intrinsic and extrinsic factors.
Members of the family Littorinidae are among the most widely studied gastropod molluscs and the more questions we answer about this group, the more questions are inevitably posed.
This manual covers all possible aspects of managing a child with differences in sex development, an entity easily missed by the unsuspecting clinician.
Precision pathology of cancer is a new frontier - a systemic diagnostic approach to provide specific therapeutic targets and genetic and metabolic information for the treatment of patients.
