This book is a collection of articles written by prominent scientists who gathered in the city of Recife, Brazil, 23-27 October 2010, celebrating the 10th International Symposium on Yersinia.
Il volume si propone di esaminare la struttura e le funzioni dei recettori dell’angiotensina e le ricadute delle conoscenze acquisite sull’argomento sul piano terapeutico.
This book Alternative Splicing and Cancer explores the crucial role alternative splicing, a post-transcriptional process, plays in human health and diseases, particularly cancer.
Microarray technology is a major experimental tool for functional genomic explorations, and will continue to be a major tool throughout this decade and beyond.
Epigenetic mechanisms (DNA modifications, histone alterations and non-coding RNAs) are crucial for transcriptional regulation and alterations of the "e;physiological epigenome"e; are increasingly associated with human diseases.
Upon wresting the control of the earth from the Titans, Zeus assigned the task of creating living creatures to two Titan brothers who had sided with him in the epic battle just concluded.
This detailed volume explores the methods used for most of the recent approaches to suicide gene therapy of cancer, which exploits promoters that are specific to cancer cells, thereby ensuring (or greatly increasing the likelihood) that the therapeutic gene is expressed only in cancer cells.
There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes.
This book provides a detailed evidence-based overview of the latest developments in how the structure of the human genome is relevant to the health professional.
This volume covers the structures, properties, and functions of G-quadruplexes in a wide range of biological disciplines, including therapeutic intervention and biomaterial application.
The study of immunology encompasses a vast and ever-growing body of information that in some way or other incorporates most areas of medical biological research.
In this book, leading international experts analyze state-of-the-art advances in gene transfer vectors for applications in inherited disorders and also examine the toxicity profiles of these methods.
This volume is divided in four sections; covering genome wide approaches, techniques for characterize of paRNA structural features are described, selecting pa-RNA, and paRNA therapeutic potential.
This book comprehensively accounts the current understanding of genetic mechanisms of obesity by analyzing obesity phenotypes and genotypes and, gene polymorphisms and mutations, and current results from animal model research and genetic studies in human models.
A Statistical Approach to Genetic Epidemiology After studying statistics and mathematics at the University of Munich and obtaining his doctoral degree from the University of Dortmund, Andreas Ziegler received the Johann-Peter-S ssmilch-Medal of the German Association for Medical Informatics, Biometry and Epidemiology for his post-doctoral work on Model Free Linkage Analysis of Quantitative Traits in 1999.
Benign & Pathological Chromosomal Imbalances systematically clarifies the disease implications of cytogenetically visible copy number variants (CG-CNV) using cytogenetic assessment of heterochromatic or euchromatic DNA variants.
This handy volume, that can also serve as an integration to the preceding work Cellular Primary Immunodeficiencies by the same editor, presents detailed state of the art knowledge on Severe Combined Immunodeficiency (SCID) with extensive coverage of both basic science discoveries and the latest clinical advances in the field.
This book covers all the recent research highlights of arrhythmogenic right ventr- ular cardiomyopathy/dysplasia (ARVC/D), a recently discovered heart muscle d- ease which is a major threat to the life of affected young people.
