Ornithine Transcarbamylase: Basic Science and Clinical Considerations, written by a leading expert on OTC, for the first time assembles and analyzes more than 40 years of basic science and clinical research.
Given this pervasiveness and importance of miRNA-mediated gene regulation, it should come as little surprise that miRNAs themselves are also highly regulated.
Books on bioinformatics which began appearing in the mid 80s primarily served gene-hunters, and biologists who wished to construct family trees showing tidy lines of descent.
This book covers the statistical models and methods that are used to understand human genetics, following the historical and recent developments of human genetics.
This volume will explore the epidemiology and the basic mechanisms of each of these prenatal phenomena, in an attempt to explain the role of the prenatal environment in promoting postnatal weight gain.
BetaSys uses the example of regulated exocytosis in pancreatic -cells, and its relevance to diabetes, to illustrate the major concepts of systems biology, its methods and applications.
The second edition of Inherited Cancer Syndromes incorporates new genetic markers data with the clinical utility and practicality of the first edition.
In his 1894 book, Materials for the Study of Variation, William Bateson coined the term Homoeosis with the following prose: The case of the modification of the antenna of an insect into a foot, of the eye of a Crustacean into an antenna, of a petal into a stamen, and the like, are examples of the same kind.
Since this book is geared to be used by varied groups of readers such as advanced students and instructors in the fields of biology and medicine, scientists and more importantly clinicians, it is considered important to provide brief accounts of the basics of DNA damage, repair, mutagenesis and cancer.
In Fragile X-Associated Tremor Ataxia Syndrome (FXTAS), the editors present information on all aspects of FXTAS, including clinical features and current supportive management, radiological, psychological, and pathological findings, genotype-phenotype relationships, animal models and basic molecular mechanisms.
System Biology encompasses the knowledge from diverse fields such as Molecular Biology, Immunology, Genetics, Computational Biology, Mathematical Biology, etc.
Gene Expression and its Discontents examines a class of probability models describing how epigenetic context affects gene expression and organismal development, using the asymptotic limit theorems of information theory in a highly formal manner.
Developmental genetic studies of the spine and linkage and family-based association studies have led to recent advances in understanding the genetic etiology of idiopathic, neuromuscular, and congenital forms of scoliosis.
This volume will explore the latest findings in research into the genetics of breast and reproductive cancers, covering the epidemiological aspects of these cancers, their etiology, the effect of environment on genes and cancer etiology, and how research in this area can lead to development of preventative measures and treatments.
Knowledge about cancer genetics is rapidly expanding, and has implications for all aspects of cancer research and treatment, including molecular causation, diagnosis, prevention, screening, and treatment.
Karch's Drug Abuse Handbook, Third Edition remains the quintessential compendium addressing the pharmacological, medical, and legal aspects of drugs and informing the forensic community of the latest scientific advances and emergent practices.
Addressing the increased use of protein and peptide candidates as treatments for previously untreatable diseases, this comprehensive and progressive source provides the reader with a roadmap to an increased understanding of issues critical for successfully developing a protein or peptide therapeutic candidate.
Maintaining the first edition's unique parallel to the strategy used by pathologists and pulmonologists to arrive at a patient's diagnosis in daily practice, Diagnostic Pulmonary Pathology starts with the patient and their biopsy findings, directing the pathologist or clinician to the proper diagnosis.
Now in its second edition, this bestselling title has been extensively revised and expanded to include new topics on:obesity and breast cancerinduction of anti-hormone and anti-growth factor resistance in breast cancerclinical implications of testosterone and breast cancerinsulin-like growth factorsdiscussions on the biological, genetic, and molecu
Hereditary Gynecologic Cancer: Risk, Prevention and Management fills the need that exists for a book addressing highly relevant clinical issues associated with the new field of hereditary gynecologic cancers.
Beginning with a definition and explanation of scheduling of controlled substances, Pathology, Toxicogenetics, and Criminalistics of Drug Abuse covers investigative methods for all illegal drugs and several legitimate pharmaceuticals that are used illicitly, including steroids.
Written by a panel of experts, Methods in Alcohol-Related Neuroscience Research not only provides information of a technical nature but also gives an overview of the many areas in investigating the effects of alcohol on the brain.
Translating bench-based research into effective bedside practice, this source provides a clear understanding of the neurobiology and neurogenetics of psychiatric disorders, the genes responsible for specific psychiatric disorders, and the implications of genetic roots and underlying biology on the development of new diagnostic approaches and treatment therapies.
An authoritative collection of recent breakthroughs in Parkinson's Disease (PD) research, Parkinson's Disease: Genetics and Pathogenesis spans key findings on the mechanisms of neurodegeneration and the role of specific genes that may lead to improved therapies for PD.
Intended for medical oncologists, surgeons, obstetricians, gynecologists, geneticists, genetic counselors, and primary care physicians, this text presents the epidemiological, biological, and clinical issues associated with hereditary breast cancer.
